| Sequence 1: | NP_523716.2 | Gene: | fra / 36377 | FlyBaseID: | FBgn0011592 | Length: | 1526 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001138424.1 | Gene: | SDK2 / 54549 | HGNCID: | 19308 | Length: | 2172 | Species: | Homo sapiens |
| Alignment Length: | 1729 | Identity: | 369/1729 - (21%) |
|---|---|---|---|
| Similarity: | 620/1729 - (35%) | Gaps: | 487/1729 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 12 LWNWLLSSCLIFQLIGSSLASQALS--FTLEP-QDAVVPEGHSVLLQCAGTASIGRGGKSKSNLP 73
Fly 74 SSVSIRWRGPDGQDLVIVGDTFRTQLKNGSLYISSVEENRGLTGAYQCLLTAEGVGSILSRPALV 138
Fly 139 AIVRQPDLNQDFLETYLLPGQTAYFRCMLGEANWQEGVKH----------------------SVQ 181
Fly 182 WLKDDLPLPLDKLRMVVLPNGALEIDEVGPSDRGSYQCNVTS-----GSSSRLSSKTNLNIKKPS 241
Fly 242 DPGAENSVAPSFLVGPSPKTVREGDT-VTLDCVANGVP--KPQIKWLRNGMDLD--FNDLDSRFS 301
Fly 302 IVG-TGSLQISSAEDIDSGNYQCRA---SNTVDSLDAQATVQVQEPPKFIKAP-KDTTAHEKDEP 361
Fly 362 ELKCDIWGKPKPVIRWLKNGDLITPND---YMQLVDGHNLKILGLLNSDAGMFQCVGTNAAGSVH 423
Fly 424 AAARLRVVPQGVKIKKRKSQGHSTKSLQTFDNLTKRRKPFNS------GEQLRTKSGGSFPFPDE 482
Fly 483 DDDLDDNDSGTTRLRIPSGKLPKFEQPLNDRRFNILNAGSALPLDNQSKSYEDDDDDYDEDDPAK 547
Fly 548 EALLEAYKQG-EDAHKILDSWQQSKSKKSQQQ----KQSPAS-PDSPEQDPSV------------ 594
Fly 595 ----PHP------------------------------GGKPLDSG-LQAR-LPSQPRDLVAQI-- 621
Fly 622 VKSRFVTLSWVEPLQNAGDVVYYTVYYKMNNSEREQKMVTKSHDDQQVNIQSLLPGRTYQFRVEA 686
Fly 687 NTNFGSGASSAPLEVSTQPEVNIAGPPRNFEGYARSHKEIYVKWEEPT------VTNGEILKYRV 745
Fly 746 ------YYSENDSGADLYHDSTALEAVLTELRPHTDYVISVVPFNRNGMGDSSAEIRVKTFSSTP 804
Fly 805 SEPPNNVTLEVTSSSSI--------------------TVHWEPPAEE------------------ 831
Fly 832 ---------------------------------------------------------------DR 833
Fly 834 NGQITGYKIRYRKF-KDAPQVKSTPANIRY-FELSNLDRNAEYQVKIAAMTVNGSGPFTEWNRAN 896
Fly 897 TLENDLDETQVPGKPIWISI-HPGANNIALHWGPPQHPEIKIRNYVLGWGRGIPDENTIELKETE 960
Fly 961 RYHILKNLESNMD--------------YVVSLRARNVKGDGPPIYDNIKTRDEEPVDAPTPLEVP 1011
Fly 1012 VGLRAITMSSSSIVVYWI---DTMLNKNQHVTDNRHYTVSYGIT-GSNRYRYH---NTTDLNCMI 1069
Fly 1070 NDLRPNTQYEFAVKVVKGRRESSWSMSVLNSTYQNVPVTPPREVTVRLDEMNPPTVIVQW--IPP 1132
Fly 1133 KHTLGQITGYNIYY-TTDTTKRDRDWSVEAFAGEETMLMLPNLKPYTTYYFKVQARTTKGANNAP 1196
Fly 1197 FSALVSYTTSAAVTMQEPDTIAKGIDNEK-----LLYIIIAATAVVLLVVLLGVLLLCRRKPQSS 1256
Fly 1257 PEHTKKSYQKNNVGVPKPPDLWIHHDQMELKNIDKGLHTVTPVCSDGASSSGALTLPRSVVHSEY 1321
Fly 1322 EVETPVP-GHVTNSLDKRSYVPGYMTTSMNGTMERPQYPRTQYSHQNRSHMTMEAGLSQQSLT-- 1383
Fly 1384 -QPQSNSMA-------QTPEHPYGGYDANFCNAGNAAA------------------GNGCVSTIE 1422
Fly 1423 SSKRGHPLKSF-SVPGPPPTGGATPVTKH-TPAVTIRPQ 1459 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| fra | NP_523716.2 | Ig | 36..140 | CDD:299845 | 23/106 (22%) |
| Ig | <180..222 | CDD:299845 | 11/41 (27%) | ||
| IG_like | 257..340 | CDD:214653 | 31/91 (34%) | ||
| IGc2 | 264..327 | CDD:197706 | 25/71 (35%) | ||
| I-set | 344..430 | CDD:254352 | 32/89 (36%) | ||
| Ig | 363..428 | CDD:299845 | 25/67 (37%) | ||
| FN3 | 611..703 | CDD:238020 | 25/93 (27%) | ||
| FN3 | 711..799 | CDD:238020 | 24/99 (24%) | ||
| FN3 | 806..897 | CDD:238020 | 30/193 (16%) | ||
| FN3 | 908..989 | CDD:238020 | 17/95 (18%) | ||
| FN3 | 1011..1097 | CDD:238020 | 19/92 (21%) | ||
| FN3 | 1109..1205 | CDD:238020 | 23/98 (23%) | ||
| Neogenin_C | 1273..1521 | CDD:284094 | 41/218 (19%) | ||
| SDK2 | NP_001138424.1 | Ig | 27..109 | CDD:299845 | 22/124 (18%) |
| IG_like | 40..109 | CDD:214653 | 18/111 (16%) | ||
| I-set | 120..203 | CDD:254352 | 14/83 (17%) | ||
| Ig | 132..210 | CDD:299845 | 14/78 (18%) | ||
| IG_like | 222..304 | CDD:214653 | 30/90 (33%) | ||
| IGc2 | 233..286 | CDD:197706 | 23/61 (38%) | ||
| I-set | 308..397 | CDD:254352 | 32/89 (36%) | ||
| Ig | 326..394 | CDD:143165 | 25/68 (37%) | ||
| I-set | 402..492 | CDD:254352 | 27/118 (23%) | ||
| Ig | 416..492 | CDD:299845 | 22/102 (22%) | ||
| Ig | 502..586 | CDD:299845 | 13/83 (16%) | ||
| IG_like | 502..586 | CDD:214653 | 13/83 (16%) | ||
| FN3 | 590..681 | CDD:238020 | 24/90 (27%) | ||
| FN3 | 693..786 | CDD:238020 | 24/98 (24%) | ||
| FN3 | 794..890 | CDD:238020 | 13/95 (14%) | ||
| FN3 | 895..983 | CDD:238020 | 17/91 (19%) | ||
| FN3 | 993..1087 | CDD:238020 | 19/103 (18%) | ||
| FN3 | 1099..1194 | CDD:238020 | 20/97 (21%) | ||
| FN3 | 1201..1290 | CDD:238020 | 23/108 (21%) | ||
| FN3 | 1301..1394 | CDD:238020 | 19/127 (15%) | ||
| FN3 | 1400..1484 | CDD:238020 | 13/91 (14%) | ||
| FN3 | 1503..1616 | CDD:238020 | 10/23 (43%) | ||
| FN3 | 1626..1719 | CDD:238020 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1707..1729 | ||||
| FN3 | 1724..1805 | CDD:238020 | |||
| FN3 | 1837..1916 | CDD:238020 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2039..2067 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2098..2172 | ||||
| PDZ-binding. /evidence=ECO:0000250|UniProtKB:Q6V4S5 | 2166..2172 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG4221 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||