Protein Alignment Cyp301a1 and Cyp6a2

DIOPT Version :10

• Sequence 1: NP_610796.1
• Gene: Cyp301a1 / 36378
• FlyBaseID: FBgn0033753
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 549
• Identity: 114/549 - (20%)
• Similarity: 206/549 - (37%)
• Gaps: 143/549 - (26%)

  Fly    75 IPGPKPIPILGNTWRLMPIIGQYTISDVAKISSLLHDRYGRIVRFGGLIGRPDLLFIYDADEIEK 139
            :|...|.|:.||      ::|       .:.:.::||                  |.||   ...
  Fly    31 VPHDAPHPLYGN------MVG-------FRKNRVMHD------------------FFYD---YYN 61

  Fly   140 CYRSEGPTPF-------RPS--MPSLVKYKSVVRKDF--FGDLG------------GVVGVHGEP 181
            .||..| .||       :|:  :......|:::.|||  |.|.|            .:..:.|:.
  Fly    62 KYRKSG-FPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHLFNLDGKK 125

  Fly   182 WREFRSRVQ------KPVLQLSTIRRYLQP-LEVITEDFLVRCENLLDENQELPEDFDNEI---H 236
            |::.|.|:.      |......|:.:..:. ::||||.........:.|.:||...|..::   .
  Fly   126 WKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVIGTC 190

  Fly   237 KWSLEC------------IG-RVALDTRLG-----------CLESNLKPDSEPQQIIDAAKYALR 277
            .:.:||            :| :|..|.|.|           .|.|.|:....|:   |..::.:|
  Fly   191 AFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMRMMPE---DVHQFFMR 252

  Fly   278 NV-ATLELKAPYWRYFPTPLWTRYVKN--MNFFVGVCMKYIQSATERLKTQDPSLRAGEPSLVEK 339
            .| .|:.|:..          ..:.:|  ||..:.:..|                  |..:|...
  Fly   253 LVNDTIALRER----------ENFKRNDFMNLLIELKQK------------------GRVTLDNG 289

  Fly   340 VILSQKDEKIATIMALDLILVGIDTISMAVCSMLYQLATRPVDQQKVHEELKRLLPDPNTPLTIP 404
            .::...|............:.|.:|.|..:...||:||.....|.::..|::.:|.:....||..
  Fly   290 EVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYE 354

  Fly   405 LLDQMHHLKGFIKEVFRMYSTVIGNGRTLMEDSVICGYQ---VPKGVQAVFPTIVTGNMEEYVTD 466
            .:..|.:|...|.|..|:|:.|....|..:.|.|:.|::   :.||.|.:.|.......|:...:
  Fly   355 SIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPN 419

  Fly   467 AATFRPERWLKPQHGGTPGKLHPFAS---LPYGYGARMCLGRRFADLEMQILLAKLLRNYKL--- 525
            ..||.|||:       :|.|:....|   ||:|.|.|.|:|.||..::.:|.||:::..:::
  Fly   420 PETFDPERF-------SPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVC 477

  Fly   526 EYNHKPLDYA-VTFMYAPDGPLRFKMTRV 553
            :....||.|: ::.:....|.:..::.|:
  Fly   478 DTTEIPLKYSPMSIVLGTVGGIYLRVERI 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp301a1	NP_610796.1	CYP24A1-like	110..547	CDD:410677	107/506 (21%)
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	99/468 (21%)