DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Amph and Bin3

DIOPT Version :9

Sequence 1:	NP_523717.1	Gene:	Amph / 36383	FlyBaseID:	FBgn0027356	Length:	602	Species:	Drosophila melanogaster
Sequence 2:	NP_001013204.1	Gene:	Bin3 / 361065	RGDID:	1308253	Length:	253	Species:	Rattus norvegicus

Alignment Length:	256	Identity:	59/256 - (23%)
Similarity:	109/256 - (42%)	Gaps:	37/256 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 GRAKEKILQNLGKVDRTADEIFDDHLNNFNRQQASANRLQKEFNNYIRCVRAAQAASKT------ 76
            |:.|::|      |.:|.:..|:.......:.:....||||:..   :...|..|.||:
  Rat     9 GQPKKQI------VSKTVERDFEREYGKLQQLEEQTKRLQKDMK---KSTDADLAMSKSAVKISL 64

  Fly    77 --LMDSVCEIYEPQWSGYDALQAQTGASESLWADFAHKLGDQVLIPLNTYTGQFPEMKKKVEKRN 139
              |.:.:||..:.......||.......::...:..:::...|:.||..:...||.:...|::|.
  Rat    65 DLLSNPLCEQDQDFLRMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSIFPSLNMAVKRRE 129

  Fly   140 RKLIDYDGQRHSFQNLQANANKRKDD-------VKLTKGREQLEEARRTYEILNTELHDELPALY 197
            :.|.||.       .|||...|.::.       .||.:.||:|...|..:|..|.:|.||:|..|
  Rat   130 QALQDYG-------RLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNKQLLDEMPRFY 187

  Fly   198 DSRILFLVTNLQTLFATEQVFHNETAKIYSELEAIVDKLATESQRGSNTLRKQTSNPIKTS 258
            :||:.:...:.::|...:.::::|..||:.:|...:|      |.|.:...::..|..|.|
  Rat   188 NSRLDYFQPSFESLIRAQVIYYSEMHKIFGDLTQQLD------QPGHSDEHRERENETKLS 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Amph	NP_523717.1	BAR_Amphiphysin	26..238	CDD:153272	51/226 (23%)
Amph	NP_523717.1	SH3_Amphiphysin	539..602	CDD:212724
Bin3	NP_001013204.1	BAR_Bin3	12..236	CDD:153274	55/245 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3771
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810