Protein Alignment Cyp301a1 and CYP26B1

DIOPT Version :9

• Sequence 1: NP_610796.1
• Gene: Cyp301a1 / 36378
• FlyBaseID: FBgn0033753
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_063938.1
• Gene: CYP26B1 / 56603
• HGNCID: 20581
• Length: 512
• Species: Homo sapiens
• Alignment Length: 524
• Identity: 116/524 - (22%)
• Similarity: 211/524 - (40%)
• Gaps: 92/524 - (17%)

  Fly    49 LADSEEASAPRIHSTSEWQNALPYNQIP-GPKPIPILGNT--WRLMPIIGQYTISDVAKISSLLH 110
            ||.|::....|..:|.:....||   || |....|::|.|  |.|..          :...|...
Human    26 LAVSQQLWQLRWAATRDKSCKLP---IPKGSMGFPLIGETGHWLLQG----------SGFQSSRR 77

  Fly   111 DRYGRIVRFGGLIGRPDLLFIYDADEIEKCYRSEG---PTPFRPSMPSLVKYKSVVRKDFFGDLG 172
            ::||.:.: ..|:||| |:.:..|:.:.|....|.   .|.:..|...|:...:|  .:..||
Human    78 EKYGNVFK-THLLGRP-LIRVTGAENVRKILMGEHHLVSTEWPRSTRMLLGPNTV--SNSIGD-- 136

  Fly   173 GVVGVHGEPWREFRSRVQKPVLQLSTIRRYLQPLEVITEDFL------VRCENLLDENQELPEDF 231
                :|..     :.:|...:.....:..||..::::.:|.|      ....|:..|.|:|
Human   137 ----IHRN-----KRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPEAINVYQEAQKL---- 188

  Fly   232 DNEIHKWSLECIGRVALDTRLGCLESNLKPDSEPQQIIDAAKYALRNVATLELKAPYWRYFPTPL 296
                       ..|:|:...||.    ..|:.:...:.:..:..:.||.:|.:..|:..|
Human   189 -----------TFRMAIRVLLGF----SIPEEDLGHLFEVYQQFVDNVFSLPVDLPFSGY----- 233

  Fly   297 WTRYVKNMNFFVGVCMKYIQSATERLKTQDPSLRAGEPSL--VEKVILSQKDE-KIATIM----- 353
             .|.::        ..:.:|...|:...:......|:..|  ::.:|.|.|:. |..|:.
Human   234 -RRGIQ--------ARQILQKGLEKAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDG 289

  Fly   354 ALDLILVGIDTISMAVCSMLYQLATRPVDQQKVHEELKR--LLPDPNTP----LTIPLLDQMHHL 412
            .|:||.....|.:.|..|::.||...|...:|:.:||:.  :|.....|    |.:..|..:.:|
Human   290 TLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYL 354

  Fly   413 KGFIKEVFRMYSTVIGNGRTLMEDSVICGYQVPKGVQAVFPTIVTGNMEEYVTDAATFRPERWLK 477
            ...||||.|:::.:.|..||:::...:.|:|:|||...::....|.:......|...|.|:|:.:
Human   355 DCVIKEVMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQ 419

  Fly   478 PQHGGTPGKLHPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKLEYNHK--PLDYAVTFMY 540
            .:.....|:.|   .||:|.|.|.|||:..|.|.:::|..:|....:.|...:  |....|..::
Human   420 ARSEDKDGRFH---YLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRITLVPVLH 481

  Fly   541 APDG 544
            ..||
Human   482 PVDG 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp301a1	NP_610796.1	p450	76..530	CDD:299894	104/479 (22%)
CYP26B1	NP_063938.1	p450	23..490	CDD:325183	116/524 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D871849at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010