Protein Alignment Iswi and Etl1

DIOPT Version :10

• Sequence 1: NP_523719.1
• Gene: Iswi / 36390
• FlyBaseID: FBgn0011604
• Length: 1027
• Species: Drosophila melanogaster
• Sequence 2: XP_061519079.1
• Gene: Etl1 / 1279402
• VectorBaseID: AGAMI1_014601
• Length: 868
• Species: Anopheles gambiae
• Alignment Length: 612
• Identity: 226/612 - (36%)
• Similarity: 320/612 - (52%)
• Gaps: 99/612 - (16%)

  Fly    37 NKIEADRSRRFDFLLKQTEIFTHFMTNSAKSPTKPKGRPKKIKDKDKEKDVADHRHRKTEQEEDE 101
            :|:::.||.:.| :|..|:.:.....|.|...:|.|...||:                      |
Mosquito   243 DKLKSHRSLQTD-ILNYTQEYLTRRKNIAAMMSKCKKITKKL----------------------E 284

  Fly   102 ELLAEDSATKEIFRFDASPAYIKSG-EMRDYQIRGLNWMISLYENGINGILADEMGLGKTLQTIS 165
            |.:|..|.|     ....|..|..| ::.:||:.||||:..:|.:.:|.|||||||||||:|.|:
Mosquito   285 EAIASGSGT-----LVEQPGNIADGFKLAEYQLVGLNWLTIMYRHKMNAILADEMGLGKTIQIIA 344

  Fly   166 LLGYLKHFKNQAGPHIVIVPKSTLQNWVNEFKKWCPSLRAVCLIGDQDTRNTFIRDVLMPG--EW 228
            .|.:||...:|..|::|:||.||:.||..|..||||.|..:...|.|..|.....|....|  |.
Mosquito   345 FLAWLKENNHQERPNLVVVPSSTMDNWEQELVKWCPELVILKYYGSQAERRMIRVDWAKNGINEV 409

  Fly   229 DVCVTSYEM---CIREKSVFKKFNWRYLVIDEAHRIKNEKSKLSEILREFKTANRLLITGTPLQN 290
            ||.:|:|.|   ...||.:::...:.|:|.||||.:||..|:..:.|.......|:|:|||||||
Mosquito   410 DVVLTTYHMMGASGEEKKMWRVTQFDYVVFDEAHMLKNVHSQRYQNLIRINAKYRILLTGTPLQN 474

  Fly   291 NLHELWALLNFLLPDVFNSS-EDFDEWF----NTNTCLGDDAL-------ITRLHAVLKPFLLRR 343
            ||.||.:||.|::|.:..|. ||....|    .||...|::.|       |.|...::|||:|||
Mosquito   475 NLLELMSLLCFVMPKLIGSKVEDIKTLFQGKVKTNKGEGEEELSSFEKNQIDRAKLIMKPFVLRR 539

  Fly   344 LKAEVEKRLKPKKEMKIFVGLSKMQRDWYTKVLLKDIDVVNGAGKVE---KMRLQNILMQLRKCT 405
            ||.:|...|.||||:.:...:...|::.|.:::   .:..|..|||:   ::...:|:|.|||..
Mosquito   540 LKKDVLAFLPPKKEVVLKTSMIDSQQEKYNEIV---NEYQNATGKVKDYTEISGMSIMMDLRKLA 601

  Fly   406 NHPYL--------------------------------FDGA--------EPGPPYTT------DT 424
            |||.|                                :|.|        |....|||      ..
Mosquito   602 NHPLLLRYYYSDDDVRNIARKLATDPDYKGTKEDDIFYDIAYLSDFKLYEMRDKYTTLYDLQLPE 666

  Fly   425 HLVYNSGKMAILDKLLPKLQEQGSRVLIFSQMTRMLDILEDYCHWRNYNYCRLDGQTPHEDRNRQ 489
            .|:.:|||...||:||||::|:|.|||||||.|.||||:|.|...|.:.:.||||.|...:|...
Mosquito   667 KLITSSGKFRQLDELLPKMKEEGHRVLIFSQFTMMLDIMERYLKIRKHGFLRLDGSTAVTERQEL 731

  Fly   490 IQEFNMDNSAKFLFMLSTRAGGLGINLATADVVIIYDSDWNPQMDLQAMDRAHRIGQKKQVRVFR 554
            |.::..|... |:|:|||:||||||||..||.|||:|.|:||..|.||.|||||:||||.|.:::
Mosquito   732 IDQYTQDPDL-FIFLLSTKAGGLGINLTAADTVIIHDIDFNPYNDKQAEDRAHRMGQKKPVTIYK 795

  Fly   555 LITESTVEEKIVERAEVKLRLDKMVIQ 581
            ||:|.|:||.::..|:.||:|:|.|.:
Mosquito   796 LISEGTIEEGMLMIAQQKLQLEKDVTE 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Iswi	NP_523719.1	PLN03142	46..967	CDD:215601	223/603 (37%)
Etl1	XP_061519079.1	None