Protein Alignment Cyp301a1 and Cyp24a1

DIOPT Version :9

• Sequence 1: NP_610796.1
• Gene: Cyp301a1 / 36378
• FlyBaseID: FBgn0033753
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_034126.1
• Gene: Cyp24a1 / 13081
• MGIID: 88593
• Length: 514
• Species: Mus musculus
• Alignment Length: 514
• Identity: 139/514 - (27%)
• Similarity: 232/514 - (45%)
• Gaps: 80/514 - (15%)

  Fly    33 RAQCRESSTGVATCPHLADSEEASAPRIHSTSEWQNALPYNQIPGPKPIPILGNTWRLMPIIGQY 97
            :|..:.:...|..||.:.|.|..:.               ..:|||...|:||:   |:.|..:.
Mouse    31 KAHVKRAPKEVPLCPLMTDGETRNV---------------TSLPGPTNWPLLGS---LLEIFWKG 77

  Fly    98 TISDVAKISSLLHDRYGRIVR-----FGGL-IGRPDLLFIYDADEIEKCYRSEGPTPFRPSMPSL 156
            .:.......:..|.:||:|.|     |..: :|.|.||        |..||:|...|.|..:...
Mouse    78 GLKKQHDTLAEYHKKYGQIFRMKLGSFDSVHLGSPSLL--------EALYRTESAHPQRLEIKPW 134

  Fly   157 VKYKSVVRKDFFGDLGGVVGVHGEPWREFRSRVQKPVLQLSTIRRYLQPLEVITEDFLVRCENLL 221
            ..|     :|...:..|::.:.|:.|:..||..||.:::...|.:..:.:..:..||:.:.:.|.
Mouse   135 KAY-----RDHRNEAYGLMILEGQEWQRVRSAFQKKLMKPVEIMKLDKKINEVLADFMGQIDELR 194

  Fly   222 DENQELPEDFDNEIHKWSLECIGRVALDTRLGCLESNLKPDSEPQQIIDAAKYALRNVATL---- 282
            ||...: :|..:|::|||.|.|..|..:.|.|.|:.:  .:.|....|.|.|..:.....:
Mouse   195 DERGRI-QDLYSELNKWSFESICLVLYEKRFGLLQKD--TEEEALTFIAAIKTMMSTFGKMMVTP 256

  Fly   283 -----ELKAPYWRYFPTPLWTRYVKNMNFFVGVCMKYIQSATERLK--TQDPSLRAGEPSLVEKV 340
                 .|....|:.. |..|....|:    |..|:.:      ||:  :|.|    |...|.:
Mouse   257 VELHKRLNTKVWQAH-TLAWDTIFKS----VKPCIDH------RLERYSQQP----GADFLCD-- 304

  Fly   341 ILSQ----KDEKIATIMALDLILVGIDTISMAVCSMLYQLATRPVDQQKVHEELKRLLPDPNTPL 401
            |..|    |.|..|.:  .:|.|..::|.:.::..:||.|:..|..||::..|::.:|||..||.
Mouse   305 IYQQDHLSKKELYAAV--TELQLAAVETTANSLMWILYNLSRNPQVQQRLLREIQSVLPDNQTPR 367

  Fly   402 TIPLLDQMHHLKGFIKEVFRMYSTVIGNGRTLMEDSVICGYQVPKGVQAVFPTIVTGNMEEYVTD 466
            ...:.: |.:||..:||..|:..:|....|||.:.:|:..|.:|||......|.|.|:.|:...|
Mouse   368 AEDVRN-MPYLKACLKESMRLTPSVPFTTRTLDKPTVLGEYTLPKGTVLTLNTQVLGSSEDNFED 431

  Fly   467 AATFRPERWLKPQHGGTPGKLHPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKL 525
            |..|||||||:.:.     |::|||.||:|.|.|||:|||.|:|::.:.|..:::.|.:
Mouse   432 ADKFRPERWLEKEK-----KINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIIQKYNI 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp301a1	NP_610796.1	p450	76..530	CDD:299894	133/471 (28%)
Cyp24a1	NP_034126.1	p450	59..513	CDD:278495	133/471 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	190	1.000	Domainoid score	I3255
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	196	1.000	Inparanoid score	I3800
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	1	1.000	-	-		FOG0000720
OrthoInspector	1	1.000	-	-		mtm8705
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.870