Protein Alignment fra and plum

DIOPT Version :9

• Sequence 1: NP_523716.2
• Gene: fra / 36377
• FlyBaseID: FBgn0011592
• Length: 1526
• Species: Drosophila melanogaster
• Sequence 2: NP_001163744.1
• Gene: plum / 43197
• FlyBaseID: FBgn0039431
• Length: 1298
• Species: Drosophila melanogaster
• Alignment Length: 1583
• Identity: 287/1583 - (18%)
• Similarity: 489/1583 - (30%)
• Gaps: 569/1583 - (35%)

  Fly    87 DLVIVGDTFRTQ----LKNGSLYISSVEENRGLTGAYQCLLTAEGVGSILSR-----PALVAIV- 141
            |:|:...::|..    ..||:|.:.:   |...:|.|.|.:..:....|..|     |.|..:.
  Fly   102 DVVVEQVSYRKNDFFIYDNGTLRLPT---NEKASGEYYCKIEWDESAVISDRITVEYPVLKRLFP 163

  Fly   142 -RQPDLNQDFLETYLLPGQTAYFRCMLGEANWQEGVKHSVQWLKDDLPLPLDKLRMVVLPNGALE 205
             :|...|...||...|.....:........:|..|        .|.|   .:....::|.||.|.
  Fly   164 GQQQAANISALENKPLVLSCPFLSVPAARFSWYFG--------NDSL---TNDNSALILTNGTLI 217

  Fly   206 IDEVGPSDRGSYQCNVTSGSSSRLSSKTN------LNIKKPSDPG--------------AENSVA 250
            :..:.....|.|:|    .:.:..:|||:      |.: :|.|..              :|..:.
  Fly   218 LRHLRLEQAGKYKC----VAQNTFASKTHRQFIWQLQV-EPKDATFYPKNEAGITETAVSEAQLL 277

  Fly   251 PSFLVGPSPKTVREGDTVTLDC--VANGVP------KPQIKWLRNGMDLDFNDLDSRFSIVGTGS 307
            |:|  ..:...|..|.:|.|.|  ||:.||      .|..|.:|    |..|.:  .:||.   :
  Fly   278 PAF--QNATVFVPAGGSVLLQCHAVADFVPIVWYLQPPNNKMVR----LSNNSV--AYSIT---N 331

  Fly   308 LQISSAEDIDSGNYQCRASNTVDSLDAQ-ATVQVQEPPKFIKAPKDTTAHEKDEPELKCDIWGKP 371
            ..|:..|    |.|.|     :..|:.| ..|.|..||:.:........:......|.|...|.|
  Fly   332 ASIARHE----GRYSC-----ITPLETQNFQVIVTTPPRIVSRLPVEVVYIGLSRTLTCRAEGHP 387

  Fly   372 KPVIRWLKNGDLITPNDYMQLVDGHNLKILGLLNSDAGMFQCVGTNAAGSVHAAARLRVVPQGVK 436
            :|.|.|..||..:. :.|.:.:.|:.|.:....:.:.|::|||..|.||...|...||...|..:
  Fly   388 EPSITWYHNGVHLN-SSYTRYISGNELHVHSFDSKEEGIYQCVARNVAGEDSATGELRFNRQLEE 451

  Fly   437 I---KKRKSQGHSTKSLQ-TFDNLT---------KRRKPFNSGEQLRTKSGGSFPFPDEDDDLDD 488
            :   :..:...||..|:. |||:.|         .|..|         .|..||         ..
  Fly   452 VNPLQNIRCYPHSFHSINITFDSRTLTSMFVVYIVRNNP---------HSWTSF---------SP 498

  Fly   489 NDSGTTRLRIPSGKLPKFEQ---------PLNDRRFNILNAGSALPLDNQSKSYEDDDDDYDEDD 544
            .....|...:.|..||.:|.         |..:.|     .|:.:|......|.        ...
  Fly   499 MKLNQTSYVVISTDLPVYEPFALITRVLFPTTEVR-----TGTLVPQQMILSSL--------RST 550

  Fly   545 P----AKEALLEAYKQGEDAHKILDSWQQS--KSKKSQQQKQSPASPDSPEQDPSVPHPGGKPLD 603
            |    .:..:|.....|.|.   ...|.|.  ::||....:.|        .:.:.||| .:.|:
  Fly   551 PVTCCTQGLMLRPIAVGNDT---FVKWSQGQLENKKYFILQFS--------INHTHPHP-AQLLN 603

  Fly   604 SGLQARLPS--QPRDLVAQIVKSRFVTLSWVEPL-QNAGDVVYYTVYYKMNNSEREQKMVTKS-- 663
            ..||..|.|  :..|.|..       .|:.::|| |:|...|       :.|.|.|..:|..:
  Fly   604 GSLQGTLTSVEEKADQVRH-------HLTEIQPLNQSAAATV-------LRNVEHEDNVVDDTLE 654

  Fly   664 -HDD-----QQVNIQSLLPGRTYQFRVEANTNFGSGASSAPLEVSTQPEVNIAGPPRNFEGYARS 722
             .||     ...::..:|..|..:.::..            |.::|:.|  ..|  ::|.
  Fly   655 LEDDIFSLVVDASVTGILLQRFTRIKMRV------------LIITTENE--FLG--QDFR----- 698

  Fly   723 HKEIYVKWEEPTVTNG----EILKYRVYYSENDSGADLYHDSTALEAVLTELRPHTDYVISVVPF 783
                ||:|:  .:.||    ..:.:|:...|:.:.|..:.||.....|   |..||:
  Fly   699 ----YVQWK--IIENGTSEQSNMPFRLVTRESRALAFKFLDSLNETCV---LECHTE-------- 746

  Fly   784 NRNGMGDSSAEIRVKTFSSTPSEPPNNVTLEVTSSSSITVHWEPPAEEDRNGQITGYKIRYRKFK 848
                         ::...|.||:.|..                    :|||
  Fly   747 -------------IQAQMSLPSQDPKC--------------------QDRN-------------- 764

  Fly   849 DAPQVKSTPANIRYFELSNLDRNAEYQVKIAAMTVNGSGPFTEWN------RANTLENDLDETQV 907
                            ::|           :.:.|.|..|.|.:|      :......|:||...
  Fly   765 ----------------IAN-----------SLLLVTGLKPDTRYNLHFYNCKTRIFYGDIDEKTE 802

  Fly   908 PGKPIWISIHP--GANNIALHWGPPQHPEIKIRNYVLGWGRGIPDENTIELKETERYHILKNLES 970
            ...|..||...  ..|.:.|.|.||.:|..::.:|.:.|.........|..:.|:..:...|:..
  Fly   803 QDPPGTISNSKLIKQNGLKLMWEPPINPNGRVHHYDIRWSLDNVTHEAIVKECTKCSYKFPNVSE 867

  Fly   971 NMDYVVSLRARNVKGDGPPIYDNIKTRDEEPVDAPTPLEVPVGLRAITMSSSSIVVYWIDTMLNK 1035
            .....|::|.....|.|.|:|.:                                      |:|.
  Fly   868 TAKIHVAVRVMGDTGAGAPMYFD--------------------------------------MINN 894

  Fly  1036 N----QHVTDNRHYTVSYGIT-GSNRYRYHNTTDLNCMINDLRPNTQYEFAVKVVKGRRESSWSM 1095
            |    :..:::.|..|..||. ||       ...:.|:         :.|.:.::..:|  ::..
  Fly   895 NHTWLKEESESSHSEVYSGIAIGS-------LLSIACV---------FLFGLFIIFQQR--NFKA 941

  Fly  1096 SVLNSTYQNVPVTPPREVTVRLDEMNPPTVIVQWIPPKHTLGQITGYNIYYTTDTTKRDRDWSVE 1160
            .....|:...|      ..:....::..:.:     |..:.|.::|..:
  Fly   942 RAQGPTHLTTP------TDINFGNLSSASGM-----PGDSAGGLSGGTL---------------- 979

  Fly  1161 AFAGEETMLMLPNLKPYTTYYFKVQARTTKGANNAPFSALVSYTTSAAVTMQEPDTIAKGIDNEK 1225
                ::....:..|.|.:.|:.::          .|..:|...|::|||
  Fly   980 ----QQDCHEMQTLIPRSRYHIEL----------LPEHSLEYQTSTAAV---------------- 1014

  Fly  1226 LLYIIIAATAVVLLVVLLGVLLLCRRKPQSSPEHTKKSYQKNNVGVPKPPDLWIHHDQMELKNID 1290
                     |||.|....|.:.:.||..|...       .:.::|:
  Fly  1015 ---------AVVHLANGNGSVQVARRSDQDGA-------AQGDLGI------------------- 1044

  Fly  1291 KGLHTVT--PVCSDGASSSGALTL-------------------PRSV---------VHSEYEVET 1325
            .|:|.::  |:|..|.:|....|:                   |.:|         |.|..|:|.
  Fly  1045 AGVHNLSQLPLCGVGGTSPERKTVQDAMLQEAKAFYIPYRHTPPNAVALSSSKQCAVPSGSELEV 1109

  Fly  1326 PVPGHVTNSLDKRSYVPGY---------------------------MTTSMNGTMERPQYPRTQY 1363
            .||   .|||...:.:||.                           .::|.||:.:: |:.....
  Fly  1110 IVP---PNSLPLVTTMPGLGVVGGGGSGGGGVGGSSRRSGSLSSSSASSSSNGSSKK-QFHTNFV 1170

  Fly  1364 SHQNRS---HMTMEAGLSQQSLTQPQSNSMAQTPEHPY------------------GGYDANFCN 1407
            .|.|.:   ::..|         :..:.::..|.|..|                  ||...|..|
  Fly  1171 RHSNSNDGIYLLAE---------EEAAATLTPTSEREYAAVCLTNGFKLPADVAKSGGGTYNTTN 1226

  Fly  1408 AGNAAAGNGCVSTIESSKR----GHPLK-SFSVPGPPPTGGATPVTKHTPAVTIRPQNQSPYKKP 1467
            ..|::......|.....::    |:|:. |.:....|..|.|:....|:.||           |.
  Fly  1227 NNNSSTNTSQKSATAKERQPRGNGNPISFSHNACKVPANGPASVNVNHSSAV-----------KQ 1280

  Fly  1468 SFSAATPNRLQGGGSVVHSTDEI 1490
            |:.|||         |||...::
  Fly  1281 SWPAAT---------VVHRRAQV 1294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fra	NP_523716.2	Ig	36..140	CDD:299845	14/61 (23%)
		Ig	<180..222	CDD:299845	9/41 (22%)
		IG_like	257..340	CDD:214653	24/91 (26%)
		IGc2	264..327	CDD:197706	20/70 (29%)
		I-set	344..430	CDD:254352	22/85 (26%)
		Ig	363..428	CDD:299845	20/64 (31%)
		FN3	611..703	CDD:238020	18/102 (18%)
		FN3	711..799	CDD:238020	16/91 (18%)
		FN3	806..897	CDD:238020	10/96 (10%)
		FN3	908..989	CDD:238020	18/82 (22%)
		FN3	1011..1097	CDD:238020	12/90 (13%)
		FN3	1109..1205	CDD:238020	8/95 (8%)
		Neogenin_C	1273..1521	CDD:284094	53/301 (18%)
plum	NP_001163744.1	IG_like	170..241	CDD:214653	16/85 (19%)
		IGc2	175..235	CDD:197706	13/74 (18%)
		IG_like	284..356	CDD:214653	24/89 (27%)
		I-set	360..443	CDD:254352	21/83 (25%)
		IGc2	378..435	CDD:197706	17/57 (30%)
		FN3	804..886	CDD:238020	18/81 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4221
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810