DRSC/TRiP Functional Genomics Resources

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Protein Alignment Galphaq and Galphao

DIOPT Version :10

Sequence 1:NP_725192.2 Gene:Galphaq / 36384 FlyBaseID:FBgn0004435 Length:396 Species:Drosophila melanogaster
Sequence 2:NP_523684.2 Gene:Galphao / 36104 FlyBaseID:FBgn0001122 Length:354 Species:Drosophila melanogaster


Alignment Length:393 Identity:176/393 - (44%)
Similarity:225/393 - (57%) Gaps:46/393 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MECCLSEEAKEQKRINQEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDED 65
            |.|..|.|.:.....::.||:.|:.|...|.:::||||||.|||||||.:|||:|||.||::.||
  Fly     1 MGCAQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAED 65

  Fly    66 KRGYIKLVFQNIFMAMQSMIKAMDMLKISYGQGEHSELADLVMSIDYETVTT--FEDPYLNAIKT 128
            .:.|..:|:.|...::.::::||..|.|.|...|....|.:|..:......|  |.:..|.|:|.
  Fly    66 FKQYRPVVYSNTIQSLVAILRAMPTLSIQYSNNERESDAKMVFDVCQRMHDTEPFSEELLAAMKR 130

  Fly   129 LWDDAGIQECYDRRREYQLTDSAKYYLKDLDRVAQPAYLPTEQDILRVRVPTTGIIEYPFDLEEI 193
            ||.|||:|||:.|..||||.|||||:|.||||:.                               
  Fly   131 LWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLG------------------------------- 164

  Fly   194 RFSYLSDLARIEQADYLPTEQDILRARVPTTGILEYPFDLDGIVFRMVDVGGQRSERRKWIHCFE 258
                        ..||.||||||||.||.||||:|..|....:.|::.|||||||||:|||||||
  Fly   165 ------------AKDYQPTEQDILRTRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFE 217

  Fly   259 NVTSIIFLVALSEYDQILFESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYS 323
            :||:|||.||:|||||:|.|.:..|||:||..||.:|....||.::|:|||||||||.||||..|
  Fly   218 DVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIRKS 282

  Fly   324 HLVDYFPEYDGPQRDAITAREFILRMFVDLNPDSEKIIYSHFTCATDTENIKLVFCAVKDTIMQN 388
            .|...||||.|.|... .|..:|...|...|..:.|.||.|.||||||.||:.||.||.|.|:.|
  Fly   283 PLTICFPEYTGGQEYG-EAAAYIQAQFEAKNKSTSKEIYCHMTCATDTNNIQFVFDAVTDVIIAN 346

  Fly   389 ALK 391
            .|:
  Fly   347 NLR 349

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GalphaqNP_725192.2 G-alpha 34..390 CDD:206639 166/357 (46%)
GalphaoNP_523684.2 G-alpha 34..348 CDD:206639 166/357 (46%)

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