DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17760 and gnav1

DIOPT Version :9

Sequence 1:	NP_001036539.1	Gene:	CG17760 / 36385	FlyBaseID:	FBgn0033756	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_001159486.1	Gene:	gnav1 / 571305	ZFINID:	ZDB-GENE-081031-92	Length:	362	Species:	Danio rerio

Alignment Length:	365	Identity:	143/365 - (39%)
Similarity:	212/365 - (58%)	Gaps:	15/365 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDCCLSDQACEER----RI-SREIDKFLKAEKKKARRELKLLVLGTGESGKTTFIKQMRIIHGKG 60
            |..||..:...|.    :| |.:||:.|....|:....:|:|:||..||||:|.:|||:|||..|
Zfish     1 MGLCLGSEVTTEEDKKAKIHSSQIDRDLYEYAKRELNVVKILLLGAAESGKSTLVKQMKIIHSHG 65

  Fly    61 FLDKERKQFTKNVFQNIFMAIQSMISAMDTLRIPYGQQEHSKLADLVKS----IDYKTVTRLEAP 121
            |..:|...|...|..|:..:::.::..|..|||.....::...|..|.|    .|   ..::..|
Zfish    66 FTKQELTSFKPAVLDNLLTSMKFVLHGMGVLRINLANPKNKVHAHSVLSCGRCFD---EDQMLFP 127

  Fly   122 YL-NAIKTLWKDAGIKECYNRRREYQLTDSTEYFLNDIARIERSDYQATDQDILHVRAPTTNIVE 185
            :: :|:..||.|.|::....|..||:|.||..||..::.||...||..|:.|:|.||..||.::|
Zfish   128 FIAHALCCLWADPGVRSSAARGYEYELNDSALYFFENMGRIIADDYMPTETDVLRVRLRTTGVIE 192

  Fly   186 YPFNLDGFLIRLVDVAGQRTERRKWIHCFSNVTSIMFLVAMSEFDLSLAESENDNRMKESKALFH 250
            ..|.:...:.|:.||.||||||||||.||..|.|::|:|::|.:|::|.|..:.||::||..||.
Zfish   193 TQFKVKHLVFRMYDVGGQRTERRKWISCFEYVRSVLFVVSLSGYDMTLVEDPSMNRLQESLKLFS 257

  Fly   251 NIISFSWFQHSSVILFLNKEDLFKKKILST--HLADYFPEYNGPKKDAKAAREFILYMFTSVNPD 313
            :|.:..:|:.:|:|||:||.|||::|||.:  ||..|.|::.|...|..||..||..||.|:|..
Zfish   258 SICNNIFFRGTSMILFMNKIDLFQEKILHSGRHLRHYLPQFRGADCDVDAAARFIADMFVSLNAS 322

  Fly   314 PYKCIYPHFTVATNTENIKFVFTAVKDTILELHLSETNLL 353
            |.|.||.|||.||:|.|::.||..|.|||::.:|...:||
Zfish   323 PSKLIYHHFTTATDTSNVQVVFQVVMDTIIKENLEAVSLL 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17760	NP_001036539.1	G_alpha	13..351	CDD:214595	137/349 (39%)
CG17760	NP_001036539.1	G-alpha	34..347	CDD:206639	130/319 (41%)
gnav1	NP_001159486.1	G_alpha	20..357	CDD:214595	135/339 (40%)
gnav1	NP_001159486.1	G-alpha	39..356	CDD:206639	130/319 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586278
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.760