Protein Alignment Galphaq and GNAL

DIOPT Version :9

• Sequence 1: NP_725192.2
• Gene: Galphaq / 36384
• FlyBaseID: FBgn0004435
• Length: 396
• Species: Drosophila melanogaster
• Sequence 2: NP_892023.1
• Gene: GNAL / 2774
• HGNCID: 4388
• Length: 458
• Species: Homo sapiens
• Alignment Length: 410
• Identity: 151/410 - (36%)
• Similarity: 229/410 - (55%)
• Gaps: 66/410 - (16%)

  Fly     7 EEAKEQKRINQEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGYIK 71
            |..||.:::::.|::.||..|||.::..:|||||.|||||||.:|||||:|.:|::.|:|:..|.
Human    93 EAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKIL 157

  Fly    72 LVFQNIFMAMQSMIKAMDML--KISYGQGEHSELADLVMSIDYETVTTFE--DPYLNAIKTLWDD 132
            .:.:|:..|:.:::.||..:  .:.....|:...:|.:.||  ..:|.||  ..:.:.:|.||||
Human   158 DIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSI--APITDFEYSQEFFDHVKKLWDD 220

  Fly   133 AGIQECYDRRREYQLTDSAKYYLKDLDRVAQPAYLPTEQDILRVRVPTTGIIEYPFDLEEIRFSY 197
            .|::.|::|..||||.|.|:|:|:.:|.|:
Human   221 EGVKACFERSNEYQLIDCAQYFLERIDSVS----------------------------------- 250

  Fly   198 LSDLARIEQADYLPTEQDILRARVPTTGILEYPFDLDGIVFRMVDVGGQRSERRKWIHCFENVTS 262
                    ..||.||:||:||.||.|:||.|..|.:|.:.|.|.||||||.||||||.||.:||:
Human   251 --------LVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTA 307

  Fly   263 IIFLVALSEYDQILFESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIM--YSHL 325
            ||::.|.|.|:.::.|.:|.||:.||..||.:|....|.:..|:||||||:|:|.||::  .|.:
Human   308 IIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKI 372

  Fly   326 VDYFPEY-----------DGPQRDAITAREFILR-MFVDLNP---DSEKIIYSHFTCATDTENIK 375
            .||||||           |..:...:|..:|.:| :|:.::.   |.:...|.|||||.|||||:
Human   373 EDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIR 437

  Fly   376 LVFCAVKDTIMQNALKEFNL 395
            .||...:|.|.:..||::.|
Human   438 RVFNDCRDIIQRMHLKQYEL 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphaq	NP_725192.2	G-alpha	34..390	CDD:206639	139/376 (37%)
GNAL	NP_892023.1	G_alpha	99..455	CDD:214595	147/400 (37%)
		G-alpha	120..452	CDD:206639	139/376 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810