DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17760 and Gnat3

DIOPT Version :9

Sequence 1:	NP_001036539.1	Gene:	CG17760 / 36385	FlyBaseID:	FBgn0033756	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_001074612.1	Gene:	Gnat3 / 242851	MGIID:	3588268	Length:	354	Species:	Mus musculus

Alignment Length:	354	Identity:	145/354 - (40%)
Similarity:	216/354 - (61%)	Gaps:	11/354 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LSDQACEERRISREIDKFLKAEKKKARRELKLLVLGTGESGKTTFIKQMRIIHGKGFLDKERKQF 69
            :|.::.|..|.|:|::|.|:.:.::..|.:|||:||.|||||:|.:|||:|||..|:..:|..:|
Mouse     5 ISSESKESARRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSKQECMEF 69

  Fly    70 TKNVFQNIFMAIQSMISAMDTLRIPY----GQQEHSKLADLVKSIDYKTVTRLEAPYL-NAIKTL 129
            ...::.|...:|.:::.||.||.|.|    .:::..:|..:..:::...:|    |.| ..||.|
Mouse    70 KAVIYSNTLQSILAIVKAMATLGIDYVNPRSREDQEQLHSMANTLEDGDMT----PQLAEIIKRL 130

  Fly   130 WKDAGIKECYNRRREYQLTDSTEYFLNDIARIERSDYQATDQDILHVRAPTTNIVEYPFNLDGFL 194
            |.|.||:.|:.|..||||.||..|:|||:.|:....|...:||:||.|..||.|:|..|:.....
Mouse   131 WGDPGIQACFERASEYQLNDSAAYYLNDLDRLTAPGYVPNEQDVLHSRVKTTGIIETQFSFKDLN 195

  Fly   195 IRLVDVAGQRTERRKWIHCFSNVTSIMFLVAMSEFDLSLAESENDNRMKESKALFHNIISFSWFQ 259
            .|:.||.|||:||:||||||..||.|:|..|:|.:|:.|.|.|..|||.||..||::|.:..:|.
Mouse   196 FRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFA 260

  Fly   260 HSSVILFLNKEDLFKKKILSTHLADYFPEYNGPKKDAKAAREFILYMFTSVN-PDPYKCIYPHFT 323
            .:|::|||||:|||::|:...||:..||||.|| ...:.|..:|...|..:| ....|.||.|.|
Mouse   261 TTSIVLFLNKKDLFQEKVAKVHLSICFPEYTGP-NTFEDAGNYIKNQFLDLNLKKEDKEIYSHMT 324

  Fly   324 VATNTENIKFVFTAVKDTILELHLSETNL 352
            .||:|:|:||||.||.|.|::.:|.:..|
Mouse   325 CATDTQNVKFVFDAVTDIIIKENLKDCGL 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17760	NP_001036539.1	G_alpha	13..351	CDD:214595	142/343 (41%)
CG17760	NP_001036539.1	G-alpha	34..347	CDD:206639	135/318 (42%)
Gnat3	NP_001074612.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26		7/20 (35%)
		G_alpha	13..352	CDD:214595	142/343 (41%)
		G-alpha	34..348	CDD:206639	135/318 (42%)
		G1 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	35..48		10/12 (83%)
		G2 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	173..181		4/7 (57%)
		G3 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	196..205		4/8 (50%)
		G4 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	265..272		5/6 (83%)
		G5 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	324..329		3/4 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841798
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.760