DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17760 and gpa-2

DIOPT Version :9

Sequence 1:	NP_001036539.1	Gene:	CG17760 / 36385	FlyBaseID:	FBgn0033756	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_505157.1	Gene:	gpa-2 / 179219	WormBaseID:	WBGene00001664	Length:	356	Species:	Caenorhabditis elegans

Alignment Length:	363	Identity:	132/363 - (36%)
Similarity:	205/363 - (56%)	Gaps:	19/363 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDCCLSDQACEERRI----SREIDKFLKAEKKKARRELKLLVLGTGESGKTTFIKQMRIIHGKGF 61
            |..|.|    ||.::    ||.|||.:|..:....|.:|||:||.||.||:|.:||||::..|.:
Worm     1 MGLCQS----EEEKVGTLKSRAIDKEIKQLQTSEERTVKLLLLGAGECGKSTVLKQMRLLTSKQY 61

  Fly    62 LDKERKQFTKNVFQNIFMAIQSMISAMDTLRIPYG--QQEHS--KLADLVKSIDYKTVTRLEAPY 122
            .|:|.....|.|:.||.:.:..::.||....:.:.  .:||.  .|...:|.:.:|...:..|.:
Worm    62 TDEELLTQAKLVYTNIVIEMDHLVKAMPAAGLNFSDPMREHDVHMLTLYIKDMQHKNFQQDAADH 126

  Fly   123 LNAIKTLWKDAGIKECYNRRREYQLT---DSTEYFLNDIARIERSDYQATDQDILHVRAPTTNIV 184
               ::.||||..:|..|..|:|..:.   |:||||..::.||.:.||.....|.|.:|..||.||
Worm   127 ---VEKLWKDPVVKRLYAERKELNIRDIGDNTEYFFENLPRISKEDYHPNATDTLLLRTKTTGIV 188

  Fly   185 EYPFNLDGFLIRLVDVAGQRTERRKWIHCFSNVTSIMFLVAMSEFDLSLAESENDNRMKESKALF 249
            |..|.:.....|:.||.|||:||:||||||.:|.:|:|:.|:||::..|.|.|..|||.||..||
Worm   189 EVGFEIKKVKFRVFDVGGQRSERKKWIHCFEDVNAIIFIAALSEYNEVLFEDETTNRMIESMRLF 253

  Fly   250 HNIISFSWFQHSSVILFLNKEDLFKKKILSTHLADYFPEYNGPKKDAKAAREFILYMFTSVNPDP 314
            .:|.:..||.::::||||||:|||::||...::...||||.|.:..|:.. .||...|.:::.:|
Worm   254 ESICNSRWFHNTNIILFLNKKDLFEEKIKKENIHKAFPEYRGEQNYAETV-AFIKTKFEALSNNP 317

  Fly   315 YKCIYPHFTVATNTENIKFVFTAVKDTILELHLSETNL 352
            .|..|.|.|.||:|..::.:..:|...|::.:|.::.|
Worm   318 KKTFYVHETCATDTNQVQKILDSVISMIIQSNLHKSGL 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17760	NP_001036539.1	G_alpha	13..351	CDD:214595	126/348 (36%)
CG17760	NP_001036539.1	G-alpha	34..347	CDD:206639	118/319 (37%)
gpa-2	NP_505157.1	G_alpha	13..354	CDD:214595	126/344 (37%)
gpa-2	NP_505157.1	G-alpha	34..350	CDD:206639	118/319 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162144
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.760