DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17760 and egl-30

DIOPT Version :9

Sequence 1:	NP_001036539.1	Gene:	CG17760 / 36385	FlyBaseID:	FBgn0033756	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_740789.1	Gene:	egl-30 / 171751	WormBaseID:	WBGene00001196	Length:	355	Species:	Caenorhabditis elegans

Alignment Length:	355	Identity:	220/355 - (61%)
Similarity:	289/355 - (81%)	Gaps:	2/355 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDCCLSDQACEERRISREIDKFLKAEKKKARRELKLLVLGTGESGKTTFIKQMRIIHGKGFLDKE 65
            |.||||::|.|::||::||:|.|:.:|:.||||||||:||||||||:|||||||||||:|:.:::
Worm     1 MACCLSEEAREQKRINQEIEKQLQRDKRNARRELKLLLLGTGESGKSTFIKQMRIIHGQGYSEED 65

  Fly    66 RKQFTKNVFQNIFMAIQSMISAMDTLRIPYG--QQEHSKLADLVKSIDYKTVTRLEAPYLNAIKT 128
            ::...:.|:||:||||||||.|||||.|.:|  .:|..:.|.:|:.:|:::||..|.||::.||.
Worm    66 KRAHIRLVYQNVFMAIQSMIRAMDTLDIKFGNESEELQEKAAVVREVDFESVTSFEEPYVSYIKE 130

  Fly   129 LWKDAGIKECYNRRREYQLTDSTEYFLNDIARIERSDYQATDQDILHVRAPTTNIVEYPFNLDGF 193
            ||:|:||:|||:||||||||||.:|:|:|:.|:...||..|:||||.||.|||.|:||||:|:..
Worm   131 LWEDSGIQECYDRRREYQLTDSAKYYLSDLRRLAVPDYLPTEQDILRVRVPTTGIIEYPFDLEQI 195

  Fly   194 LIRLVDVAGQRTERRKWIHCFSNVTSIMFLVAMSEFDLSLAESENDNRMKESKALFHNIISFSWF 258
            :.|:|||.|||:|||||||||.||||||||||:||:|..|.|.:|:|||:||||||..||::.||
Worm   196 IFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVECDNENRMEESKALFRTIITYPWF 260

  Fly   259 QHSSVILFLNKEDLFKKKILSTHLADYFPEYNGPKKDAKAAREFILYMFTSVNPDPYKCIYPHFT 323
            .:|||||||||:||.::|||.:|||||||||:||.:|..|||||||.||..:|||..|.||.|||
Worm   261 TNSSVILFLNKKDLLEEKILYSHLADYFPEYDGPPRDPIAAREFILKMFVDLNPDADKIIYSHFT 325

  Fly   324 VATNTENIKFVFTAVKDTILELHLSETNLL 353
            .||:||||:|||.|||||||:.:|.|.||:
Worm   326 CATDTENIRFVFAAVKDTILQHNLKEYNLV 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17760	NP_001036539.1	G_alpha	13..351	CDD:214595	211/339 (62%)
CG17760	NP_001036539.1	G-alpha	34..347	CDD:206639	198/314 (63%)
egl-30	NP_740789.1	G_alpha	13..353	CDD:214595	211/339 (62%)
egl-30	NP_740789.1	G-alpha	34..349	CDD:206639	198/314 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S445
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D373878at33208
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.880