Protein Alignment Cyp301a1 and cyp24a1

DIOPT Version :9

• Sequence 1: NP_610796.1
• Gene: Cyp301a1 / 36378
• FlyBaseID: FBgn0033753
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_012808417.2
• Gene: cyp24a1 / 100497429
• XenbaseID: XB-GENE-479201
• Length: 508
• Species: Xenopus tropicalis
• Alignment Length: 531
• Identity: 143/531 - (26%)
• Similarity: 255/531 - (48%)
• Gaps: 75/531 - (14%)

  Fly    41 TGVATCPHLADSEEASAPRIHSTSEWQNALPYN--QIPGPKPIPILGNTWRLMPIIGQYTISDVA 103
            |..|.|.  ...||..||         ::.|::  .:|||..:||||:   |:.|:.:..:....
 Frog    27 TATAVCD--LKEEELPAP---------SSCPHSLAALPGPTKLPILGS---LLDILRKGGLKRQH 77

  Fly   104 KISSLLHDRYGRIVR-----FGGL-IGRPDLLFIYDADEIEKCYRSEGPTPFRPSMPSLVKYKSV 162
            :..:..|.::|:|.|     |..: ||.|.||        |..||.|...|.|..:.....|
 Frog    78 EALASYHKQFGKIFRMKLGSFDSVHIGAPCLL--------EALYREESNYPKRLEIKPWKAY--- 131

  Fly   163 VRKDFFGDLGGVVGVHGEPWREFRSRVQKPVLQLSTIRRYLQPLEVITEDFLVRCENLLDENQEL 227
              :|:..:..|::.:.|:.|:..||..|:.:::.:.:.:....:..:..||:.|.:::.||:..:
 Frog   132 --RDYRDEAYGLLILEGKDWQRVRSAFQQKLMKPTEVGKLDTKINEVLVDFMKRIDSVCDEDGTI 194

  Fly   228 PEDFDNEIHKWSLECIGRVALDTRLGCLESNLKPDSEPQQIIDAAK-----YALRNVATLELKAP 287
             ||...|::|||||.|..|..:.|.|.|:.||  ..|.|..|.|.|     :.|..|..:||.
 Frog   195 -EDLYCELNKWSLESICLVLYEKRFGFLQPNL--GEEAQNFITAIKMMMSTFGLMMVTPVELH-- 254

  Fly   288 YWRYFPTPLWTRYVKNMNFFVGVCMKYIQSATERLKTQDPSLRAGEP---SLVEKVILSQKDEKI 349
              :...|.:|..:....:........:|.....:|     |.:..|.   ::.....||:| |..
 Frog   255 --KSLNTKIWKDHTHAWDSIFKTAKCHIDRRLTKL-----SSKGSEDFLCTIYNDSKLSKK-EMY 311

  Fly   350 ATIMALDLILVGIDTISMAVCSMLYQLATRPVDQQKVHEELKR-LLPDPNTPLTIPLLD---QMH 410
            |||  .::::..::|.:.::...::.::..|..|:|:.||::. ||||     .:|..|   .|.
 Frog   312 ATI--TEMLIGAVETTANSLLWAIFNISRNPHIQKKLLEEIESVLLPD-----QVPTADDIRNMP 369

  Fly   411 HLKGFIKEVFRMYSTVIGNGRTLMEDSVICGYQVPKGVQAVFPTIVTGNMEEYVTDAATFRPERW 475
            :||..:||..|:..::....|||.:::|:..|.:|||......:.|.|:.:|...:...||||||
 Frog   370 YLKACLKESMRITPSIPFTTRTLDKETVLGDYVLPKGTVLTINSHVLGSNQECFDNWNQFRPERW 434

  Fly   476 LKPQHGGTPGKLHPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKL-EYNHKPLD--YAVT 537
            |:.::     .::|||.:|:|.|.|||:|||.|:|::|:.|..|:|.|:: ..::.|::  :..|
 Frog   435 LQQKN-----TINPFAHVPFGIGKRMCIGRRLAELQLQLTLCWLIRKYEIVATDNDPVETLHLGT 494

  Fly   538 FMYAPDGPLRF 548
            .|.:.:.|:.|
 Frog   495 LMPSRELPVAF 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp301a1	NP_610796.1	p450	76..530	CDD:299894	130/472 (28%)
cyp24a1	XP_012808417.2	CYP24A1	84..502	CDD:410738	124/455 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	193	1.000	Domainoid score	I3126
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I3591
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	1	1.000	-	-		FOG0000720
OrthoInspector	1	1.000	-	-		mtm9361
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970