DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphaq and gnaz

DIOPT Version :9

Sequence 1:	NP_725192.2	Gene:	Galphaq / 36384	FlyBaseID:	FBgn0004435	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_001072589.1	Gene:	gnaz / 780044	XenbaseID:	XB-GENE-980745	Length:	355	Species:	Xenopus tropicalis

Alignment Length:	408	Identity:	175/408 - (42%)
Similarity:	222/408 - (54%)	Gaps:	67/408 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MECCLSEEAKEQKRINQEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDED 65
            |.|..|.|.||..|.::.|::.||.:.:..|||:|||||||..|||||.:|||:|||..|::.|.
Frog     1 MGCRQSAEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEA 65

  Fly    66 KRGYIKLVFQNIFMAMQSMIKAMDMLKISYGQGEHSELADLVMSIDYETVTTF------------ 118
            .:.|..|:..|...::..:|:|:..|||.:...:.:          |:.|..|
Frog    66 CKEYKPLIIYNAIDSLTRIIRALATLKIEFHNPDRA----------YDAVQLFALTGPAESKGEI 120

  Fly   119 EDPYLNAIKTLWDDAGIQECYDRRREYQLTDSAKYYLKDLDRVAQPAYLPTEQDILRVRVPTTGI 183
            ....|..:|.||.|.|:|||:.|..||.|.|:|.|||.||:|:|...|:||.:||||.|..||||
Frog   121 TSELLGVMKRLWADPGVQECFSRSNEYHLEDNAAYYLNDLERIAAIEYIPTVEDILRSRDMTTGI 185

  Fly   184 IEYPFDLEEIRFSYLSDLARIEQADYLPTEQDILRARVPTTGILEYPFDLDGIVFRMVDVGGQRS 248
            :|..|..:|                                           :.|:|||||||||
Frog   186 VENKFTFKE-------------------------------------------LTFKMVDVGGQRS 207

  Fly   249 ERRKWIHCFENVTSIIFLVALSEYDQILFESDNENRMEESKALFRTIITYPWFQNSSVILFLNKK 313
            ||:|||||||.||:|||.|.||.||..|:|.:..:||.||..||.:|....||.|:|:|||||||
Frog   208 ERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKK 272

  Fly   314 DLLEEKIMYSHLVDYFPEYDGPQRDAITAREFILRMFVDLNPDSE-KIIYSHFTCATDTENIKLV 377
            |||.|||....|...||:|.| |.....|..:|.|.|.|||.:.| |.|||||||||||.||:.|
Frog   273 DLLAEKIRRIPLTVCFPDYKG-QNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFV 336

  Fly   378 FCAVKDTIMQNALKEFNL 395
            |.||.|.|:||.||...|
Frog   337 FDAVTDVIIQNNLKYIGL 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphaq	NP_725192.2	G-alpha	34..390	CDD:206639	159/368 (43%)
gnaz	NP_001072589.1	rne	<5..>32	CDD:236766	8/26 (31%)
gnaz	NP_001072589.1	G-alpha	34..349	CDD:206639	159/368 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R507
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.030