DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17760 and gnai3

DIOPT Version :9

Sequence 1:	NP_001036539.1	Gene:	CG17760 / 36385	FlyBaseID:	FBgn0033756	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_001104720.1	Gene:	gnai3 / 100006888	ZFINID:	ZDB-GENE-070713-6	Length:	354	Species:	Danio rerio

Alignment Length:	359	Identity:	161/359 - (44%)
Similarity:	221/359 - (61%)	Gaps:	13/359 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDCCLS--DQACEERRISREIDKFLKAEKKKARRELKLLVLGTGESGKTTFIKQMRIIHGKGFLD 63
            |.|.||  |:|..|:  |:.||:.|:.:.:||.||:|||:||.|||||:|.:|||:|||..|:.:
Zfish     1 MGCTLSTEDKAAMEK--SKMIDRTLREDGEKASREVKLLLLGAGESGKSTIVKQMKIIHEDGYSE 63

  Fly    64 KERKQFTKNVFQNIFMAIQSMISAMDTLRIPYGQ----QEHSKLADLVKSIDYKTVTRLEAPYLN 124
            .|.||:...|:.|...:|.::|.||..|:|.:|.    .:..:|..|..:.:...:|   |....
Zfish    64 DECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGDPARADDARQLFVLAGTAEEGVMT---ADLSG 125

  Fly   125 AIKTLWKDAGIKECYNRRREYQLTDSTEYFLNDIARIERSDYQATDQDILHVRAPTTNIVEYPFN 189
            .|:.||||.|::.|:.|.|||||.||..|:|||:.||.:..|..|.||:|..|..||.|||..|.
Zfish   126 VIRRLWKDEGVQMCFVRSREYQLNDSAAYYLNDLERISQPTYTPTQQDVLRTRVKTTGIVETHFT 190

  Fly   190 LDGFLIRLVDVAGQRTERRKWIHCFSNVTSIMFLVAMSEFDLSLAESENDNRMKESKALFHNIIS 254
            ......::.||.|||:||:||||||..||:|:|.||:|::||.|||.|..|||.||..||.:|.:
Zfish   191 FKELYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICN 255

  Fly   255 FSWFQHSSVILFLNKEDLFKKKILSTHLADYFPEYNGPKKDAKAAREFILYMFTSVNP-DPYKCI 318
            ..||..:||||||||:|||:.||..:.|...:|||.|.....:|| .:|...|..:|. ...|.|
Zfish   256 NKWFTDTSVILFLNKKDLFEDKIKKSPLTICYPEYCGTCTYEEAA-AYIQCQFEDLNKRKETKEI 319

  Fly   319 YPHFTVATNTENIKFVFTAVKDTILELHLSETNL 352
            |.|||.||:|:|::|||.||.|.|::.:|.|..|
Zfish   320 YTHFTCATDTKNVQFVFDAVTDVIIKNNLIECGL 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17760	NP_001036539.1	G_alpha	13..351	CDD:214595	153/342 (45%)
CG17760	NP_001036539.1	G-alpha	34..347	CDD:206639	143/317 (45%)
gnai3	NP_001104720.1	G_alpha	14..352	CDD:214595	154/343 (45%)
gnai3	NP_001104720.1	G-alpha	34..348	CDD:206639	143/317 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.830