Protein Alignment Cyp301a1 and Cyp11b3

DIOPT Version :10

• Sequence 1: NP_610796.1
• Gene: Cyp301a1 / 36378
• FlyBaseID: FBgn0033753
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_861545.2
• Gene: Cyp11b3 / 353498
• RGDID: 727886
• Length: 498
• Species: Rattus norvegicus
• Alignment Length: 526
• Identity: 118/526 - (22%)
• Similarity: 219/526 - (41%)
• Gaps: 100/526 - (19%)

  Fly    66 WQ-----NALPYNQIPGPKPIPILGNTWRLMPIIGQYTISDVAKISSLLHDR------------- 112
            ||     .||.......||       |.:....|.||:.:...|:..:|.::
  Rat    14 WQCLHRTRALGSTATQAPK-------TLKPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQAF 71

  Fly   113 --YGRIVRFGGLIGRPDLLFIYDADEIEKCYRSEGPTPFRPSMPSLVKYKSV--VRKDFFGDLGG 173
              .|.|.|...  |...::.:...::.||.::.|...|.|.::.|.|.::.:  :|:       |
  Rat    72 QELGPIFRHSA--GGAQIVSVMLPEDAEKLHQVESILPRRMTLESWVAHRELRGLRR-------G 127

  Fly   174 VVGVHGEPWREFRSRVQKPVLQLSTIRRYLQPLEVITEDFLVRCENLLDEN--QELPEDFDNEIH 236
            |..::|..||..|.::...:|....::.::..::|:..||:...:..:.||  ..:..|..:.:.
  Rat   128 VFLLNGADWRFNRLQLNPNMLSPKAVQSFVPFVDVVARDFVENLKKRMLENVHGSMSMDIQSNVF 192

  Fly   237 KWSLECIGRVALDTRLGCLESNLKPDSEPQQIIDAAKYALRNVATLE-LKAPYWRYFPTPLWTRY 300
            .:::|....|....|||....:|||:|  .:.|.|.....::...|. |.....|:..|.:|..:
  Rat   193 NYTMEASHFVISGERLGLTGHDLKPES--LKFIHALHSMFKSTTQLMFLPKNLTRWTSTQVWKGH 255

  Fly   301 VKNMNF---FVGVCMKYIQSATERLKTQDPSLRAGEPSLVEKVILSQKDEKIATIMALDLILVGI 362
            .::.:.   :|..|:|.:.......:.|..|:      :.|.|..|..........:::||...:
  Rat   256 FESWDIISEYVTKCIKNVYRELAEGRQQSWSV------ISEMVAQSTLSMDAIHANSMELIAGSV 314

  Fly   363 DTISMAVCSMLYQLATRPVDQQKVHEEL----KRLLPDPNTPLT-IPLLDQMHHLKGFIKEVFRM 422
            ||.::::...|::||..|..||.:.:|.    ..:..:|...:: :||      |:..:||..|:
  Rat   315 DTTAISLVMTLFELARNPDVQQALRQESLAAEASIAANPQKAMSDLPL------LRAALKETLRL 373

  Fly   423 YSTVIGNG--RTLMEDSVICGYQVPKGV------------QAVFPTIVTGNMEEYVTDAATFRPE 473
            |.  ||:.  |.:..|.|:..|.||.|.            .||||     ..|.|:       |:
  Rat   374 YP--IGSSLERIVDSDLVLQNYHVPAGTLVIIYLYSMGRNPAVFP-----RPERYM-------PQ 424

  Fly   474 RWLKPQHGGTPGKLHPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKLE-YNHKPLDYAVT 537
            |||:        :...|..|.:|:|.|.|||||.|::|:.:||..:|:.:::| ...:.:..|..
  Rat   425 RWLE--------RKRSFQHLAFGFGVRQCLGRRLAEVEVLLLLHHMLKIFQVETLRQEDVQMAYR 481

  Fly   538 FMYAPD 543
            |:..|:
  Rat   482 FVLMPN 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp301a1	NP_610796.1	CYP24A1-like	110..547	CDD:410677	106/477 (22%)
Cyp11b3	NP_861545.2	None