DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17760 and gnat2

DIOPT Version :9

Sequence 1:	NP_001036539.1	Gene:	CG17760 / 36385	FlyBaseID:	FBgn0033756	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_571944.1	Gene:	gnat2 / 140429	ZFINID:	ZDB-GENE-011128-10	Length:	354	Species:	Danio rerio

Alignment Length:	358	Identity:	147/358 - (41%)
Similarity:	222/358 - (62%)	Gaps:	18/358 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SDQACEERRI---SREIDKFLKAEKKKARRELKLLVLGTGESGKTTFIKQMRIIHGKGFLDKERK 67
            |..:.|::.:   |:|::|.|:.:..|..:.:|||:||.|||||:|.:|||:|:|..|:..:|:.
Zfish     3 SGASAEDKEMAKKSKELEKQLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKILHQGGYTKEEQM 67

  Fly    68 QFTKNVFQNIFMAIQSMISAMDTLRIPYG----QQEHSKLADLVKSIDYKTVTRLEAPYL-NAIK 127
            :|...:|.||..:..::|..|:.|.|.:|    |::..||.:|..||:..|:    .|.| :.||
Zfish    68 EFRSIIFGNILQSALAIIRGMEMLSINFGSPSAQEDSQKLQNLSDSIEEGTM----PPELADVIK 128

  Fly   128 TLWKDAGIKECYNRRREYQLTDSTEYFLNDIARIERSDYQATDQDILHVRAPTTNIVEYPFNLDG 192
            .||||||::..::|..||||.||..|:||::.||.:.||..|:||:|..|..||.|:|..|....
Zfish   129 RLWKDAGVQASFDRAAEYQLNDSAGYYLNEMDRICKPDYLPTEQDVLRSRVKTTGIIEEQFGCKE 193

  Fly   193 FLIRLVDVAGQRTERRKWIHCFSNVTSIMFLVAMSEFDLSLAESENDNRMKESKALFHNIISFSW 257
            ...|:.||.|||:||:||||||..||.|:|..|:|.:|:.|.|.:..|||.||..||::|.:..:
Zfish   194 LHFRMFDVGGQRSERKKWIHCFEGVTCIIFCGALSAYDMVLVEDDEVNRMHESLHLFNSICNHRF 258

  Fly   258 FQHSSVILFLNKEDLFKKKILSTHLADYFPEYNGPK--KDAKAAREFILYMFTSVN-PDPYKCIY 319
            |..:|::|||||:|||::||...||:..||:|:||.  :||.   .:|...|..:| ....|.||
Zfish   259 FATTSIVLFLNKKDLFQEKIKKVHLSICFPDYDGPNTYEDAS---NYIKTQFQDLNMKKGVKEIY 320

  Fly   320 PHFTVATNTENIKFVFTAVKDTILELHLSETNL 352
            .|.|.||:|:|::.||.||.|.|::.:|.:..|
Zfish   321 SHMTCATDTKNVEIVFNAVTDIIIKENLKDCGL 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17760	NP_001036539.1	G_alpha	13..351	CDD:214595	144/348 (41%)
CG17760	NP_001036539.1	G-alpha	34..347	CDD:206639	138/320 (43%)
gnat2	NP_571944.1	G_alpha	13..352	CDD:214595	144/345 (42%)
gnat2	NP_571944.1	G-alpha	34..348	CDD:206639	138/320 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830