Protein Alignment Galphaq and Gna14

DIOPT Version :10

• Sequence 1: NP_725192.2
• Gene: Galphaq / 36384
• FlyBaseID: FBgn0004435
• Length: 396
• Species: Drosophila melanogaster
• Sequence 2: NP_032163.3
• Gene: Gna14 / 14675
• MGIID: 95769
• Length: 355
• Species: Mus musculus
• Alignment Length: 393
• Identity: 262/393 - (66%)
• Similarity: 304/393 - (77%)
• Gaps: 43/393 - (10%)

  Fly     3 CCLSEEAKEQKRINQEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKR 67
            ||||.|.||.:||:.|||:||||||:|||||||||||||||||||||||||||||||||||||::
Mouse     5 CCLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRK 69

  Fly    68 GYIKLVFQNIFMAMQSMIKAMDMLKISYGQGEHSELADLVMSIDYETVTTFEDPYLNAIKTLWDD 132
            |:.|||:||||.|||:||:|||.|:|.|...::.|.|.::..::.:.||......:.|||.||.|
Mouse    70 GFTKLVYQNIFTAMQAMIRAMDTLRIQYMCEQNKENAQIIREVEVDKVTALSRDQVAAIKQLWLD 134

  Fly   133 AGIQECYDRRREYQLTDSAKYYLKDLDRVAQPAYLPTEQDILRVRVPTTGIIEYPFDLEEIRFSY 197
            .||||||||||||||:|||||||.|::|:|.|:::||:||:||||||||||||||||||
Mouse   135 PGIQECYDRRREYQLSDSAKYYLTDIERIAMPSFVPTQQDVLRVRVPTTGIIEYPFDLE------ 193

  Fly   198 LSDLARIEQADYLPTEQDILRARVPTTGILEYPFDLDGIVFRMVDVGGQRSERRKWIHCFENVTS 262
                                                 .|:|||||||||||||||||||||:|||
Mouse   194 -------------------------------------NIIFRMVDVGGQRSERRKWIHCFESVTS 221

  Fly   263 IIFLVALSEYDQILFESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVD 327
            ||||||||||||:|.|.||||||||||||||||||||||.|||||||||||||||||||||||:.
Mouse   222 IIFLVALSEYDQVLAECDNENRMEESKALFRTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLIS 286

  Fly   328 YFPEYDGPQRDAITAREFILRMFVDLNPDSEKIIYSHFTCATDTENIKLVFCAVKDTIMQNALKE 392
            |||||.||::|...||:|||:::.|.|||.||:||||||||||||||:.||.||||||:|..|:|
Mouse   287 YFPEYTGPKQDVKAARDFILKLYQDQNPDKEKVIYSHFTCATDTENIRFVFAAVKDTILQLNLRE 351

  Fly   393 FNL 395
            |||
Mouse   352 FNL 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphaq	NP_725192.2	G-alpha	34..390	CDD:206639	234/355 (66%)
Gna14	NP_032163.3	G-alpha	36..349	CDD:206639	234/355 (66%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	37..50		12/12 (100%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	174..182		6/7 (86%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	197..206		8/8 (100%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	266..273		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	325..330		4/4 (100%)