Protein Alignment Cyp301a1 and Cyp12c1

DIOPT Version :9

• Sequence 1: NP_610796.1
• Gene: Cyp301a1 / 36378
• FlyBaseID: FBgn0033753
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001287109.1
• Gene: Cyp12c1 / 40037
• FlyBaseID: FBgn0036806
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 505
• Identity: 159/505 - (31%)
• Similarity: 264/505 - (52%)
• Gaps: 34/505 - (6%)

  Fly    64 SEWQNALPYNQIPGPKPIPILGNTWRLMPII---GQYTISDVAKISSLLHDRYGRIVRFGGLIGR 125
            |||:.|.|:.::|||       ..|:|....   |:|....:..:..|...::|.|....||.|.
  Fly    33 SEWEGAKPFTELPGP-------TRWQLFRGFQKGGEYHQLGMDDVMRLYKKQFGDICLIPGLFGM 90

  Fly   126 PDLLFIYDADEIEKCYRSEGPTPFRPSMPSLVKYKSVVRKDFFGDLGGVVGVHGEPWREFRSRVQ 190
            |..:|.::.:..||.||:||..|.|.....::.|::..:.:||.:..|:.| :|..|.:.||.|.
  Fly    91 PSTVFTFNVETFEKVYRTEGQWPVRGGAEPVIHYRNKRKDEFFKNCMGLFG-NGAEWGKNRSAVN 154

  Fly   191 KPVLQLSTIRRYLQPLEVITEDFLVRCENLLD-ENQELPEDFDNEIHKWSLECIGRVALDTRLGC 254
            ..::|...:..||:|::.:...|:.|...:.| |:||:|.||.|.|:..:.|.:..||||..||.
  Fly   155 PVLMQHRNVAIYLKPMQRVNRQFVNRIREIRDKESQEVPGDFMNTINHLTFESVATVALDRELGL 219

  Fly   255 L-ESNLKPDSEPQQIIDAAKYALRNVATLELKAPYWRYFPTPLWTRYVKNMNFFVGVCMKYIQSA 318
            | |:|  |..|..::....:..:.:...|.::...:||.|||.:.::.:.|:.....|..|:..|
  Fly   220 LREAN--PPPEASKLFKNIEVLMDSFFDLGVRPSLYRYIPTPTYKKFSRAMDEIFDTCSMYVNQA 282

  Fly   319 TERLKTQDPSLRAGE----PSLVEKVILSQKDEKIATIMALDLILVGIDTISMAVCSMLYQLATR 379
            .||:   |.....|:    .|::|:::  |.|.|:|.:||:|:::.|:||.|.|:..:|..||..
  Fly   283 IERI---DRKSSQGDSNDHKSVLEQLL--QIDRKLAVVMAMDMLMGGVDTTSTAISGILLNLAKN 342

  Fly   380 PVDQQKVHEELKRLLPDPNTPLTIPLLDQMHHLKGFIKEVFRMYSTVIGNGRTLMEDSVICGYQV 444
            |..||::.||:...|...::..|:..:..:.:|:..|||..|:|....||.|:...|.|:.||::
  Fly   343 PEKQQRLREEVLSKLTSLHSEFTVEDMKSLPYLRAVIKESLRLYPVTFGNARSAGADVVLDGYRI 407

  Fly   445 PKGVQAVFPTIVTGNMEEYVTDAATFRPERWLKPQHGGTPG-----KLHPFASLPYGYGARMCLG 504
            |||.:.:.........:.....|..|.|||||:.:......     .|:.|..||:|:|.|||:|
  Fly   408 PKGTKLLMTNSFLLKDDRLYPRAKEFIPERWLRRKDDDKSDVLMNKDLNAFIYLPFGFGPRMCVG 472

  Fly   505 RRFADLEMQILLAKLLRNYKLEYNH---KPLDYAVTFMYAPDGPLRFKMT 551
            :|..||||::.:|.|:||:.:|||:   ||  |...|:|.|:.||:||.|
  Fly   473 KRIVDLEMELTVANLVRNFHIEYNYSTEKP--YKCRFLYKPNIPLKFKFT 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp301a1	NP_610796.1	p450	76..530	CDD:299894	143/470 (30%)
Cyp12c1	NP_001287109.1	p450	45..502	CDD:278495	143/471 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	217	1.000	Domainoid score	I2609
eggNOG	1	0.900	-	-		E2759_KOG0159
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	219	1.000	Inparanoid score	I3547
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	1	1.000	-	-		FOG0000720
OrthoInspector	1	1.000	-	-		mtm6352
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
	9	8.970