Protein Alignment Iswi and Rad54l

DIOPT Version :10

• Sequence 1: NP_523719.1
• Gene: Iswi / 36390
• FlyBaseID: FBgn0011604
• Length: 1027
• Species: Drosophila melanogaster
• Sequence 2: NP_001128432.1
• Gene: Rad54l / 298429
• RGDID: 1310600
• Length: 748
• Species: Rattus norvegicus
• Alignment Length: 557
• Identity: 171/557 - (30%)
• Similarity: 274/557 - (49%)
• Gaps: 90/557 - (16%)

  Fly   123 IKSGEMRDYQIRGLNWMISLYEN----GING-ILADEMGLGKTLQTISLLGYLKHFKNQAGPHI- 181
            |.|..:|.:|..|:.::.....:    |.:| |:|||||||||||.|:|:..|.....:..|.|
  Rat   148 ILSKVLRPHQREGVKFLWECVTSRRIPGSHGCIMADEMGLGKTLQCITLMWTLLRQSPECKPEIE 212

  Fly   182 ---VIVPKSTLQNWVNEFKKWCPS-LRAVCLIG---DQDTRNT--FI--RDVLMPGEWDVCVTSY 235
               |:.|.|.::||.||.:||... ::.:.:.|   |:..|..  |:  |...:|.  .:.:.||
  Rat   213 KAVVVSPSSLVKNWYNEVEKWLGGRIQPLAIDGGSKDEIDRKLEGFMNQRGARVPS--PILIISY 275

  Fly   236 EMCIREKSVFKKFNWRYLVIDEAHRIKNEKSKLSEILREFKTANRLLITGTPLQNNLHELWALLN 300
            |.......|.||.|...::.||.||:||.:::..:.|....|:.|:||:|||:||:|.|.::|::
  Rat   276 ETFRLHVEVLKKGNVGLVICDEGHRLKNSENQTYQALDSLNTSRRVLISGTPIQNDLLEYFSLVH 340

  Fly   301 FLLPDVFNSSEDFDEWF-------------NTNTCLGDDALITRLHAVLKPFLLRRLKAEVEKRL 352
            |:...:..::.:|.:.|             ..:..||::.| ..|.:::...|:||....:.|.|
  Rat   341 FVNSGILGTAHEFKKHFELPILKSRDAAASEADRQLGEERL-RELISIVNRCLIRRTSDILSKYL 404

  Fly   353 KPKKEMKIFVGLSKMQRDWYTKVL--LKDIDVVNGAGKVEKMRLQNILMQLRKCTNHPYLF---- 411
            ..|.|..:...|:.:|.:.|.:.|  .|..:.:: .||:....|.:| ..|:|..|||.|.
  Rat   405 PVKIEQVVCCRLTPLQTELYKRFLRQAKPEEELH-EGKMSVSSLSSI-TSLKKLCNHPALIYDKC 467

  Fly   412 ----DGAE-------PGPPYTTDTHLVYN--------SGKMAILDKLLPKLQEQGS-RVLIFSQM 456
                ||.|       ||          ||        ||||.:||.:|...:.:.| :|::.|..
  Rat   468 VAEEDGFEGTLGIFPPG----------YNSKAVEPQLSGKMLVLDYILAMTRSRSSDKVVLVSNY 522

  Fly   457 TRMLDILEDYCHWRNYNYCRLDGQTPHEDRNRQIQEFNMDNSAKFLFMLSTRAGGLGINLATADV 521
            |:.||:.|..|..|.|.|.||||....:.|.:.::.||..:|..|:||||::|||.|:||..|:.
  Rat   523 TQTLDLFEKLCRARRYLYVRLDGTMSIKKRAKVVERFNSPSSPDFVFMLSSKAGGCGLNLIGANR 587

  Fly   522 VIIYDSDWNPQMDLQAMDRAHRIGQKKQVRVFRLITESTVEEKIVERAEVKLRLDKMVIQGGRLV 586
            ::::|.||||..|.|||.|..|.||||...::||::..|:||||.:|...|..|...|:
  Rat   588 LVMFDPDWNPANDEQAMARVWRDGQKKICYIYRLLSAGTIEEKIFQRQSHKKALSSCVV------ 646

  Fly   587 DNRSNQLNKDEMLNIIRFGA----NQVFSSKETDITD 619
                     ||..::.|..:    .::|:..|..::|
  Rat   647 ---------DEEQDVERHFSLGELKELFTLDEASLSD 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Iswi	NP_523719.1	PLN03142	46..967	CDD:215601	171/557 (31%)
Rad54l	NP_001128432.1	HepA	<90..647	CDD:440319	165/528 (31%)
		DEXHc_RAD54A	153..395	CDD:350825	71/244 (29%)