Protein Alignment Sin3A and SNL5

DIOPT Version :10

• Sequence 1: NP_001246282.1
• Gene: Sin3A / 36382
• FlyBaseID: FBgn0022764
• Length: 2066
• Species: Drosophila melanogaster
• Sequence 2: NP_001185268.1
• Gene: SNL5 / 842283
• AraportID: AT1G59890
• Length: 1167
• Species: Arabidopsis thaliana
• Alignment Length: 1681
• Identity: 347/1681 - (20%)
• Similarity: 536/1681 - (31%)
• Gaps: 724/1681 - (43%)

  Fly   229 QPVQQSPL----GKAQTPPSSVVANSIPVGGTTPPQGQSGNATPRLKVEDALSYLDQVKYQYADQ 289
            :|..:.|.    |:....||::..     ||||      |..|    ..|||:||..||..:.|.
plant    11 EPQMRGPTVSSRGETNGRPSTISG-----GGTT------GGLT----TVDALTYLKAVKDMFQDN 60

  Fly   290 PQIYNNFLDIMKEFKSHCIDTPGVIERVSTLFKGHTELIYGFNMFLPPGYKIEIHSDALGCSVPV 354
            .:.|..||.:||:||:..:||.|||.||..||||:.:|:.|||.|||.||||.:.
plant    61 KEKYETFLGVMKDFKAQRVDTNGVIARVKDLFKGYDDLLLGFNTFLPKGYKITLQ---------- 115

  Fly   355 VSMPSPPGAPTSTGTVHMLTGNSSMSGAGHIAIKTTNAATLTPAAGAGAAAAAAAVAQIQSAGAV 419
                                                                             
plant   116 ----------------------------------------------------------------- 115

  Fly   420 NLMTHGGASLTQTTIHALQQATPPQSQSPGGGHVHVSVTNSTAANAVVPGQPGISVSAHNVPQNY 484
                                   |:.:.|
plant   116 -----------------------PEDEKP------------------------------------ 121

  Fly   485 SRDRERATITPTGQVAGAAANVNASASIVVGGPPTPNSLSELSPHGGAGGGPGAGAAQHNLHHIQ 549
                                                                             
plant   122 ----------------------------------------------------------------- 121

  Fly   550 QAHQSILLGETGQQNQPVEFNHAITYVNKIKNRFQNQPAKYKKFLEILHDYQREQKVMKEGSLNQ 614
                          .:||:|..||.:||:||.||......|||||:||:.|::|.|     |:|
plant   122 --------------KKPVDFQVAIEFVNRIKARFGGDDRAYKKFLDILNMYRKETK-----SIN- 166

  Fly   615 GKMLTEQEVYTQVAKLFGQDEDLLREFGQFLPDATNHQSGQYMSKSASVHNDHGKRPTATLSGGA 679
                   |||.:|..||...||||.||..||||
plant   167 -------EVYQEVTLLFQDHEDLLGEFVHFLPD-------------------------------- 192

  Fly   680 HITMSSASPAPSGSPLHLGATTLPQIDKSAHAAAIGNLSAVNTSVSIKTYNNNQQQQNHVIGSGL 744
                                                    ...|||:
plant   193 ----------------------------------------FRGSVSV------------------ 199

  Fly   745 NATRNDILFEKDYHAGLQQQAHQRGAGVGGHHHLAGTAAGANIGRPGVGASVMVSYDKEHRNNHH 809
                ||.||:::                             .|.|              .||:
plant   200 ----NDPLFQRN-----------------------------TIPR--------------DRNS-- 215

  Fly   810 VQKYVGHAPNQNLTHGHNAKKSPSYGIPSVIGSMPHISDNSLDRSSPGISYATPPLPSGPHGQHN 874
              .:.|..|.      |..||                    :.||.              |.::.
plant   216 --TFPGMHPK------HFEKK--------------------IKRSR--------------HDEYT 238

  Fly   875 SGSATRRPGDDSLVGHYASGAPPAKRPKPYCRDVSFSEASSKCTISDAAFFDKVRKALRSPEVYD 939
            ..|..|..||::||. |::|....|
plant   239 ELSDQREDGDENLVA-YSAGNSLGK---------------------------------------- 262

  Fly   940 NFLRCLTLFNQEIVSKTELLGLVSPFLMKFPDLLRWFTDFLGPPSGQPAGGLIDGMPLAATQRQG 1004
                  :|.||                              |...|.|.....:|:.:.
plant   263 ------SLANQ------------------------------GQWPGYPKVEDTEGIQIY------ 285

  Fly  1005 GGSSNSSHDR-----------GTSHQSAAEYVQDVDLSSCKRLGASYCALPQSTVPKKCSGRTAL 1058
              .||..|:|           .|:|.:.|  :.::||:.|.:...||..||.....:..|.|.:|
plant   286 --ESNGGHERDPDIGSQKNLLSTNHMAKA--INELDLTDCAQCTPSYRRLPDDYPIQIPSYRNSL 346

  Fly  1059 CREVLNDKWVSFPTWASEDSTFVTSRKTQFEETIYRNIHRTEDERFELDLVIEVNSATIRVLENL 1123
            ..:||||.|||. |..|||.:|...||.|:||:::    |.||:|||||:::|..||.|:.:|:|
plant   347 GEKVLNDHWVSV-TSGSEDYSFKHMRKNQYEESLF----RCEDDRFELDMLLESVSAAIKRVESL 406

  Fly  1124 QKKMSRMSTEELSKFHLDDHLGGTSQTIHQRAIHRIYGDKSGEIITGMKKNPFVAVPIVLKRLKV 1188
            .:|::..:....:...:.:||    ..::.|.|.|:|||...:::..:|||..:|:|::|.|||.
plant   407 LEKINNNTISIETPICIREHL----SELNLRCIERLYGDYGLDVMDFLKKNSHIALPVILTRLKQ 467

  Fly  1189 KEEEWREAQKTFNKQWREQNEKYYLKSLDHQAINFKPNDMKALRSKSLFNEIETLYDERHDQED- 1252
            |:|||...:..|.|.|.|...|.:.|||||::..||..|.|.|.:|.|..||:.:.:.:| :||
plant   468 KQEEWARCRADFRKVWAEVYAKNHHKSLDHRSFYFKQQDSKNLSTKGLVAEIKDISERKH-KEDL 531

  Fly  1253 ------DAMEPFGPHLVLPYKDKTILDDAANLLIHHVKRQTGIQKQEKQKIKQIIRQFVPDLFFA 1311
                  .....|.|.:...|.|..:..|...|:.::.:.....::.:  |:.::...|:..:|..
plant   532 LRAIAVGTKPSFTPDVEFIYTDTKVHTDLYKLIKYYCEEICATEQSD--KVMKLWVTFLEPMFGV 594

  Fly  1312 PRQ-----------PLSDDERDDAFPFLVDDNT---------------KMD-------------V 1337
            |.:           .:.|::........|.:||               ||.             .
plant   595 PSRSETIETMKDVAKIEDNQEHHDASEAVKENTCDGSMASNLKPLTPPKMPNKENPMIQGSSFAQ 659

  Fly  1338 DSPLGRTES----------STRNAKSTPSESASP--------ARSNASTSSVTPAGIKKETDDSK 1384
            |.|:...||          :..|..|.||:..|.        ..:.:..|.|:..|.|.|.::
plant   660 DLPVNTGESIQQDKLHDVAAITNEDSQPSKLVSTRNDLIMEGVENRSRVSDVSMGGHKVEREE-- 722

  Fly  1385 ATTGSFAPASS-----------------------------------------ATASSATPVDDAT 1408
               |..:|..|                                         .|.|:|.|.||..
plant   723 ---GELSPTESCEQENFEVYKENGLEPVQKLPDNEISNTDREPKEGACGTEAVTRSNALPEDDDN 784

  Fly  1409 PSTSSAAAAASAASSSTVSGTE--GKPKDDPLSSHKEEGAGSTSSGVATSPRQAQDTAGAGVDVE 1471
            ..|...:.....||...||.::  |:...|  ..||...:.:.:.|:..| .:.:|  |:.....
plant   785 KITQKLSEGDENASKFIVSASKFGGQVSSD--EEHKGAESENEAGGMVNS-NEGED--GSFFTFS 844

  Fly  1472 IKLEHPADFSNPKLLPPHAHG--------QREDESYTLFFANNNWYLFLRLHAILCDRLHVMYER 1528
            .:...|.     |.|..|..|        .|.|.  .:|:.|::.|:..|||.:|       |||
plant   845 ERYLQPV-----KPLAKHVPGTLQASECDTRNDS--RVFYGNDSLYVLFRLHQML-------YER 895

  Fly  1529 ARLLAIEEERCRVNRRESTATALRLKPKPEIQVEDYYPTFLDMLKNVLDGNMDSNTFEDTMREMF 1593
            .:...|..|| :....:||:|             |.|..|::.|.|:|||:.|:..|||..|.:.
plant   896 IQSAKIHSER-KWKAPDSTST-------------DSYTRFMEALYNLLDGSSDNTKFEDECRAII 946

  Fly  1594 GIYAYISFTLDKVVSNAVRQLQYCVTERAALDCVELFATEQRRGCTGGFCRDAHKTFDREMSYQR 1658
            |..:|:.|||||:|...|:.|.....:......::|:|.|..|. .|.|       ||  :.|..
plant   947 GAQSYVLFTLDKLVQKFVKHLHAVAADETDTKLLQLYAYENYRK-PGRF-------FD--IVYHE 1001

  Fly  1659 KAESILNEENCFKVYIYKIDCRVTIELLDSEPEEVDKPAALKAQKFSKYVER--------LANPA 1715
            .|.::|:::|.:::.......|:.|:|::|..::.:..|......|:.|::.        ...|.
plant  1002 NARALLHDQNIYRIEYSSAQTRLGIQLMNSWNDQPEVTAVTVEPGFANYLQNDFLSFVSDEEKPG 1066

  Fly  1716 LGGGGN----TGRSDSALGNDSVVDG-------------SDIKTEADEDTAELRYR 1754
            |....|    :|..:.:||....::|             |..|.:.:..||:|.||
plant  1067 LFLKRNKAKLSGPGEESLGMSRALEGLNIINEVECKIACSSFKVKYEPHTADLLYR 1122

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sin3A	NP_001246282.1	Sin3	238..1719	CDD:227889	332/1614 (21%)
SNL5	NP_001185268.1	Sin3	45..1118	CDD:227889	332/1626 (20%)