DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17760 and Gna13

DIOPT Version :9

Sequence 1:	NP_001036539.1	Gene:	CG17760 / 36385	FlyBaseID:	FBgn0033756	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_034433.3	Gene:	Gna13 / 14674	MGIID:	95768	Length:	377	Species:	Mus musculus

Alignment Length:	359	Identity:	147/359 - (40%)
Similarity:	221/359 - (61%)	Gaps:	9/359 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 CCLSDQACEERRISREIDKFLKAEKKKARRELKLLVLGTGESGKTTFIKQMRIIHGKGFLDKERK 67
            |.|::...|::|.|:||||.|..||...:|.:|:|:||.|||||:||:||||||||:.|..:.|:
Mouse    18 CVLTNGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRARE 82

  Fly    68 QFTKNVFQNIFMAIQSMISAMDTLRIPYGQQEHSKLADLVKSIDYK--------TVTRLEAPYLN 124
            :|...::.|:...::.::.|.:.|.||:|..::....|.:.:.|.:        ..||:...||.
Mouse    83 EFRPTIYSNVIKGMRVLVDAREKLHIPWGDNKNQLHGDKLMAFDTRAPMAAQGMVETRVFLQYLP 147

  Fly   125 AIKTLWKDAGIKECYNRRREYQLTDSTEYFLNDIARIERSDYQATDQDILHVRAPTTNIVEYPFN 189
            ||:.||:|:||:..|:||||:||.:|.:|||:::.::...||..:.||||..|.||..|.||.|.
Mouse   148 AIRALWEDSGIQNAYDRRREFQLGESVKYFLDNLDKLGVPDYIPSQQDILLARRPTKGIHEYDFE 212

  Fly   190 LDGFLIRLVDVAGQRTERRKWIHCFSNVTSIMFLVAMSEFDLSLAESENDNRMKESKALFHNIIS 254
            :.....::|||.|||:||::|..||.:||||:|||:.||||..|.|....||:.||..:|..|::
Mouse   213 IKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRQTNRLTESLNIFETIVN 277

  Fly   255 FSWFQHSSVILFLNKEDLFKKKILSTHLADYFPEYNGPKKDAKAAREFILYMFTSVNPD-PYKCI 318
            ...|.:.|:||||||.||.::|:....:.|||.|:.|.....:..::|::..|.....| ..:.:
Mouse   278 NRVFSNVSIILFLNKTDLLEEKVQVVSIKDYFLEFEGDPHCLRDVQKFLVECFRGKRRDQQQRPL 342

  Fly   319 YPHFTVATNTENIKFVFTAVKDTILELHLSETNL 352
            |.|||.|.|||||:.||..||||||..:|.:..|
Mouse   343 YHHFTTAINTENIRLVFRDVKDTILHDNLKQLML 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17760	NP_001036539.1	G_alpha	13..351	CDD:214595	143/346 (41%)
CG17760	NP_001036539.1	G-alpha	34..347	CDD:206639	132/321 (41%)
Gna13	NP_034433.3	G_alpha	29..375	CDD:214595	143/345 (41%)
		G-alpha	49..371	CDD:206639	132/321 (41%)
		G1 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	50..63		9/12 (75%)
		G2 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	195..203		4/7 (57%)
		G3 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	218..227		4/8 (50%)
		G4 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	287..294		6/6 (100%)
		G5 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	347..352		2/4 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841813
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.760