Protein Alignment Cyp301a1 and Cyp4d14

DIOPT Version :10

• Sequence 1: NP_610796.1
• Gene: Cyp301a1 / 36378
• FlyBaseID: FBgn0033753
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 498
• Identity: 119/498 - (23%)
• Similarity: 215/498 - (43%)
• Gaps: 97/498 - (19%)

  Fly    75 IPGPKPIPILGNTWRLMPIIGQYTISDVAKISSLLHDRYGRIV-RFG-----GLIGRPDLLFIYD 133
            |.|||..|::||.    |::    |::..|..|.:.|...|:: .||     .::|....: ..|
  Fly    33 IRGPKSYPLVGNA----PLL----INESPKSKSSIFDMQFRLIAEFGKNIKTQMLGESGFM-TAD 88

  Fly   134 ADEIEKCYRSEGPTPFRPSMPSLVKYKSVVRKDFFGDLGGVVGVHGEPWREFRSR-VQKPVLQLS 197
            :..||....|: .|..:.::.||:       .::.||  |::...|:.|  ||.| :..|.....
  Fly    89 SKMIEAIMSSQ-QTIQKNNLYSLL-------VNWLGD--GLLISQGKKW--FRRRKIITPAFHFK 141

  Fly   198 TIRRYLQPLEVITEDFLVRCENLLDENQELPEDFDNEIHKWSLECIGRVALD----TRLGC-LES 257
            .:..:   :||..:......:.|.|.     .|....|:.:.:.|:  .|:|    |.:|. :.:
  Fly   142 ILEDF---VEVFDQQSATMVQKLYDR-----ADGKTVINMFPVACL--CAMDIIAETAMGVKINA 196

  Fly   258 NLKPDSEPQQIIDAAKYAL---------RNVATLELKAPYWRYFPTPL--WTRYVKNMNFFVGVC 311
            .|:|.....|.:..|...|         |...|::|      ::|..|  ....||||:.|....
  Fly   197 QLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKL------FYPKLLDKLNDAVKNMHDFTNSV 255

  Fly   312 M----KYIQSA-----------------TERLKTQDPSLRAGEPSLVEKVILSQKD--EKIATIM 353
            :    :.:|.|                 ..|:...|..|:    |.::...||..|  |::.|.|
  Fly   256 ITERRELLQKAIADGGDADAALLNDVGQKRRMALLDVLLK----STIDGAPLSNDDIREEVDTFM 316

  Fly   354 ALDLILVGIDTISMAVCSMLYQLATRPVDQQKVHEELKRLL-PDPNTPLTIPLLDQMHHLKGFIK 417
                 ..|.||.:.::....|.||..|..|.:|.:|::.:: .|.:.|:|:.||.::.:|:..||
  Fly   317 -----FEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGELKYLECVIK 376

  Fly   418 EVFRMYSTVIGNGRTLMEDSVICGYQVPKGVQAVFPTIVTGNMEEYVTDAATFRPERWLKPQHGG 482
            |..|::.:|...||.:.:|:|:.|..:|.....:..........:|..|...|.|:|:...:
  Fly   377 ESLRLFPSVPIIGRYISQDTVLDGKLIPADSNVIILIYHAQRDPDYFPDPEKFIPDRFSMER--- 438

  Fly   483 TPGKLHPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKL 525
             .|::.|||..|:..|.|.|:|::||.|||:..::|::|:::|
  Fly   439 -KGEISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFEL 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp301a1	NP_610796.1	CYP24A1-like	110..547	CDD:410677	108/463 (23%)
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	105/452 (23%)