Protein Alignment Iswi and Marcal1

DIOPT Version :10

• Sequence 1: NP_523719.1
• Gene: Iswi / 36390
• FlyBaseID: FBgn0011604
• Length: 1027
• Species: Drosophila melanogaster
• Sequence 2: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Alignment Length: 895
• Identity: 189/895 - (21%)
• Similarity: 298/895 - (33%)
• Gaps: 322/895 - (35%)

  Fly     3 KTDTAAVEATEE----NSNETTSDAAT------SSSGE--------------KEAEFDNKIEADR 43
            |:.|:|..||:.    .||.....|.:      |.:||              |.:.|.|.::|
  Fly    37 KSTTSATGATQHANNGKSNPNQPQAKSPLNFYRSPTGEQKKINRSGPTPGDNKSSSFLNALKA-- 99

  Fly    44 SRRFDFLLKQTEIFTHFMTNSAKSP-TKPKG-----RPKKIKDKDKEKDVA-------------- 88
                   :|||.  ...::..|..| .:|.|     :|......||||.||
  Fly   100 -------IKQTS--NRELSRGAAHPYQRPNGGNERNKPTLSLSSDKEKPVAVLLGNSITCNLYLI 155

  Fly    89 -DHRHRKTEQEEDEELLA--EDSATK------EIFRFDASPAYIKSGEMRDYQ------------ 132
             .||.........|:|:.  ::..||      .|:.||.|          |||
  Fly   156 STHRFAAQTSGYHEQLVTVFKNMPTKCYDGQTRIWSFDLS----------DYQSLKTHAADLKPY 210

  Fly   133 --IRGL----------------------------NWMISLYENGI------NG--ILADEMGLGK 159
              :.|:                            :.::...::|:      .|  ::.|||||||
  Fly   211 VHMNGIPKKVLDLCGQPPVVPERSVLASIEPKLADQLMPFQQDGVCFAIAQKGRIMICDEMGLGK 275

  Fly   160 TLQTISLLGYLKHFKNQAGPHIVIVPKSTLQNWVNEFKKWCPS--LRAVCLIGDQDTRNTFIRDV 222
            |.|.:::..|.|    ...|.:|....||..:|........|.  :..|.::.:..
  Fly   276 TYQALAVADYFK----DDWPLLVCTTASTRDSWAKHIMDLLPKVPIHYVQVLNNNQ--------- 327

  Fly   223 LMPGEWDVCVTSYEMCIREKSVFKKFNWRYLVIDEAHRIKNEKSKLSEILREFKTANRL------ 281
            |..||..|.:|||.|..|.:....:..:.:::.||:|.:||.|:|.:      .||.||
  Fly   328 LYVGEAKVLITSYNMMERHEDKLMQRKFGFIIFDESHTLKNSKAKCT------TTAKRLTDQAKR 386

  Fly   282 --LITGTPLQNNLHELWALLNFLLPDVFNSSEDFDEWFNTNTCLGDDAL----------ITRLHA 334
              |::|||..:...||:..|..:.....|..|     |.|..|.|..:.          :..|..
  Fly   387 VVLLSGTPALSRPLELFTQLQMIDGKFMNFME-----FTTRYCDGKQSTFGWDANGQSNLEELKV 446

  Fly   335 VLK-PFLLRRLKAEVEKRLKPKKEMKIFVGLSKMQRDWYTKVLLKDIDVVNGAGKVEKMR-LQNI 397
            :|. .::|||.|.||..:|..|....:.:..:.:   |......:.:|..|...|..|.| .:.|
  Fly   447 ILHLKYMLRRTKVEVLPQLAEKNRETVVLDPALV---WTNAETKETLDAFNKELKTAKGRATEEI 508

  Fly   398 LMQLRKCTNHPYLFDGAEPGPPYTTDTHLVYNSGKMAILDKLLPKLQEQGSRVLIFSQMTRMLDI 462
            |::.                  |.....:     |...:...|..|.::..:.:||:....|:|.
  Fly   509 LLRF------------------YARTAEV-----KTRAVCAYLKTLVKEQKKFIIFAHHRVMMDA 550

  Fly   463 LEDYCHWRNYNYCRLDGQTPHEDRNRQIQEFNMDNSAKFLFMLSTRAGGLGINLATADVVIIYDS 527
            :.|:......:|.|:||||..:.|:..:..|...:|.| :.:||.:|...||.|..|::::..:.
  Fly   551 ISDFLSGLKVHYIRIDGQTRSDHRSDSVDTFQKKSSCK-VALLSLKACNSGITLTAAEIIVFAEL 614

  Fly   528 DWNPQMDLQAMDRAHRIGQKKQVRVFRLITESTVEEKIVERAEVKLRLDKMVIQGGRLVDNRSNQ 592
            ||||....||..|||||||.|.|....||..:|.::.|                        .|.
  Fly   615 DWNPSTLAQAESRAHRIGQTKPVICRYLIAHNTADDII------------------------WNM 655

  Fly   593 L-NKDEMLNIIRFGANQVFSSKETDITDEDIDVILERGEAKTAEQKAALDSLGESSLRTFTMDTN 656
            | ||.|:|:.:...|..:                          |||                |:
  Fly   656 LKNKQEVLSKVGIFAENL--------------------------QKA----------------TH 678

  Fly   657 GEAGTSSVYQFEGEDWREKQKLNALGNWIEPPKRERKANYAVDAYFREALRVSEPKAPKAPRPPK 721
            ..|.|||                                :.::.||       .|....:..|.:
  Fly   679 TAAPTSS--------------------------------HKIEEYF-------SPSTSTSLEPER 704

  Fly   722 QPIVQDFQFFPPRLFELLDQEIYYFRKTVGYKVPKNTELGSDATKVQREE 771
            ..|.|                  || .|:..|.|......::.|||.:.|
  Fly   705 NSIKQ------------------YF-STIPAKEPPEQNNNTEMTKVNKAE 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Iswi	NP_523719.1	PLN03142	46..967	CDD:215601	174/828 (21%)
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	11/65 (17%)
		HepA	<233..666	CDD:440319	122/507 (24%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	56/232 (24%)