DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17760 and gpa-16

DIOPT Version :9

Sequence 1:	NP_001036539.1	Gene:	CG17760 / 36385	FlyBaseID:	FBgn0033756	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_490790.1	Gene:	gpa-16 / 171675	WormBaseID:	WBGene00001678	Length:	357	Species:	Caenorhabditis elegans

Alignment Length:	359	Identity:	149/359 - (41%)
Similarity:	218/359 - (60%)	Gaps:	10/359 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDCCLSDQACEERRISREIDKFLKAEKKKARRELKLLVLGTGESGKTTFIKQMRIIHGKGFLDKE 65
            |.|.:|.:....:|.|::||:.||.:.:.:.|.:|||:||.|||||:|.:|||||||..|:..:|
Worm     1 MGCIMSQEDEAAKRRSKKIDRLLKEDGENSMRTIKLLLLGAGESGKSTILKQMRIIHDVGYTTEE 65

  Fly    66 RKQFTKNVFQNIFMAIQSMISAMDTLRIPYGQQEHSKLADLVKSIDYKTV---TRLEAPYLNAIK 127
            ||.|...|:.||.:::.::|.||:.|:|.:...:|.  :|..|.:.:.|.   ..|....:..:|
Worm    66 RKVFRGVVYGNIILSLNAIIHAMEQLKISFTTLDHE--SDARKLLMFSTTGEEDELPEELVVLMK 128

  Fly   128 TLWKDAGIKECYNRRREYQLTDSTEYFLNDIARIERSDYQATDQDILHVRAPTTNIVEYPFNLDG 192
            ::|.|:||::...|.|||||.||..|:|:.:.||...:|..|..|||..|..||.|||..|....
Worm   129 SVWSDSGIQKALERSREYQLNDSAGYYLSQLDRICAPNYIPTQDDILRTRIKTTGIVETQFVYKD 193

  Fly   193 FLIRLVDVAGQRTERRKWIHCFSNVTSIMFLVAMSEFDLSLAESENDNRMKESKALFHNIISFSW 257
            .|..:.||.|||:||:||||||.:||:::|.||:||:|:.|.|....|||:||..||.:|.:..|
Worm   194 RLFLVFDVGGQRSERKKWIHCFEDVTALIFCVALSEYDMVLVEDCQTNRMRESLKLFDSICNNKW 258

  Fly   258 FQHSSVILFLNKEDLFKKKILSTHLADYFPEYNGPKKDAKAAREFILYMFTSVNP----DPYKCI 318
            |..:|:||||||:|||::||:.:.|...||||.| ..:.:.|..:|...|..:|.    :..:.|
Worm   259 FVETSIILFLNKKDLFEEKIVRSPLTHCFPEYTG-ANNYEEASAYIQQQFEDMNKRTTGEKNQEI 322

  Fly   319 YPHFTVATNTENIKFVFTAVKDTILELHLSETNL 352
            |..||.||:|.||:|||.||.|.|:..:|....|
Worm   323 YTQFTCATDTNNIRFVFDAVTDIIIRDNLRTCGL 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17760	NP_001036539.1	G_alpha	13..351	CDD:214595	145/344 (42%)
CG17760	NP_001036539.1	G-alpha	34..347	CDD:206639	137/319 (43%)
gpa-16	NP_490790.1	G_alpha	13..355	CDD:214595	145/344 (42%)
gpa-16	NP_490790.1	G-alpha	34..351	CDD:206639	137/319 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.830