DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp301a1 and Cyp313b1

DIOPT Version :9

Sequence 1:	NP_610796.1	Gene:	Cyp301a1 / 36378	FlyBaseID:	FBgn0033753	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_001287239.1	Gene:	Cyp313b1 / 41019	FlyBaseID:	FBgn0037601	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	516	Identity:	114/516 - (22%)
Similarity:	194/516 - (37%)	Gaps:	119/516 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 WQNALPYN---QIPGPKPIPILGNTWRLM--PIIGQYTISDVAKISSLLHDRYGRIVR--FGGLI 123
            |.....|.   |:.||...|::|...::|  ....||.            |...|..:  |...:
  Fly    20 WSRRRYYKVAWQLRGPIGWPLIGMGLQMMNPETFLQYM------------DGLSRQFKAPFISWM 72

  Fly   124 GRPDLLFIYDADEIEKCYRSEGPTPFRPSMPSLVKYKSVVRKDFFGDLGGVVG----VHGEP-WR 183
            |....|:|.|...:|:...|...|.               :.||:..:...:|    ....| |.
  Fly    73 GTSCFLYINDPHSVEQILNSTHCTN---------------KGDFYRFMSSAIGDGLFTSSSPRWH 122

  Fly   184 EFRSRVQKPVLQLSTIRRYLQPLEVITEDFLVRCE-NLLDENQELPEDFDNEIHKWSLECIGRVA 247
            :.| |:..|......:..:|.......|..|.:.| ..:...:.|      ||::...:.:...|
  Fly   123 KHR-RLINPAFGRQILSNFLPIFNAEAEVLLQKLELEGVQHGKRL------EIYQILKKIVLEAA 180

  Fly   248 LDTRLGCLESNLKPDSEPQQIIDAAKYALRNVATLELKAPYWRYFPTPLWTR--YVKNMNFFVGV 310
            ..|.:| .:.|.:.|.  ...|..|...|..|....:.:| |.| |..::.|  ..:.....||:
  Fly   181 CQTTMG-KKMNFQHDG--SLCIFKAYNGLTEVCVKRMLSP-WLY-PDLIYRRSGLFRLQQKVVGI 240

  Fly   311 CMKYIQSATERL-----KTQDPSLRAGEPSL---------------VEKVILS---QKDEKIATI 352
            ...:|:...|.:     ...:|..:..|..:               ||:..||   .:||...||
  Fly   241 LFGFIEQLLEPIVSVVAANSNPDQQRSEMEMRGKSKAIFIEQVREHVERGQLSWQDVRDEANVTI 305

  Fly   353 MALDLILVGIDTISMAVCSMLYQLATRPVDQQKVHEELKRLLPDPNTPLTIPLLDQMHHLKGFIK 417
            .|.      .:|.|.|:...:..||..|..|:|:|:||...|| |:..:.:..|.::.:.:..|.
  Fly   306 AAT------FETTSTALYFTILCLAMHPCYQEKLHKELVTELP-PSGDINLEQLQRLEYTEMVIN 363

  Fly   418 EVFRMYSTV--------------IGNGRTLMEDSVICGYQVPKGVQAVFPTIVTGNMEEYVTD-- 466
            |..|:::.|              .|:|..|          :|:|.| :...|.....:|.|..
  Fly   364 EAMRLFAPVPMVLRSADQDIQLKRGDGEFL----------IPRGTQ-IGIDIYNMQRDERVWGPL 417

  Fly   467 AATFRPERWLKPQHGG--TPGKLHPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKL 525
            :.|:.|:     .|.|  :|.: |.||.:|:..|.|||:|.|:|.:.|::|||::.|:|::
  Fly   418 SRTYNPD-----AHFGLDSPQR-HAFAFVPFTKGLRMCIGYRYAQMLMKLLLARIFRSYRI 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp301a1	NP_610796.1	p450	76..530	CDD:299894	111/503 (22%)
Cyp313b1	NP_001287239.1	p450	33..474	CDD:299894	111/503 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24305
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100