DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17760 and gnai2a

DIOPT Version :9

Sequence 1:	NP_001036539.1	Gene:	CG17760 / 36385	FlyBaseID:	FBgn0033756	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_001001818.1	Gene:	gnai2a / 336421	ZFINID:	ZDB-GENE-030131-8365	Length:	355	Species:	Danio rerio

Alignment Length:	360	Identity:	165/360 - (45%)
Similarity:	227/360 - (63%)	Gaps:	14/360 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDCCLS--DQACEERRISREIDKFLKAEKKKARRELKLLVLGTGESGKTTFIKQMRIIHGKGFLD 63
            |.|.:|  |:|..||  |:.||:.|:.:.:||.:|:|||:||.|||||:|.:|||:|||..|:.:
Zfish     1 MGCTVSQEDKAALER--SKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSE 63

  Fly    64 KERKQFTKNVFQNIFMAIQSMISAMDTLRIPYGQQEHSKLADLVKSIDYKTVTRLEAPYL----- 123
            :|.||:...||.|...:|.:::.||.:|:|.|   |.|..||..:.:...:.|..|...|
Zfish    64 EECKQYRAVVFSNTIQSIMAIVKAMTSLKIEY---EDSARADDARQLFALSGTAEEQGILPDELA 125

  Fly   124 NAIKTLWKDAGIKECYNRRREYQLTDSTEYFLNDIARIERSDYQATDQDILHVRAPTTNIVEYPF 188
            |.|..||.|.|::.|:.|.|||||.||..|:|||:.||.::||..|.||:|..|..||.|||..|
Zfish   126 NVICRLWADRGVQNCFTRAREYQLNDSAAYYLNDMERIAKADYIPTQQDVLRTRVKTTGIVETHF 190

  Fly   189 NLDGFLIRLVDVAGQRTERRKWIHCFSNVTSIMFLVAMSEFDLSLAESENDNRMKESKALFHNII 253
            .......::.||.|||:||:||||||..||:|:|.||||.:||.|||.|..|||.||..||.:|.
Zfish   191 TFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVAMSAYDLVLAEDEEMNRMHESMKLFDSIC 255

  Fly   254 SFSWFQHSSVILFLNKEDLFKKKILSTHLADYFPEYNGPKKDAKAAREFILYMFTSVN-PDPYKC 317
            :..||..:|:||||||:|||::||..:.|...||||.| :.:.:.|.|:|...|..:| ....|.
Zfish   256 NNKWFTETSIILFLNKKDLFEQKITRSSLIICFPEYPG-EDNYEEASEYIRTKFEDLNKKKETKE 319

  Fly   318 IYPHFTVATNTENIKFVFTAVKDTILELHLSETNL 352
            ||||||.||:|:|::|||.||.|.|::.:|.:..|
Zfish   320 IYPHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGL 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17760	NP_001036539.1	G_alpha	13..351	CDD:214595	158/343 (46%)
CG17760	NP_001036539.1	G-alpha	34..347	CDD:206639	149/318 (47%)
gnai2a	NP_001001818.1	G_alpha	14..353	CDD:214595	159/344 (46%)
gnai2a	NP_001001818.1	G-alpha	34..349	CDD:206639	149/318 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.830