Protein Alignment Iswi and zranb3

DIOPT Version :10

• Sequence 1: NP_523719.1
• Gene: Iswi / 36390
• FlyBaseID: FBgn0011604
• Length: 1027
• Species: Drosophila melanogaster
• Sequence 2: XP_017208927.2
• Gene: zranb3 / 553237
• ZFINID: ZDB-GENE-060712-1
• Length: 1079
• Species: Danio rerio
• Alignment Length: 1019
• Identity: 223/1019 - (21%)
• Similarity: 359/1019 - (35%)
• Gaps: 295/1019 - (28%)

  Fly   127 EMRDYQIRGLNWMISLYENGINGILADEMGLGKTLQTISLLGYLKHFKNQAGPHIVIVPKSTLQN 191
            ::..:|..|:.:.:|  .|| ..::|||||||||:|.|| :.|:  || |..|.:::||.|....
Zfish    35 KLMPFQREGVCFALS--RNG-RCMIADEMGLGKTIQAIS-VAYI--FK-QEWPLLIVVPSSLKYP 92

  Fly   192 WVNEFKKWCPSL--RAVCLIGDQ-DTRNTFIRDVLMPGEWDVCVTSYEMCIREKSVFKKFNWRYL 253
            |:.|.:||.|.|  |.:.|:..: ||.:.....|.:.| :.:..|.....:   ....|..:..:
Zfish    93 WIEELEKWIPELDPRDINLVESKTDTMSISTSKVTILG-YGLLTTDARALL---EALNKQQFAVV 153

  Fly   254 VIDEAHRIKNEKSKLSEILRE-FKTANR-LLITGTPLQNNLHELWALLNFLLPDVFNSSEDF-DE 315
            ::||:|.:|:..:..|:||.. .::|.| :|:||||......||:..::.|.|..|.:..|: ::
Zfish   154 LVDESHYLKSRNAARSKILVPIIQSAKRAILLTGTPALGRPEELFMQIDALYPRRFGTWSDYANK 218

  Fly   316 WFNTN----------TCLGDDALITRLHAVLKPFLLRRLKAEVEKRLKPKKEMKIFVGLSKMQRD 370
            :.|.:          .|.|...| ..||..|...::||||.:|..:|.||...:|...|.|
Zfish   219 YCNAHYRYFGARRQWDCRGASHL-DELHKRLSEIMIRRLKNQVLTQLPPKIRQRIPFDLPK---- 278

  Fly   371 WYTKVLLKDIDVVNGAG-------KVEKMRLQNILMQLRKCTNHPYLFDGAEPGPPYTTDTHLVY 428
                      |....|.       |:.....:|..:::.....|.|             ....|.
Zfish   279 ----------DAAKEASASFEQWEKLMSSESENQFVEVMSLITHMY-------------KQTAVA 320

  Fly   429 NSGKMAILDKLLPKLQEQGSRVLIFSQMTRMLDILEDYCHWRNYNYCRLDGQTPHEDRNRQIQEF 493
            .:|  |:.|.:...|:.:..:.|:|:....||....:........|.|:||..|..:|.:.:..|
Zfish   321 KAG--AVKDYIKMMLESEQLKFLVFAHHLSMLQACTEAVIEAKAGYIRIDGSVPSAERIQLVHRF 383

  Fly   494 NMDNSAKFLFMLSTRAGGLGINLATADVVIIYDSDWNPQMDLQAMDRAHRIGQKKQVRVFRLI-- 556
            ..|...: :.:||.:|.|.|:....|..|:..:..|||....||.||||||||...|.:..||
Zfish   384 QNDPDTR-VAVLSIQAAGQGLTFTAASHVVFAELYWNPGHIKQAEDRAHRIGQTATVHIHYLIAK 447

  Fly   557 -TESTVEEKIVERAEVKLRLDKMVIQGGRLVDNRSNQLNKDE-------MLNIIR-FGANQVFSS 612
             |..||...::.|.|...         |..::.:...|..:|       .||..: :..||:...
Zfish   448 GTFDTVMWAMLNRKETVT---------GSALNGKKEYLKAEEGDQEKWDFLNFAQAWTPNQMLKG 503

  Fly   613 KETDITD------------EDIDVILERGEAKTAEQKAALDSLGESS---------LRTFTMDTN 656
            ...|..|            .||.........|..::|...||..:.|         ..|.|.:|.
Zfish   504 DSEDDKDGVFFSHFERDKQHDIRSFFSPSVHKEKKRKRTEDSTSDGSPLPQLPAGAEPTQTPETQ 568

  Fly   657 GEAGTSSVYQFEGEDWREKQKLNALGNWIEPPKRERKANYAVDAYFREALRVSEPKAPKAPRPPK 721
            ....|:.    :|||:              .|:.:|         ||:...:|.....|:|..|
Zfish   569 SFDLTAD----QGEDF--------------SPQVKR---------FRQVSPLSRRGGKKSPLSP- 605

  Fly   722 QPIVQDFQFFPPRLFELLDQEIYYFRKTVGYKVPKNTE---------------LGSDATKVQREE 771
                    .|.||            |.:.|.:.|::.:               |..:.....|..
Zfish   606 --------LFAPR------------RLSAGLQAPRHNQKWNCSSCTFSNSGLLLRCEMCDSPRNV 650

  Fly   772 QRKID------------------------EAEPLTEEEIQEKENLLSQGFTAWTKRDFNQFIKAN 812
            |:.:.                        |.||.|..:||...            :..||....|
Zfish   651 QKALSPPSSLADPSSSSSLTTICISDSDTENEPSTSSKIQTPH------------KHPNQQASPN 703

  Fly   813 EKYGRDDIDNIAKDVEGKTPE----EVIEYNAVFWER--CTELQDIERIMGQIERGEGKIQRRLS 871
            ......||    .:.:|.||:    :....:..:.|.  |..:.|..:...      .|...|:.
Zfish   704 VAETHKDI----SEEQGSTPKTFNGDSANDDGAYEESGDCVSVYDCLKFCA------SKNTDRIY 758

  Fly   872 I--KKALDQKMSRYRAPFH------QLRLQYGNNKGKNYTEIEDRFLVCMLHKLGFDKENVYEEL 928
            |  |..|         |.|      .:|||       |:.|:...|             |..:..
Zfish   759 IHDKDGL---------PLHCNFIPLDIRLQ-------NWEELPPEF-------------NHSQNR 794

  Fly   929 RAAIRASPQFRFDW----FIKSRTALELQRRCNTLITLIERENIELEEKER-------------- 975
            |..:|    |..:|    .:|.|...:..|..::.|.|:|    ||.:.:|
Zfish   795 RQVVR----FVREWSSLTAMKQRMVRKSGRVFHSPILLLE----ELTQSQRRHSSTSRYLSKHDV 851

  Fly   976 -------AEKKKKA----PKGSVSAGSGSASSNTPAPAPQPKAS 1008
                   |:|:..|    .|.||:....|.|.....|..:|::|
Zfish   852 AQTSIAVAQKEGGALRIINKDSVAFKRTSTSKPADPPNREPESS 895

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Iswi	NP_523719.1	PLN03142	46..967	CDD:215601	209/951 (22%)
zranb3	XP_017208927.2	None