Protein Alignment Cyp301a1 and cyp27a1.2

DIOPT Version :10

• Sequence 1: NP_610796.1
• Gene: Cyp301a1 / 36378
• FlyBaseID: FBgn0033753
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_073769098.1
• Gene: cyp27a1.2 / 795106
• ZFINID: ZDB-GENE-081104-511
• Length: 580
• Species: Danio rerio
• Alignment Length: 535
• Identity: 143/535 - (26%)
• Similarity: 233/535 - (43%)
• Gaps: 100/535 - (18%)

  Fly    24 PRISGAGSRRAQCRESSTGVATCP-HLADSEEASAPRI---------------HSTSEWQNALPY 72
            |..:..|.|.|....::..|:... |.....||..|.|               :|..|.|  |..
Zfish    87 PTAAATGFRSAAGNAAAASVSVQDGHRKLKTEADLPEIKIFTMLYQMLFKGYLNSVHELQ--LYQ 149

  Fly    73 NQIPGPKPIPILGNTWRLMPIIGQYTISDVAKISSLLHDRYGRIVRFGGLIGRPDLLFIYDADEI 137
            .|:.||        .|:                           :..|.|.|    :.|...:.:
Zfish   150 KQVYGP--------LWK---------------------------INAGNLQG----ISISSVELL 175

  Fly   138 EKCYRSEGPTPFRPSMPSLVKYKSVVRKDFFGDLGGVVGVHGEPWREFRSRVQKPVLQLSTIRRY 202
            |:..|.:...|.|..|....::     :|..|...|.....||.|.:.|:.:.|.:|......:|
Zfish   176 EELLRKDEKYPCRGYMTLWTEH-----RDLRGISYGPFTEEGEKWYKLRAVLNKRMLHPKDSVQY 235

  Fly   203 LQPLEVITEDFLVRCENL--LDENQELPEDFDNEIHKWSLECIGRVALDTRLGCLESNLKPDSEP 265
            ...:..:..||:.|...|  :....:|..:..||::::|||.|..:..:||:||||..:  .:|.
Zfish   236 GDVVNAVITDFIKRIYYLREMSPTGDLVSNLTNELYRFSLEGIASILFETRIGCLEKEI--PAET 298

  Fly   266 QQIID----AAKYALRNVATLELKAPYW--RYFPTPLWTRYVKNMN--FFVG---VCMKYIQSAT 319
            |:.|:    ...|:: :||.|    |.|  :||  |.|.:|:...:  |..|   :.|| :::..
Zfish   299 QKFINFIAQMFTYSM-HVALL----PNWTRKYF--PFWQKYIDGWDGIFKFGTKMIDMK-MEAIQ 355

  Fly   320 ERLKT-QDPSLRAGE--PSLVEKVILSQKDEKIATIMALDLILVGIDTISMAVCSMLYQLATRPV 381
            :|:.| ||.   |||  ..|:....:|:||   ......:|:|.|:|:.|..:...||.|:..|.
Zfish   356 KRVDTNQDV---AGEYLTYLLSNGKISRKD---VYGSVSELLLAGVDSTSNTMLWALYLLSKDPE 414

  Fly   382 DQQKVHEELKRLLPDPNTPLTIPLLDQMHHLKGFIKEVFRMYSTVIGNGRTLMEDSVICG-YQVP 445
            .|:.:::|:.::|.|...| |...::.|..||..|||..|:|..|..|.|.:.|..|:.| |..|
Zfish   415 AQETLYQEVTKVLKDDRIP-TAEEVNSMPFLKAVIKETLRLYPVVPVNSRLIAETEVVIGEYFFP 478

  Fly   446 KGVQAVFPTIVTGNMEEYVTDAATFRPERWLKPQHGGTPGKLHPFASLPYGYGARMCLGRRFADL 510
            |.........|....|:...:...|:|||||:  .|.|  :.:||.|:|:|:|.|.|:|||.|:|
Zfish   479 KKTTFTLCHYVISRDEKVFPEPQKFKPERWLR--DGRT--RPNPFGSIPFGFGVRACVGRRIAEL 539

  Fly   511 EMQILLAKLLRNYKL 525
            ||.:.||:|::.:::
Zfish   540 EMHLALARLIKLFEM 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp301a1	NP_610796.1	CYP24A1-like	110..547	CDD:410677	125/433 (29%)
cyp27a1.2	XP_073769098.1	None