DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17760 and goa-1

DIOPT Version :9

Sequence 1:	NP_001036539.1	Gene:	CG17760 / 36385	FlyBaseID:	FBgn0033756	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_492108.1	Gene:	goa-1 / 172505	WormBaseID:	WBGene00001648	Length:	354	Species:	Caenorhabditis elegans

Alignment Length:	355	Identity:	159/355 - (44%)
Similarity:	225/355 - (63%)	Gaps:	15/355 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDCCLS--DQACEERRISREIDKFLKAEKKKARRELKLLVLGTGESGKTTFIKQMRIIHGKGFLD 63
            |.|.:|  ::|..||  ||.|:|.||.:..:|.:::|||:||.|||||:|.:|||:|||..||..
Worm     1 MGCTMSQEERAALER--SRMIEKNLKEDGMQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTA 63

  Fly    64 KERKQFTKNVFQNIFMAIQSMISAMDTLRIPYGQQEHSKLADLVKSIDYKTVTRLE--APY---- 122
            ::.||:...|:.|...::.:::.||..|.:.:|..:....|.||..:    |.|:|  .|:
Worm    64 EDYKQYKPVVYSNTVQSLVAILRAMSNLGVSFGSADREVDAKLVMDV----VARMEDTEPFSEEL 124

  Fly   123 LNAIKTLWKDAGIKECYNRRREYQLTDSTEYFLNDIARIERSDYQATDQDILHVRAPTTNIVEYP 187
            |:::|.||.|||:::|::|..||||.||.:|||:|:.|:..:.||.|:||||..|..||.|||..
Worm   125 LSSMKRLWGDAGVQDCFSRSNEYQLNDSAKYFLDDLERLGEAIYQPTEQDILRTRVKTTGIVEVH 189

  Fly   188 FNLDGFLIRLVDVAGQRTERRKWIHCFSNVTSIMFLVAMSEFDLSLAESENDNRMKESKALFHNI 252
            |.......:|.||.|||:||:||||||.:||:|:|.|||||:|..|.|.|..|||.||..||.:|
Worm   190 FTFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMHESLKLFDSI 254

  Fly   253 ISFSWFQHSSVILFLNKEDLFKKKILSTHLADYFPEYNGPKKDAKAAREFILYMFTSVNPDPYKC 317
            .:..||..:|:||||||:|||::||..:.|...||||:| ::|...|..:|...|.:.|....|.
Worm   255 CNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICFPEYSG-RQDYHEASAYIQAQFEAKNKSANKE 318

  Fly   318 IYPHFTVATNTENIKFVFTAVKDTILELHL 347
            ||.|.|.||:|.||:|||.||.|.|:..:|
Worm   319 IYCHMTCATDTTNIQFVFDAVTDVIIANNL 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17760	NP_001036539.1	G_alpha	13..351	CDD:214595	154/341 (45%)
CG17760	NP_001036539.1	G-alpha	34..347	CDD:206639	145/318 (46%)
goa-1	NP_492108.1	G_alpha	14..352	CDD:214595	155/342 (45%)
goa-1	NP_492108.1	G-alpha	34..348	CDD:206639	145/318 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.830