Protein Alignment CG17760 and GNA15

DIOPT Version :10

• Sequence 1: NP_001036539.1
• Gene: CG17760 / 36385
• FlyBaseID: FBgn0033756
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_002059.3
• Gene: GNA15 / 2769
• HGNCID: 4383
• Length: 374
• Species: Homo sapiens
• Alignment Length: 362
• Identity: 174/362 - (48%)
• Similarity: 247/362 - (68%)
• Gaps: 12/362 - (3%)

  Fly     4 CLSDQACEERRISREIDKFLKAEKKKARRELKLLVLGTGESGKTTFIKQMRIIHGKGFLDKERKQ 68
            ||::......|:.:||::.|..:||:.|.|||||:||.|||||:|||||||||||.|:.::|||.
Human    13 CLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKG 77

  Fly    69 FTKNVFQNIFMAIQSMISAMDTLRIPYGQQEHSKLADLVKSIDYKTVTRLEAPYLNAIKTLWKDA 133
            |...|:||||:::::||.||:.|:||:.:.|....|.||.|.|...||..|..|..|::.||:||
Human    78 FRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDA 142

  Fly   134 GIKECYNRRREYQLTDSTEYFLNDIARIERSDYQATDQDILHVRAPTTNIVEYPFNLDGFLIRLV 198
            ||:.||.||||:.|.||..|:|:.:.||....|..|.||:|..|.|||.|.||.|::....:|:|
Human   143 GIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIV 207

  Fly   199 DVAGQRTERRKWIHCFSNVTSIMFLVAMSEFDLSLAESENDNRMKESKALFHNIISFSWFQHSSV 263
            ||.||::||:||||||.||.::::|.::||:|..|.|:..:||||||.|||..|:...||:.:||
Human   208 DVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSV 272

  Fly   264 ILFLNKEDLFKKKILSTHLADYFPEYNGPKKDAKAAREFILYMFTSV------NPDPYK------ 316
            ||||||.|:.::||.::|||.|||.:.|||:||:||:.|||.|:|.:      .|:..|
Human   273 ILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSR 337

  Fly   317 CIYPHFTVATNTENIKFVFTAVKDTILELHLSETNLL 353
            .::.|:|.||:|:||:.||..|:|::|..:|.|.|||
Human   338 RLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17760	NP_001036539.1	G-alpha	34..347	CDD:206639	159/324 (49%)
GNA15	NP_002059.3	G_alpha	22..372	CDD:214595	169/349 (48%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	44..57		10/12 (83%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	181..189		3/7 (43%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	204..213		5/8 (63%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	273..280		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	344..349		3/4 (75%)