Protein Alignment Cyp301a1 and cyp27a3

DIOPT Version :10

• Sequence 1: NP_610796.1
• Gene: Cyp301a1 / 36378
• FlyBaseID: FBgn0033753
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001116749.1
• Gene: cyp27a3 / 565876
• ZFINID: ZDB-GENE-081105-124
• Length: 513
• Species: Danio rerio
• Alignment Length: 442
• Identity: 126/442 - (28%)
• Similarity: 207/442 - (46%)
• Gaps: 66/442 - (14%)

  Fly   108 LLHDRYGRIVRFGGLIGRPDLLFIYDADEIEKCYRSEGPTPFRPSMPSLVKYKSVVRKDFFGDLG 172
            |...:||.:|          ::.:..||.||:..|.||..|.|..||....|:. :|...:|.|.
Zfish    84 LWKSKYGPLV----------IVNVASADLIEQVLRQEGRHPIRTDMPHWRGYRK-LRNHAYGPLT 137

  Fly   173 GVVGVHGEPWREFRSRVQKPVLQLSTIRRYLQPLEVITEDFLVRCENL--LDENQELPEDFDNEI 235
            .:    |..|:..||.:...:|:...:..|...:..:..||:.:...|  ...|..:..|...|:
Zfish   138 EM----GPEWQRIRSILNPRMLKPKHVSNYTNAINGVVSDFIEKMAKLKTTKGNDVMVYDVAGEL 198

  Fly   236 HKWSLECIGRVALDTRLGCLESNLKPDSEPQQIIDAAK-YALRNVATLELK-----APYWRYFPT 294
            :|::.|.|..|..:||:|||...: |:...:.|....: :.|..:..|..|     .|:|::| .
Zfish   199 YKFAFEGISSVLFETRMGCLNDEI-PEETQKFIFSVGEMFRLSPIVILFPKFLWPYMPFWKHF-V 261

  Fly   295 PLWTRYVKNMNFFVGVCMKYIQSATERLKTQDPSLRAGEPSLVEKVILSQK---DEKIATIMALD 356
            .:|....|..:..|...|..||   |::||..|.    |...:..:::|::   .|.:.:|  .:
Zfish   262 AVWDHLFKVADELVQQKMTEIQ---EKVKTGSPV----EGEYLTHLLISEQMSFTEVLGSI--TE 317

  Fly   357 LILVGIDTISMAVCSMLYQLATRPVDQQKVHEELKRLLPDPNTPLTIPLLDQMHHLKGFIKEVFR 421
            |:|.|:||.|..:...||.||..|..|||:|||:..:.|...||.:.. :.:|..||..::|..|
Zfish   318 LLLAGVDTTSNTISWALYHLAREPEIQQKLHEEVVSVCPGDKTPSSDD-ITRMPLLKAIVRETLR 381

  Fly   422 MYSTVIGNGRTLMEDSVICG-YQVPKGV------------QAVFPTIVTGNMEEYVTDAATFRPE 473
            :|..|.||.|.:.|:.::.| :..||..            :.|||            |...|.|:
Zfish   382 LYPVVPGNARVVAENEIVVGDHLFPKNTLFHLCHFAVSYDETVFP------------DPFAFLPQ 434

  Fly   474 RWLKPQHGGTPGKLHPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKL 525
            ||::.|...:.   |||.|:|:|:|.|.|||||.|:|||.:||::|::.|::
Zfish   435 RWIREQKQLSQ---HPFGSVPFGFGIRACLGRRVAELEMYLLLSRLIKRYEV 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp301a1	NP_610796.1	CYP24A1-like	110..547	CDD:410677	125/440 (28%)
cyp27a3	NP_001116749.1	CYP27A1	78..508	CDD:410739	126/442 (29%)