DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17760 and gpa-14

DIOPT Version :9

Sequence 1:	NP_001036539.1	Gene:	CG17760 / 36385	FlyBaseID:	FBgn0033756	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_001020966.2	Gene:	gpa-14 / 172269	WormBaseID:	WBGene00001676	Length:	408	Species:	Caenorhabditis elegans

Alignment Length:	362	Identity:	112/362 - (30%)
Similarity:	180/362 - (49%)	Gaps:	28/362 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RRISREIDKFLKAEKKKARRELKLLVLGTGESGKTTFIKQMRIIHGKGF-LDKERKQFTKNVFQN 76
            ||...||:|.|..|||.....:|:|:||...|||:|..|||:|||..|| .|:|..|:...:..|
Worm    52 RRGHMEIEKELALEKKTYGSHIKILILGGPLSGKSTIFKQMQIIHVDGFKTDQELIQYRGLIDNN 116

  Fly    77 IFMAIQSMISAMDTLRIPYGQQEH------SKLADLVKSIDYKTVTRLEAPYLNAIKTLWKDAGI 135
            |......:|:....:.||....||      ...|.:..:...:|::.|    |..:...|....|
Worm   117 IRDIYLQLIAGSRVVGIPLDPIEHITYEIDEIYAPMSDAFSVRTISEL----LEPLTEFWNSKQI 177

  Fly   136 KECYNRRREYQLTDSTEYFLNDIARIERSDYQATDQDILHVRAPTTNIVEYPFNLDGFLIRLVDV 200
            :|.|.||.|::|.|||:|:|.::.||....|....:||:|.|..|.:|....|...|..:.::||
Worm   178 QEIYKRRCEFELLDSTKYYLENLTRIADPTYLPNQEDIVHSRKATMSINSIVFEYTGVSLLMIDV 242

  Fly   201 AGQRTERRKWIHCFSNVTSIMFLVAMSEFDLSLAES---------------ENDNRMKESKALFH 250
            .|||:||:||:|.|.:...::|::.::.:.....||               .|...||.:..:|:
Worm   243 GGQRSERKKWLHLFDDAKVVLFVIDLTGYAKRSEESRMELSRFPKFFRDVGSNAYDMKVALKIFN 307

  Fly   251 NIISFSWFQHSSVILFLNKEDLFKKKILSTHLADYFPEYNGPKKDAKAAREFILYMFTSVNPDPY 315
            .:.:.|...::..:||.||.||||:.:...:|...|.:::| :...:...::|...|... ....
Worm   308 EVAAASALANAVFLLFFNKVDLFKEILSQVNLQPCFSKFDG-ENTYEETSKYICEKFIRA-ASSK 370

  Fly   316 KCIYPHFTVATNTENIKFVFTAVKDTILELHLSETNL 352
            |.::||||.||||||:|.||.|..:::.:.:...|.|
Worm   371 KSVFPHFTTATNTENVKLVFRACMESVFKANAKATGL 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17760	NP_001036539.1	G_alpha	13..351	CDD:214595	110/359 (31%)
CG17760	NP_001036539.1	G-alpha	34..347	CDD:206639	101/334 (30%)
gpa-14	NP_001020966.2	G_alpha	52..406	CDD:214595	110/359 (31%)
gpa-14	NP_001020966.2	G-alpha	73..401	CDD:206639	101/333 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162150
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.860