Protein Alignment Iswi and csb-1

DIOPT Version :10

• Sequence 1: NP_523719.1
• Gene: Iswi / 36390
• FlyBaseID: FBgn0011604
• Length: 1027
• Species: Drosophila melanogaster
• Sequence 2: NP_510607.2
• Gene: csb-1 / 181674
• WormBaseID: WBGene00000803
• Length: 957
• Species: Caenorhabditis elegans
• Alignment Length: 995
• Identity: 231/995 - (23%)
• Similarity: 400/995 - (40%)
• Gaps: 228/995 - (22%)

  Fly     5 DTAAVEATEENSNETTSDAATSSSGEKEAEFDNKIEADRSRRFDFLLKQTEIFTHFMTNSAKSPT 69
            |...:...|:.:.....:||...|....::||.|.|.:.... ||.....::    :.....|.:
 Worm    21 DDDDIVVIEDQNTPKYREAALRRSNSSSSDFDEKWEPELDEE-DFCENDADV----LAEPISSKS 80

  Fly    70 KPKGR--------PKKIKDKDKEKDVADHRHRK---------------TEQEEDEEL----LAED 107
            :.|.|        |.:..|.|:|.:|.:...:|               .|.:::|:.    |.:|
 Worm    81 RKKSRRSDSSEFVPSEESDDDEEYEVLEKSRKKGRKSGSSSRSSSDDFIESDDNEDYKSAGLLDD 145

  Fly   108 S---------------ATKEIF--RFDASPAYIKS-----------GEMRDYQIRGLNWMISLYE 144
            :               ||.|:.  |...|..|.||           .::..:|..|:.|:....:
 Worm   146 NDSKNFKARIDKLKPEATSELVDTRMVTSEEYGKSSKPWKVNAGVWNKLHKFQQEGVEWLQKKTD 210

  Fly   145 NGINGILADEMGLGKTLQTISLLGYLK-----HFKNQA-GPHIVIVPKSTLQNWVNEFKKWCPSL 203
            :...||||||||||||:|::..|..::     |:|... ...:::...|.:..|:.|..:|.|..
 Worm   211 HRSGGILADEMGLGKTIQSVVFLRSIQETARTHYKTTGLDTALIVCHVSIIAQWIKELNQWFPKA 275

  Fly   204 RAV-----CLIGDQDT------RNTFIRDVLMPGEWDVCVTSYEMCIREKSVFKKFNWRYLVIDE 257
            |..     |..|.|:.      |....|....| :..:.:|:|.:..:.|....|..|:.:::||
 Worm   276 RVFLLHSHCSTGRQEDYVGSIFRKLQRRRKEYP-DGAIILTTYSLFTKLKKPIVKHLWQVVILDE 339

  Fly   258 AHRIKNEKSKLSEILREFKTANRLLITGTPLQNNLHELWALLNFLLPDVFNSSEDFDEWF----- 317
            .|.|:||.:|.|..:|:..|..|.::||||.||.|.|.|.|::|:.|...:.|..|...|
 Worm   340 GHYIRNENTKCSIAMRKLMTTQRFILTGTPFQNRLSEFWKLVDFVHPGRLSDSATFHRNFTHIIN 404

  Fly   318 ---NTNTCLGDDA-----LITRLHAVLKPFLLRRLKAEVEK--RLKPKKEMKIFVGLSKMQRDWY 372
               |.| |..:.|     .:..||..:||.:||||:.:.::  :|..|:|:.:...|||.||..|
 Worm   405 AGANLN-CSPEAAAKAYECLVALHIAVKPLILRRLQEDHKEVLQLPEKQEIVLSCELSKRQRRLY 468

  Fly   373 TKVLLKDIDVVNG--AGKVEKMRLQNI--LMQLRKCTNHPYLFDGAEPGPPYTTDTHLVYNSGKM 433
                   ::..|.  ..::.:.||:..  :..|....|||.::....|..|....   :.:|||:
 Worm   469 -------MEYGNSHQVNEIIERRLKAFVGINHLTNICNHPGIYRSLSPASPKFGS---IKDSGKV 523

  Fly   434 AILDKLLPK-LQEQGSRVLIFSQMTRMLDILEDYCHWRNYNYCRLDGQTPHEDRNRQIQEFNMDN 497
            .:..||... .:...:||::|:|...::.::|.:...:......|.|......|.:.|::|..|.
 Worm   524 EMTFKLFDDWFKSPTNRVILFTQRRTVITMMEYFLAEKGIKCVSLTGADSAAARPKIIKKFEDDV 588

  Fly   498 SAKFLFMLSTRAGGLGINLATADVVIIYDSDWNPQMDLQAMDRAHRIGQKKQVRVFRLITESTVE 562
            |.| :|:::|||||||:||..|:.|||:|.|||||.|.||.:|.:|:||...|.::||::..|:|
 Worm   589 SIK-VFLMTTRAGGLGLNLTCANKVIIFDPDWNPQADNQAKNRIYRMGQTNDVAIYRLVSNGTIE 652

  Fly   563 E--------------KIVERAEVK-----------LRLDKMVIQG--------GRLVDNRSNQLN 594
            :              :::..||:.           .||....::|        |.:....|.:..
 Worm   653 DLKFFKQVQKENLAARLLHNAEIDQFVPNNTLADLFRLKPKGLEGSEIGVYLDGEIAREGSKKQK 717

  Fly   595 KDEMLNIIRFGANQVFSSKETDITD--------EDIDVILERGEAKTAEQKAALDSLGESSLRTF 651
            :|:   :.:..|.:...:|.....|        :|..::..|..:.:.:..::::.:.:..:|..
 Worm   718 RDK---VEKKAAKKRMKNKLAGFEDKKLLLSLFDDDKLVAMREHSISLQNSSSMNRIEKMKMRKS 779

  Fly   652 TMDTNGEAGTSSVYQFEG---EDWRE---KQKLNALGNWIEPPKRERKANYAV-----DAY---- 701
            ..|..|     |:...||   ..|::   ||....|       |:....:|.|     |:|
 Worm   780 IDDAVG-----SLLHTEGRLAHTWKQVFHKQLRKTL-------KKSINGDYFVEEEQLDSYWNTV 832

  Fly   702 ---FREALRVSEPKAPKAPRPPKQPIVQDFQFFPPRLFELLDQEIYYFRKTVGYKVPKNTELGSD 763
               ||                     ..|.|....||.:|....:.:|.     .||     |:.
 Worm   833 HSGFR---------------------ANDDQRELDRLVKLATDMLQFFN-----GVP-----GAK 866

  Fly   764 ATKVQREEQRKIDEAEPLTEEEIQEKENLLSQ---GFTAWTKRDFNQF------IKANEKYGRDD 819
            ...:.|...:..|..:|.....|||..:.|::   ....|..||..:.      :|...|...||
 Worm   867 EDSIHRIFVKDSDRKDPTQMFFIQEIISTLAKYDDASDTWILRDKYRSADVLSPVKKKNKRRSDD 931

  Fly   820 IDNIAKDVEGKTPEEVIEYN 839
            .|    :|:.|...:..|::
 Worm   932 ND----EVDAKRARKSREWS 947

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Iswi	NP_523719.1	PLN03142	46..967	CDD:215601	222/954 (23%)
csb-1	NP_510607.2	HepA	<193..670	CDD:440319	142/489 (29%)