Protein Alignment Cyp301a1 and Cyp12d1-d

DIOPT Version :10

• Sequence 1: NP_610796.1
• Gene: Cyp301a1 / 36378
• FlyBaseID: FBgn0033753
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_995812.1
• Gene: Cyp12d1-d / 2768720
• FlyBaseID: FBgn0053503
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 534
• Identity: 158/534 - (29%)
• Similarity: 270/534 - (50%)
• Gaps: 52/534 - (9%)

  Fly    39 SSTGVATCPHLADSEEASAPRIHSTSEWQNALPYNQIPGPKPIPILGNTWRLMPII---GQYTIS 100
            ||...:...|  :..::|....|.|        |::||.|       |.::.|...   |::..:
  Fly    19 SSRSASVLAH--EQAKSSITEEHKT--------YDEIPRP-------NKFKFMRAFMPGGEFQNA 66

  Fly   101 DVAKISSLLHDRYGRIVRFGGLIGRPDLLFIYDADEIEKCYRSEGPTPFRPSMPSLVKYKSVVRK 165
            .:.:.:|.:..|||.|....|:.||.|.:..::..:||..:|:||..|.|..:.|:|.::..||.
  Fly    67 SITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRP 131

  Fly   166 DFFGDLGGVVGVHGEPWREFRSRVQKPVLQLSTIRRYLQPLEVITEDFLVRCENLLD-ENQELPE 229
            |.:|::.|:|....|.|.:.||.:....:|...:|.|.:||..|..:|:.|.:.:.| :..|:||
  Fly   132 DVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPE 196

  Fly   230 DFDNEIHKWSLECIGRVALDTRLGCLESNLKPDSEPQQIIDAAKYALRNVATLELKAPYWRYFPT 294
            ||.:||.:...|.:|.||.|.::|.:..| :.:|:...:...::...|....|:::...|:...|
  Fly   197 DFTDEISRLVFESLGLVAFDRQMGLIRKN-RDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIIST 260

  Fly   295 PLWTRYVKNMNFFVGVCMKYI---QSATERLKTQDPSLRAGEP----SLVEKVILSQKDEKIATI 352
            |.:.:..:.:|..:.|..|.:   |.|.|:.:      :|||.    |::|:  |.:.|.|:|.|
  Fly   261 PTYRKMKRTLNDSLNVSQKMLKENQDALEKRR------QAGEKINSNSMLER--LMEIDPKVAVI 317

  Fly   353 MALDLILVGIDTISMAVCSMLYQLATRPVDQQKVHEELKRLLPDPNTPLTIPLLDQMHHLKGFIK 417
            |:||::..|:|..:..:.::|..|:..|..|.|:.|||..::|..::.|....:..|.:|:..||
  Fly   318 MSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIK 382

  Fly   418 EVFRMYSTVIGNGRTLMEDSVICGYQVPKGVQAVFPTIVTGN---MEE--YVTDAATFRPERWLK 477
            |..|.|....|..||...|.::.||:||||.     |::.|:   |:|  |......|.|||||:
  Fly   383 ETLRYYPNGFGTMRTCQNDVILSGYRVPKGT-----TVLLGSNVLMKEATYYPRPDEFLPERWLR 442

  Fly   478 PQHGGTPGKLHPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKLEYNH---KPLDYAVTFM 539
            ....|...::.||..||:|:|.|||:|:|..||||:..:|||:||:.:|:|.   :|  :...|:
  Fly   443 DPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRP--FKTMFL 505

  Fly   540 YAPDGPLRFKMTRV 553
            ..|.....||.|.:
  Fly   506 MEPAITFPFKFTDI 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp301a1	NP_610796.1	CYP24A1-like	110..547	CDD:410677	141/452 (31%)
Cyp12d1-d	NP_995812.1	CYP24A1-like	76..515	CDD:410677	141/454 (31%)