Protein Alignment Galphaq and Gnaq

DIOPT Version :10

• Sequence 1: NP_725192.2
• Gene: Galphaq / 36384
• FlyBaseID: FBgn0004435
• Length: 396
• Species: Drosophila melanogaster
• Sequence 2: NP_112298.2
• Gene: Gnaq / 81666
• RGDID: 620770
• Length: 359
• Species: Rattus norvegicus
• Alignment Length: 395
• Identity: 292/395 - (73%)
• Similarity: 320/395 - (81%)
• Gaps: 43/395 - (10%)

  Fly     1 MECCLSEEAKEQKRINQEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDED 65
            |.|||||||||.:|||.|||:||||||||||||||||||||||||||||||||||||||||||||
  Rat     7 MACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDED 71

  Fly    66 KRGYIKLVFQNIFMAMQSMIKAMDMLKISYGQGEHSELADLVMSIDYETVTTFEDPYLNAIKTLW 130
            |||:.|||:||||.|||:||:|||.|||.|....:...|.||..:|.|.|:.||:||::|||:||
  Rat    72 KRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENPYVDAIKSLW 136

  Fly   131 DDAGIQECYDRRREYQLTDSAKYYLKDLDRVAQPAYLPTEQDILRVRVPTTGIIEYPFDLEEIRF 195
            :|.||||||||||||||:||.||||.||||||.|:||||:||:|||||||||||||||||:
  Rat   137 NDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVLRVRVPTTGIIEYPFDLQ---- 197

  Fly   196 SYLSDLARIEQADYLPTEQDILRARVPTTGILEYPFDLDGIVFRMVDVGGQRSERRKWIHCFENV 260
                                                   .::|||||||||||||||||||||||
  Rat   198 ---------------------------------------SVIFRMVDVGGQRSERRKWIHCFENV 223

  Fly   261 TSIIFLVALSEYDQILFESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHL 325
            |||:||||||||||:|.||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   224 TSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHL 288

  Fly   326 VDYFPEYDGPQRDAITAREFILRMFVDLNPDSEKIIYSHFTCATDTENIKLVFCAVKDTIMQNAL 390
            ||||||||||||||..||||||:|||||||||:||||||||||||||||:.||.||||||:|..|
  Rat   289 VDYFPEYDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNL 353

  Fly   391 KEFNL 395
            ||:||
  Rat   354 KEYNL 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphaq	NP_725192.2	G-alpha	34..390	CDD:206639	259/355 (73%)
Gnaq	NP_112298.2	G-alpha	40..353	CDD:206639	259/355 (73%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	41..54		12/12 (100%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	178..186		6/7 (86%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	201..210		8/8 (100%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	270..277		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	329..334		4/4 (100%)