Protein Alignment Amph and bin1b

DIOPT Version :10

• Sequence 1: NP_523717.1
• Gene: Amph / 36383
• FlyBaseID: FBgn0027356
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_001314899.2
• Gene: bin1b / 447863
• ZFINID: ZDB-GENE-030425-1
• Length: 576
• Species: Danio rerio
• Alignment Length: 657
• Identity: 178/657 - (27%)
• Similarity: 278/657 - (42%)
• Gaps: 145/657 - (22%)

  Fly     5 KGI---MLAKSVQKHAGRAKEKILQNLGKVDRTADEIFDDHLNNFNRQQASANRLQKEFNNYIRC 66
            ||:   .||.:|||...||:||::|.|||.|.|.|..|::.:.|||:|.....:|||:...|:..
Zfish     6 KGVNAGKLASNVQKRLTRAQEKVMQKLGKADETKDTAFEEQVANFNKQMNEGTKLQKDLKAYLLA 70

  Fly    67 VRAAQAASKTLMDSVCEIYEPQWSGYDALQA------------QTGASESLWADFAHKLGDQVLI 119
            |:.....||.|.|.:.|:|:|:|.|.:.:.:            ....::.||.||..||.|..:|
Zfish    71 VKTMHECSKRLHDCLAEMYDPEWFGKEEVDSIAEEMIEKEMDNNLEDTDLLWQDFHEKLLDNAVI 135

  Fly   120 PLNTYTGQFPEMKKKVEKRNRKLIDYDGQRHSFQNLQANANKRKDDVKLTK-------------- 170
            .::.|..|||::|.::.||.|||:|:|..||.|.::|  ..|:||:.|:.|
Zfish   136 SMDAYLAQFPDIKARIAKRERKLVDFDSARHHFASVQ--KGKKKDEAKIAKPLALVEKAAPVWAQ 198

  Fly   171 -------------GREQLEE----ARRTYEILNTELHDELPALYDSRILFLVTNLQTLFATEQVF 218
                         .|.|.||    |::.:|.:|.:|.:|||.|::||:...|...:::...|:.|
Zfish   199 GILTAHQIAQTNLTRNQAEEDLGRAQKVFEEINYDLQEELPTLWNSRVGLYVNTFRSVSGLEETF 263

  Fly   219 HNETAKIYSELEAIVDKLATESQRGSNTLRKQTSNPIKTSSPVQSPVNKLNNANINSNYQNQITT 283
            |.:..|:...|..|:.||  |.||       .....:.|:|..:|.    :.||     .||.|
Zfish   264 HRDMGKLNQNLSDIMTKL--EEQR-------VAKKGVTTASTGKSD----DAAN-----HNQET- 309

  Fly   284 NGGSSLANSPTSTSSSLQEPRFDSVSSTPEPRPESPAAALVSATPSSPVENGVTTKSLERPELSG 348
                  :::|.|.|...:.|        |..||..||:       |..|:........|..|:|.
Zfish   310 ------SDAPKSPSKPREVP--------PVSRPPRPAS-------SQEVKPDKIINLFEDAEVSD 353

  Fly   349 LNASAKATTTTQTSPTEDKAVVSEAVKPSETEGAAVAASVTPA--PPATPAQINGNNNEPSIVKE 411
            .|      ||||                  .|..|...|..||  |..:|:|...::||......
Zfish   354 SN------TTTQ------------------PEQGASWNSWEPAHSPAVSPSQRWDSDNEADAQPH 394

  Fly   412 GGKQPKELPSTTSNAEAAAEAAANNGNSIEEHKQKKLGND-TTVTATETVTVTQHSVTSTDTDNI 475
            |  ||...|....:...|.::........::....:.|.| .|....:.....:|  ...:...:
Zfish   395 G--QPYAAPEWDDDVTPAVQSYEPPSWDEQDGAPAQSGWDGQTAAPAQPDWEDEH--WDEEGSQV 455

  Fly   476 VTISDTNTDTDTKTSTGTSQKGRPVPVVNRHSVNNLNKNPFEDDDERIYEVPADAN---TADLPP 537
            ..:.||.|:.....:.....:..|      .....|..|          |.|...|   ..:|||
Zfish   456 GQVQDTETNWANDAAQDWEAESEP------PQWEELQSN----------EAPTVTNGSSDTELPP 504

  Fly   538 GVLYRVKATYGYAKEDVDELSFEIGDLIRVIEYDDPEDQEEGWLMGQKEG---TNE----KGLFP 595
            .||::||..:.|:..|.|||..:.||::.|:.:.:|::.::|||||.||.   .|:    ||:||
Zfish   505 SVLFKVKTMHDYSATDSDELDLKAGDIVLVLPFANPDEADDGWLMGVKESHWLQNKNLLAKGVFP 569

  Fly   596 ANFTRPI 602
            .|||:.:
Zfish   570 ENFTQKL 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Amph	NP_523717.1	BAR_Amphiphysin	26..238	CDD:153272	78/254 (31%)
		PTZ00449	<275..>396	CDD:185628	28/122 (23%)
		SH3_Amphiphysin	539..602	CDD:212724	28/69 (41%)
bin1b	NP_001314899.2	None