DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17760 and Gnao1

DIOPT Version :9

Sequence 1:	NP_001036539.1	Gene:	CG17760 / 36385	FlyBaseID:	FBgn0033756	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_001106855.1	Gene:	Gnao1 / 14681	MGIID:	95775	Length:	354	Species:	Mus musculus

Alignment Length:	355	Identity:	161/355 - (45%)
Similarity:	223/355 - (62%)	Gaps:	15/355 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDCCLS--DQACEERRISREIDKFLKAEKKKARRELKLLVLGTGESGKTTFIKQMRIIHGKGFLD 63
            |.|.||  ::|..||  |:.|:|.||.:...|.:::|||:||.|||||:|.:|||:|||..||..
Mouse     1 MGCTLSAEERAALER--SKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSG 63

  Fly    64 KERKQFTKNVFQNIFMAIQSMISAMDTLRIPYGQQEHSKLADLVKSIDYKTVTRLE------APY 122
            ::.||:...|:.|...::.:::.|||||.:.||.:|....:.:|..:    |:|:|      |..
Mouse    64 EDVKQYKPVVYSNTIQSLAAIVRAMDTLGVEYGDKERKTDSKMVCDV----VSRMEDTEPFSAEL 124

  Fly   123 LNAIKTLWKDAGIKECYNRRREYQLTDSTEYFLNDIARIERSDYQATDQDILHVRAPTTNIVEYP 187
            |:|:..||.|:||:||:||.|||||.||.:|:|:.:.||...|||.|:||||..|..||.|||..
Mouse   125 LSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAGDYQPTEQDILRTRVKTTGIVETH 189

  Fly   188 FNLDGFLIRLVDVAGQRTERRKWIHCFSNVTSIMFLVAMSEFDLSLAESENDNRMKESKALFHNI 252
            |.......||.||.|||:||:||||||.:||:|:|.||:|.:|..|.|.|..|||.||..||.:|
Mouse   190 FTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLKLFDSI 254

  Fly   253 ISFSWFQHSSVILFLNKEDLFKKKILSTHLADYFPEYNGPKKDAKAAREFILYMFTSVNPDPYKC 317
            .:..||..:|:||||||:|:|::||..:.|...||||.||....:|... |...:.|.|...:|.
Mouse   255 CNNKWFTDTSIILFLNKKDIFEEKIKKSPLTICFPEYTGPSAFTEAVAH-IQGQYESKNKSAHKE 318

  Fly   318 IYPHFTVATNTENIKFVFTAVKDTILELHL 347
            :|.|.|.||:|.||:|||.||.|.|:..:|
Mouse   319 VYSHVTCATDTNNIQFVFDAVTDVIIAKNL 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17760	NP_001036539.1	G_alpha	13..351	CDD:214595	155/341 (45%)
CG17760	NP_001036539.1	G-alpha	34..347	CDD:206639	147/318 (46%)
Gnao1	NP_001106855.1	G_alpha	14..352	CDD:214595	156/342 (46%)
Gnao1	NP_001106855.1	G-alpha	34..348	CDD:206639	147/318 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.930