Protein Alignment CG17760 and Gnas

DIOPT Version :10

• Sequence 1: NP_001036539.1
• Gene: CG17760 / 36385
• FlyBaseID: FBgn0033756
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_034439.2
• Gene: Gnas / 14683
• MGIID: 95777
• Length: 1133
• Species: Mus musculus
• Alignment Length: 387
• Identity: 141/387 - (36%)
• Similarity: 213/387 - (55%)
• Gaps: 42/387 - (10%)

  Fly     5 LSDQACEERRISREIDKFLKAEKKKARRELKLLVLGTGESGKTTFIKQMRIIHGKGF-------- 61
            :.:|...:::.|:.|||.|:.||.......:||:||.|||||:|.:|||||:|..||
Mouse   751 MREQKRADKKRSKLIDKQLEEEKMDYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEED 815

  Fly    62 -------LDKERKQFTKNVFQNIFMAIQSMISAMDTLRIP--YGQQEHSKLADLVKSIDYKTVTR 117
                   .|.|:....:::..|:..||:::::||..|..|  ....|:....|.:.|:  ..|..
Mouse   816 PQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSV--MNVPN 878

  Fly   118 LEAP--YLNAIKTLWKDAGIKECYNRRREYQLTDSTEYFLNDIARIERSDYQATDQDILHVRAPT 180
            .:.|  :....|.||:|.|::.||.|..||||.|..:|||:.|..|:::||..:|||:|..|..|
Mouse   879 FDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLT 943

  Fly   181 TNIVEYPFNLDGFLIRLVDVAGQRTERRKWIHCFSNVTSIMFLVAMSEFDLSLAESENDNRMKES 245
            :.|.|..|.:|.....:.||.|||.||||||.||::||:|:|:||.|.:::.:.|....||::|:
Mouse   944 SGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEA 1008

  Fly   246 KALFHNIISFSWFQHSSVILFLNKEDLFKKKILS--THLADYFPEY----------NGPKKDAKA 298
            ..||.:|.:..|.:..||||||||:||..:|:|:  :.:.|||||:          ..|.:|.:.
Mouse  1009 LNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRV 1073

  Fly   299 AR-------EFILYMFTSVNPDPYKCIYPHFTVATNTENIKFVFTAVKDTILELHLSETNLL 353
            .|       || |.:.|:.....:.| |||||.|.:||||:.||...:|.|..:||.:..||
Mouse  1074 TRAKYFIRDEF-LRISTASGDGRHYC-YPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL 1133

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17760	NP_001036539.1	G-alpha	34..347	CDD:206639	129/350 (37%)
Gnas	NP_034439.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..195
		PHA03247	<50..496	CDD:223021
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	322..552
		PRK12323	<330..531	CDD:481241
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	611..648
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	724..744
		UDM1_RNF168_RNF169-like	730..>772	CDD:409016	6/20 (30%)
		G-alpha	780..1127	CDD:206639	129/350 (37%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	781..794		9/12 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	807..828		3/20 (15%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	935..943		3/7 (43%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	958..967		3/8 (38%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	1027..1034		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	1103..1108		2/4 (50%)