Protein Alignment Cyp301a1 and Cyp4c3

DIOPT Version :10

• Sequence 1: NP_610796.1
• Gene: Cyp301a1 / 36378
• FlyBaseID: FBgn0033753
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 546
• Identity: 127/546 - (23%)
• Similarity: 205/546 - (37%)
• Gaps: 138/546 - (25%)

  Fly    74 QIPGPKPIPILGNTWRLMPIIGQYTISDVAKISSLLHDR-YGRIV----RFGGLIGRPDLLFIYD 133
            :||||..:|.|||...:                ::.||. :.|::    .:|..||
  Fly    57 KIPGPAAMPFLGNAIEM----------------NVDHDELFNRVIGMQKLWGTRIG--------- 96

  Fly   134 ADEIEKCYRSEGPTP--FRPSM--PSLVKYKSVVRKDFFGDLGGVVGVHGEPW----------RE 184
               |.:.::...|..  |.|..  |.|...|.|.:...:..|        .||          |:
  Fly    97 ---INRVWQGTAPRVLLFEPETVEPILNSQKFVNKSHDYDYL--------HPWLGEGLLTSTDRK 150

  Fly   185 FRSRVQKPVLQLSTIRRYLQP----------LEVITEDFLVRCENLLDENQELPEDFDNEIHKWS 239
            :.||           |:.|.|          ::|..|...|....|..|...  |.|:  :..:.
  Fly   151 WHSR-----------RKILTPAFHFKILDDFIDVFNEQSAVLARKLAVEVGS--EAFN--LFPYV 200

  Fly   240 LECIGRVALDTRLG---CLESNLKPDSEPQ---------QIIDA--AKYALRNVATLELKAPYWR 290
            ..|...:..:|.:|   ..:||    ||.:         .|:.:  ||..|::.....|.|.|
  Fly   201 TLCTLDIVCETAMGRRIYAQSN----SESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEY-- 259

  Fly   291 YFPTPLWTRYVKNMNFFVGVCMKYIQSATERLKTQDPSLRAGEPSLVEKV--------------- 340
                .|...|:..::.|..:.::..::....|:..:.:.....|...:.|
  Fly   260 ----KLHQSYINTLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDA 320

  Fly   341 -----ILSQKD--EKIATIMALDLILVGIDTISMAVCSMLYQLATRPVDQQKVHEELKRLL-PDP 397
                 :||.:|  |::.|.|     ..|.||.|.|:...|:.|...|..|::|.|||..:. .|.
  Fly   321 SKEGTVLSNEDIREEVDTFM-----FEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDK 380

  Fly   398 NTPLTIPLLDQMHHLKGFIKEVFRMYSTVIGNGRTLMEDSVICGYQVPKGVQAVFPTIVTGNMEE 462
            .||.|:..|..|.:|:..||:..|::.:|....|.:.||..|.|..||.|.||:..|........
  Fly   381 ETPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPR 445

  Fly   463 YVTDAATFRPERWLKPQHGGTPGKLHPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKLEY 527
            .......|.|:.:|.....|.    ||||.:|:..|.|.|:|::||.||.:.:::.:||.||:|.
  Fly   446 VFPKPEQFNPDNFLPENCAGR----HPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEA 506

  Fly   528 NHKPLDYAV--TFMYAPDGPLRFKMT 551
            ..:..|..:  ..:..|...||.|:|
  Fly   507 VDRREDLTLLGELILRPKDGLRVKIT 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp301a1	NP_610796.1	CYP24A1-like	110..547	CDD:410677	115/504 (23%)
Cyp4c3	NP_524598.1	CYP4V-like	96..529	CDD:410753	111/486 (23%)