Sequence 1: | NP_610798.1 | Gene: | ClC-b / 36381 | FlyBaseID: | FBgn0033755 | Length: | 813 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_000074.3 | Gene: | CLCN1 / 1180 | HGNCID: | 2019 | Length: | 988 | Species: | Homo sapiens |
Alignment Length: | 714 | Identity: | 178/714 - (24%) |
---|---|---|---|
Similarity: | 316/714 - (44%) | Gaps: | 132/714 - (18%) |
- Green bases have known domain annotations that are detailed below.
Fly 89 PNRNINSSEPIFH-------------LRSRTAAASTPNYESLD-YEVCENTLFQDEQ--RKRLTE 137
Fly 138 RFSLRKDIIRWIIFIQIGIITALIACTIDIIIEELSIRKYTFLYNSVKENVPLSDASDRDLLIPY 202
Fly 203 LYWLLFSIVPVAFGAAMVTYIEPITAGSGIPQVKSYLNGVKIPRIVRIKTLAVKAIGVITSVVGG 267
Fly 268 LAGGKEGPMIHAGAVVAAGISQGKSTTFLKDFRIFKAFRDDHEKRDFVLGGGAAGVSAAFGAPIG 332
Fly 333 GMLFSLEEAASFWNQNLIWRTLVASIISVFTLNIVLSAYHGLNDFTFTGLFNLG-KFDTPLKFDY 396
Fly 397 FELPIFMILGVTGGLLGAAWNSLNTKI------NKFRKRFI-------PWKIGKVLEAVVVA--- 445
Fly 446 ---MMGVTLACLMIYFINDCRPLGNDPTNNPVQLFCEDNEYNAVAALWFQTPEATVRSLFHDPPG 507
Fly 508 SHKILTLALFTVVYYVLSCATFGLNVSLGVFIPTALVGAAWGRLLAMLTYYVFPQA----EFLH- 567
Fly 568 --PGKYALIGAAANLGGVLRMTISLSVILMETTGVETSFFFPLIIALISAKWVGDYFNEGIYDTQ 630
Fly 631 IQVN---HVPMLTWEPLPQYKGLKAREILSKPVICIKIRDSANYIY----EMLKKCDHNGFPVVD 688
Fly 689 DVCGDRRSEGRVCGIILRSQLIVILLKSLYVENKRFWLPETSIQTFRDLYPRFPSIKSVRKLDE 752 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
ClC-b | NP_610798.1 | CBS_pair_EriC_assoc_euk_bac | 674..811 | CDD:239964 | 16/79 (20%) |
ClC_6_like | 115..639 | CDD:239657 | 146/556 (26%) | ||
Voltage_CLC | 213..620 | CDD:279048 | 119/433 (27%) | ||
CBS | 653..811 | CDD:223591 | 22/104 (21%) | ||
CLCN1 | NP_000074.3 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 65..92 | 3/26 (12%) | |
ClC_1_like | 131..592 | CDD:239655 | 134/506 (26%) | ||
Selectivity filter part_1. /evidence=ECO:0000250 | 188..192 | 3/3 (100%) | |||
Selectivity filter part_2. /evidence=ECO:0000250 | 230..234 | 3/3 (100%) | |||
Selectivity filter part_3. /evidence=ECO:0000250 | 482..486 | 2/3 (67%) | |||
CBS_pair_SF | 605..869 | CDD:417695 | 22/105 (21%) | ||
CBS repeat | 610..820 | CDD:341358 | 21/100 (21%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 713..764 | ||||
CBS repeat | 826..868 | CDD:341358 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 880..988 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG0038 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |