Protein Alignment Amph and RVS167

DIOPT Version :9

• Sequence 1: NP_523717.1
• Gene: Amph / 36383
• FlyBaseID: FBgn0027356
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_010676.1
• Gene: RVS167 / 851996
• SGDID: S000002796
• Length: 482
• Species: Saccharomyces cerevisiae
• Alignment Length: 630
• Identity: 121/630 - (19%)
• Similarity: 204/630 - (32%)
• Gaps: 189/630 - (30%)

  Fly     8 MLAKSVQKHAGRAKEKILQNLGKVDRTADEIFDDHLNNFNRQQASANRLQKEFNNYIRCVRAAQA 72
            |..|...|...||.:...|.....::|.|.:::|....|...:....:|.:|...|...|.....
Yeast     1 MSFKGFTKAVSRAPQSFRQKFKMGEQTEDPVYEDAERRFQELEQETKKLSEESKRYSTAVNGMLT 65

  Fly    73 ASKTLMDSVCEIYEPQWSG----------------------YDALQAQTGASESLWADFAHKLGD 115
            .......|:.||::| .||                      |.|:.|:  ..|:|..|.| .:.:
Yeast    66 HQIGFAKSMEEIFKP-ISGKMSDPNATIPEDNPQGIEASEQYRAIVAE--LQETLKPDLA-LVEE 126

  Fly   116 QVLIPLNTYTGQFPEMKKKVEKRNRKLIDYDGQRHSFQNLQANAN-KRKDDVKLTKGREQLEEAR 179
            :::.|..........::|...|||.|.:|.|...:::...:.... ..||:.:|.|.:.|:|.|:
Yeast   127 KIVTPCQELLKIITYIRKMATKRNHKKLDLDRHLNTYNKHEKKKEPTAKDEERLYKAQAQVEVAQ 191

  Fly   180 RTYEILNTELHDELPALYDSRILFLVTNLQTLFATE-QVFHNETAKIYSELEAIVDKLATESQRG 243
            :.|:..|..|..:||.|:.....|:.....:.:..: .:|:.    :|:.|:
Yeast   192 QEYDYYNDLLKTQLPILFSLEAEFVKPLFVSFYFMQLNIFYT----LYNRLQ------------- 239

  Fly   244 SNTLRKQTSNPIKTSSPVQSPVNKLNNANINSNYQNQITTNGGSSLANSPTSTSSSLQEPRFDSV 308
                            .::.|...||                 |.:..|..:...:::| :.|::
Yeast   240 ----------------DMKIPYFDLN-----------------SDIVESYIAKKGNVEE-QTDAL 270

  Fly   309 SSTP----------EPRPESPAAALVSATPSSPVENGVTTKSLERPELSGLNASAKATTTTQTSP 363
            :.|.          |........|....:|.|...:||           |..|.....|.|..:|
Yeast   271 TITHFKLGYSKAKLEMTRRKYGVATAEGSPVSGASSGV-----------GYGAGYDPATATSPTP 324

  Fly   364 T---EDKAVVSEAVKPSETEGAAVAASVTPAPPATPAQINGNNNEPSIVKEGGKQPKELPSTTSN 425
            |   ...|..|.|.:|:...|.|.|.. |.|...|.|               |.....:|.|...
Yeast   325 TGYGYGAAAPSYAAQPAAQYGTAAAVG-TAAAVGTAA---------------GAAAGAVPGTYPQ 373

  Fly   426 AEAAAEAAANNGNSIEEHKQKKLGNDTTVTATETVTVTQHSVTSTDTDNIVTISDTNTDTDTKTS 490
             .|||::....|...::..|::.|
Yeast   374 -YAAAQSPPLTGLGFQQSPQQQQG----------------------------------------- 396

  Fly   491 TGTSQKGRPVPVVNRHSVNNLNKNPFEDDDERIYEVPADANTADLPPGVLYRVKATYGYAKEDVD 555
                    |.|..:         ||....   :...||.|..|  .||| ..|.|.|.|..:...
Yeast   397 --------PPPAYS---------NPLTSP---VAGTPAAAVAA--APGV-ETVTALYDYQAQAAG 438

  Fly   556 ELSFEIGDLIRVIEYDDPEDQEEGWLMGQKEGTNEKGLFPANFTR 600
            :|||..|.:|.::: ..|:..|  |..|:..|  ::|:||.|:.:
Yeast   439 DLSFPAGAVIEIVQ-RTPDVNE--WWTGRYNG--QQGVFPGNYVQ 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Amph	NP_523717.1	BAR_Amphiphysin	26..238	CDD:153272	47/235 (20%)
		SH3_Amphiphysin	539..602	CDD:212724	19/62 (31%)
RVS167	NP_010676.1	BAR_Rvs167p	29..245	CDD:153283	45/252 (18%)
		SH3	425..478	CDD:418401	18/57 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343049
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3771
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	82	1.000	Inparanoid score	I1608
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46473
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R565
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820