Protein Alignment Iswi and chd6

DIOPT Version :10

• Sequence 1: NP_523719.1
• Gene: Iswi / 36390
• FlyBaseID: FBgn0011604
• Length: 1027
• Species: Drosophila melanogaster
• Sequence 2: XP_004918574.2
• Gene: chd6 / 100498254
• XenbaseID: XB-GENE-5964535
• Length: 2667
• Species: Xenopus tropicalis
• Alignment Length: 1068
• Identity: 318/1068 - (29%)
• Similarity: 480/1068 - (44%)
• Gaps: 241/1068 - (22%)

  Fly    24 ATSSSGEKEAEFDNKIEADRSRRFDFLLKQTEIFTHFMTNSAKSPTKPKGRPKKIKDKDKEKDVA 88
            ||....||:.....||:..|:::    .:...|||        .|.:....|..: :.|:..:||
 Frog   327 ATLEELEKDPRIQQKIKRFRNKQ----AQMKHIFT--------EPDEDMFNPDYV-EVDRVLEVA 378

  Fly    89 DHRHRKTEQ----------------EEDEELLAEDSATKEIFRFDA------------------- 118
            ..:...|.:                ||....|.||....::..|:|
 Frog   379 HTKDSDTGEVREVTHFLVKWCSLPYEESTWELEEDVDPVKVKEFEALQKVPDLTPMERPASETWQ 443

  Fly   119 ----SPAYIKSGEMRDYQIRGLNWMISLYENGINGILADEMGLGKTLQTISLLGYLKHFKNQAGP 179
                |..|..:.::|:||:.|:||::..:.|..|.|||||||||||:|:|:.|..: .|....||
 Frog   444 KLVSSRTYKNNNQLREYQLEGMNWLLFNWYNRKNCILADEMGLGKTIQSITFLSEI-FFMGIRGP 507

  Fly   180 HIVIVPKSTLQNWVNEFKKWCPSLRAVCLIGDQDTR------NTFIRD---VLMPG--EWDVCVT 233
            .::|.|.||:.||..||:.| ..:..:...|.|.:|      ..:.||   ..:||  ::.:.:|
 Frog   508 FLIIAPLSTITNWEREFRTW-TEMNTIVYHGSQISRQMIHQYEMYYRDEQGTPIPGIYKFQIVIT 571

  Fly   234 SYEMCIREKSVFKKFNWRYLVIDEAHRIKNEKSKLSEILREFKTANRLLITGTPLQNNLHELWAL 298
            ::||.:.:....||..|..::||||||:||...||.|.|:.....:::|:|||||||::.||::|
 Frog   572 TFEMILADCPELKKIRWSCVIIDEAHRLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELYSL 636

  Fly   299 LNFLLPDVFNSSEDFDEWFNTNTCLGDDALITRLHAVLKPFLLRRLKAEVEKRLKPKKEMKIFVG 363
            ||||.|..|.|...|.|.|..   |..:..:.:|.::|||.:|||||.:|||.|.||:|..|.|.
 Frog   637 LNFLEPVQFPSESTFLEEFGD---LKTEEQVKKLQSILKPMMLRRLKDDVEKNLAPKQETIIEVE 698

  Fly   364 LSKMQRDWYTKVLLKDID-VVNGAGKVEKMRLQNILMQLRKCTNHPYLFDGAEP---------GP 418
            |:.:|:.:|..:|.|:.. :..||.:.....|.|.:|:||||.|||||.:|||.         ..
 Frog   699 LTNIQKKYYRAILEKNFTFLTKGANQHNMPNLINTMMELRKCCNHPYLINGAEEKILEDFRKRHS 763

  Fly   419 PYTTDTHL---VYNSGKMAILDKLLPKLQEQGSRVLIFSQMTRMLDILEDYCHWRNYNYCRLDGQ 480
            |...|..|   :..:||:.::|||||||...|.:|||||||.|.|||||||...|.|.|.|:||:
 Frog   764 PDALDFQLQAMIQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDILEDYLIQRRYIYERIDGR 828

  Fly   481 TPHEDRNRQIQEFNMDNSAKFLFMLSTRAGGLGINLATADVVIIYDSDWNPQMDLQAMDRAHRIG 545
            .....|...|..|...:|.:|:|:|.||||||||||..||..||:|||||||.||||..|.||||
 Frog   829 VRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIG 893

  Fly   546 QKKQVRVFRLITESTVEEKIVERAEVKLRLDKMVIQGGRLVDNRSN-----QLNKDEMLNIIRFG 605
            |.|.|:|:||||.::.|.::.::|.:||.|||.|:|.   ::.:.|     .|:|.|:.:::|.|
 Frog   894 QSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQD---INRKGNTNGVQPLSKIEVEDLLRKG 955

  Fly   606 ANQVFSSKETD---ITDEDIDVILERGEAKTAEQKAALDSLGESSLRTFTMDTNGEAGTSSVYQF 667
            |......:|.:   ..:||||.||:|                  ..:|.|:.:.|:..|.:...|
 Frog   956 AYGALMDEEDEGSKFCEEDIDQILQR------------------RTQTITIQSEGKGSTFAKASF 1002

  Fly   668 EGEDWREKQKLNALGNWIEPPKRERKANYAVDA-YFREALRVSEPKAPKAPRPPKQPIVQDFQFF 731
            .....|....|:....|   .|..:.|....|| ..:|:|.:..|:..|..:....
 Frog  1003 VSSGNRTDISLDDPNFW---QKWAKIAELDTDARNEKESLVLDRPRVRKQTKHYNS--------- 1055

  Fly   732 PPRLFELLDQEIYYFRKTVGYKVPKNTELGSDATKVQREEQRKIDEAEP-LTEEEIQEKENLLSQ 795
                ||  |.|:..|           :||.||..:.....:|..|:... |..|..:.::|||..
 Frog  1056 ----FE--DDELMEF-----------SELESDTEERPTRSRRLNDKTRRYLRAECFRVEKNLLIF 1103

  Fly   796 GFTAW-------------TKRDFNQFIKANEKYGRDDIDNIAKDVEGKTPEEVIEYNAVFWERCT 847
            |:..|             .::|.....:|...|       ..|..:|   :|.|:  :..|:..|
 Frog  1104 GWGRWKDILNLGRFKWHLNEKDMEMICRALLVY-------CVKHYKG---DEKIK--SFIWDLIT 1156

  Fly   848 --------ELQDIERIMGQIERGE--GKIQRRL-----------------------SIKKALDQK 879
                    .||:...:...:.||.  .|::.::                       |.||.|.|.
 Frog  1157 PTKDGHNQALQNHSGLSAPVPRGRKGKKLKNQMLLPEIKNADWLASCNPEIVLHDDSYKKHLKQH 1221

  Fly   880 MSRYRAPFHQLRLQY----------------GNNKGK--------NYTEI--------EDRFLVC 912
            .::.   ..::|:.|                |.|...        :|.||        .|:.|:.
 Frog  1222 CNKV---LLRVRMLYYLKAEVLGEAASRALEGENARDLEVLLPDIDYVEIPVDWWDTEADKSLLL 1283

  Fly   913 MLHKLGFDKENVYEELRAAIRASPQFRF 940
            .::|.|:::       ..|:||.|...|
 Frog  1284 GVYKHGYER-------YFAMRADPALCF 1304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Iswi	NP_523719.1	PLN03142	46..967	CDD:215601	311/1046 (30%)
chd6	XP_004918574.2	CD1_tandem_CHD5-9_like	281..347	CDD:349315	6/19 (32%)
		CD2_tandem_CHD5-9_like	366..426	CDD:349310	12/60 (20%)
		PLN03142	456..>981	CDD:215601	223/532 (42%)
		DEXHc_CHD6	457..678	CDD:350816	86/225 (38%)