Protein Alignment Cyp301a1 and Cyp11b1

DIOPT Version :9

• Sequence 1: NP_610796.1
• Gene: Cyp301a1 / 36378
• FlyBaseID: FBgn0033753
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001028401.2
• Gene: Cyp11b1 / 110115
• MGIID: 88583
• Length: 501
• Species: Mus musculus
• Alignment Length: 521
• Identity: 123/521 - (23%)
• Similarity: 214/521 - (41%)
• Gaps: 110/521 - (21%)

  Fly    84 LGNTWRLMP-------IIGQYTISDVAKISSLLHDR---------------YGRIVRFGGLIGRP 126
            ||.|..|.|       .|.||:.:...|:..:|.::               .|.|.|..  :|:.
Mouse    26 LGTTATLAPKTLQPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQVFRELGPIFRHS--VGKT 88

  Fly   127 DLLFIYDADEIEKCYRSEGPTPFRPSMPSLVKYKSVVRKDFFGDLGGVVGVHGEPWREFRSRVQK 191
            .::|:...:::||.|:.|...|.|..:.|.     :|.::..|...||..::|..|...|.::..
Mouse    89 QIVFVTLPEDVEKLYQVESTHPCRMPLESW-----IVHRELRGLGRGVFLLNGPEWYFNRLQLNP 148

  Fly   192 PVLQLSTIRRYLQPLEVITEDFLVRCENLLDENQE-----LPEDFDNEIHKWSLECIGRVALDTR 251
            .||....:::::..::.|..||:   :||..:..|     ...||.:.:..:::|....|....|
Mouse   149 NVLSPKAVQKFVPLVDGIARDFV---DNLKKKMLESVHGSFSMDFQSSVFNYTIEASHFVLFGER 210

  Fly   252 LGCLESNLKPDSEPQQIIDAAKYALRNVATLE-----------LKAPYWRYFPTPLWTRYVKNMN 305
            ||.:..:|.|||            |:.:.||.           |.....|:..|.:|...:::.:
Mouse   211 LGLIGRDLSPDS------------LKFLHTLHSMFKTTTQLLYLPRSLTRWTSTRVWKENLESWD 263

  Fly   306 F---FVGVCMKYIQSATERLKTQDPSLRAGEPS--LVEKVILSQKDEKIATIMA--LDLILVGID 363
            |   :|..|:|.:..          .|..|.|.  .|...:::::...:..|.|  ::||....|
Mouse   264 FISEYVTKCIKNVYR----------ELAEGRPQSWSVTAELVAERTLSMDAIQANSMELIAGSTD 318

  Fly   364 TISMAVCSMLYQLATRPVDQQKVHEEL----KRLLPDPNTPLT-IPLLDQMHHLKGFIKEVFRMY 423
            |.|..:....::||..|..||.:.:|.    ..:..:|...:: :||      |:..:||..|:|
Mouse   319 TTSTPLVMTFFELARNPDVQQALRQESLAAEASIAANPQKAMSDLPL------LRAALKETLRLY 377

  Fly   424 STVIGNGRTLMEDSVICGYQVPKGVQAVFPTIVTGNMEEYVTDAATF------RPERWLKPQHGG 482
            .......|.|..|.|:..|.||.|      |::..|:.....:.|.|      .|:|||:
Mouse   378 PVGTFLERILSSDLVLQNYHVPAG------TVLNVNLYSMGRNPAVFPRPERYMPQRWLE----- 431

  Fly   483 TPGKLHPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKLEYNHK-PLDYAVTFMYAP-DGP 545
               :...|..|.:|:|.|.|||||.|:.||.:||..:|:::.:|...| .:..|..|:..| ..|
Mouse   432 ---RKRSFKHLAFGFGVRQCLGRRLAEAEMMLLLHHVLKSFHVETQEKEDVRMAYRFVLMPSSSP 493

  Fly   546 L 546
            |
Mouse   494 L 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp301a1	NP_610796.1	p450	76..530	CDD:299894	117/501 (23%)
Cyp11b1	NP_001028401.2	p450	44..497	CDD:278495	117/503 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8705
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820