Protein Alignment Amph and amph

DIOPT Version :9

• Sequence 1: NP_523717.1
• Gene: Amph / 36383
• FlyBaseID: FBgn0027356
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: XP_021334960.1
• Gene: amph / 393804
• ZFINID: ZDB-GENE-040426-1711
• Length: 1308
• Species: Danio rerio
• Alignment Length: 653
• Identity: 182/653 - (27%)
• Similarity: 276/653 - (42%)
• Gaps: 131/653 - (20%)

  Fly     1 MTENKGIMLAKSVQKHAGRAKEKILQNLGKVDRTADEIFDDHLNNFNRQQASANRLQKEFNNYIR 65
            |.|.|..:.||:|||...||:||:||.|||.|.|.||.|:..:.||.||:...:|||:|...||.
Zfish     1 MAEIKTGIFAKNVQKRINRAQEKVLQKLGKADETKDEQFEQCVQNFKRQEFEGSRLQREMKAYIA 65

  Fly    66 CVRAAQAASKTLMDSVCEIYEPQWSGYDALQAQTGASESLWADFAHKLGDQVLIPLNTYTGQFPE 130
            .|:..|.||..|.:|:.|:|||.|.|.|.:.......::||.||..||.|..:..|.||..|||:
Zfish    66 AVKGMQQASMNLTESLHEVYEPDWHGKDDVMTIGKNCDALWEDFHQKLVDSTINTLETYLTQFPD 130

  Fly   131 MKKKVEKRNRKLIDYDGQRHSFQNLQANANKRKDDVKLTKGREQLEEARRTYEILNTELHDELPA 195
            :|.:|.||:|||||||..||..:.||.:.  .:::.::.|..|.|::|:|.::.||..|.||||.
Zfish   131 LKVRVAKRSRKLIDYDSARHHLETLQTST--MRNEKRIAKAEEDLKKAQRVFDDLNVGLQDELPT 193

  Fly   196 LYDSRILFLVTNLQTLFATEQVFHNETAKIYSELEAIVDKLATESQRGSNTLR-----KQTSNPI 255
            |:|||:.|.|:..:.:.:.|..||.|.:.:..:|..:::|||.:......|::     |:.|.|:
Zfish   194 LWDSRVGFYVSTFKNVSSLEARFHREISFLCHKLYEVMNKLAEQHSDKMFTIQGAPREKRDSGPL 258

  Fly   256 ---KTSSPV--QSPVNKLNNANINSNYQNQITTNGGSSLANSPTSTSSSLQEPRFDSVSSTPEPR 315
               :|.||.  :||                     .||.|.||..|...         :|...||
Zfish   259 RLARTPSPPDDESP---------------------DSSPAASPNHTLRP---------TSPGPPR 293

  Fly   316 PESPAAALVSATPSSPVENGVTTKSLER-----------PELSGLNASA---------------- 353
            |:|| :.|....|..|......|:.|::           ||:|..:...
Zfish   294 PKSP-SQLKMGPPKPPPPKVTPTRELQQEQIIDLFDGGFPEISVTSPQPNERPGESLLDLDFDPF 357

  Fly   354 KATTTTQTSPTEDKAVVSEAVKPSETEGAAVAASVTPAPPATPAQINGNNNEPSIVKEGGKQPKE 418
            |..|:|....|:  :.||:.:......|.|    ..||.|||.|....|     ...:.|.....
Zfish   358 KPDTSTPIGQTQ--SPVSQTLPWDLWTGDA----AQPAQPATDAGFTAN-----WAADFGSSATT 411

  Fly   419 LPSTTSNAEAAAEAAA---NNGNSIEEHKQKKLGNDTTVTATETVTVTQHSVTSTDTDNIVTISD 480
            :...::|.:.||:...   .:|...:...|.: |.    |||:       .|.:.||:|   ..:
Zfish   412 VTDESANTQPAADGQGWPPADGWPTDSTPQPQ-GE----TATD-------EVRAWDTEN---YPE 461

  Fly   481 TNTDTDTKTSTGTSQKGRPVPVVNRHSV----NNLNKNPFEDDDER---IYEVPADANTADLP-- 536
            .|.|.| ..:.|..:..:..|...:..|    .:...|..|..:|:   :.|......|..|.
Zfish   462 PNPDCD-PCAVGGGEAEQQHPGQGQEGVEEGQTDWATNQVEWAEEKTGFVSEEGGAEETVGLQAM 525

  Fly   537 PGVLYRVKATYGYAKEDVDELSFEIGDLIR------------------VIEYDDPEDQEEGWLMG 583
            ||:::    |..:.:|..|.:.....|..|                  ..|:.|...|..||:..
Zfish   526 PGIIF----TNEFGQEIQDPMEGAGADSSRWGLSSQVDLDGSGSEYETAEEWGDVPGQNGGWVSA 586

  Fly   584 QKE 586
            ..|
Zfish   587 DDE 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Amph	NP_523717.1	BAR_Amphiphysin	26..238	CDD:153272	85/211 (40%)
		SH3_Amphiphysin	539..602	CDD:212724	11/66 (17%)
amph	XP_021334960.1	BAR_Amphiphysin_I_II	26..236	CDD:153295	85/211 (40%)
		Atrophin-1	<248..483	CDD:331285	62/292 (21%)
		FtsK	<985..>1149	CDD:332908
		SH3	1237..1307	CDD:327375

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577739
Domainoid	1	1.000	177	1.000	Domainoid score	I3543
eggNOG	1	0.900	-	-		E1_KOG3771
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	200	1.000	Inparanoid score	I3747
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1366218at2759
OrthoFinder	1	1.000	-	-		FOG0001177
OrthoInspector	1	1.000	-	-		otm24508
orthoMCL	1	0.900	-	-		OOG6_105748
Panther	1	1.100	-	-	O	PTHR46514
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R565
SonicParanoid	1	1.000	-	-		X1098
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.790