DRSC/TRiP Functional Genomics Resources

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Protein Alignment fra and Cntn5

DIOPT Version :9

Sequence 1:NP_523716.2 Gene:fra / 36377 FlyBaseID:FBgn0011592 Length:1526 Species:Drosophila melanogaster
Sequence 2:XP_036010831.1 Gene:Cntn5 / 244682 MGIID:3042287 Length:1434 Species:Mus musculus


Alignment Length:1097 Identity:257/1097 - (23%)
Similarity:402/1097 - (36%) Gaps:260/1097 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 FTLEPQDAVVP---EGHSVLLQCAGTASIGRGGKSKSNLPSSVSIRWRGPDGQDLVIVGDTFRTQ 98
            |..||.|.:.|   :...|.|.|.     .||..|.       |.||. .:|.::.:..| :|..
Mouse   407 FVQEPDDVIFPTDSDEKKVALNCE-----VRGNPSP-------SYRWL-RNGTEIALESD-YRYS 457

  Fly    99 LKNGSLYISSVEENRGLTGAYQCLLTAEGVGSILSRPALVAIVRQPDLNQDFLETYLLPGQTAYF 163
            |.:|:..||:..|.|. :|.||||.| ...||||||.|.:                    |.||.
Mouse   458 LIDGTFIISNPSELRD-SGLYQCLAT-NSFGSILSREATL--------------------QFAYL 500

  Fly   164 RCMLGEANWQEGVK-------------HSVQ----WLKDDLP--LPLDKLRMVVLPNGALEIDEV 209
            ....|.......|:             ||.:    |:.::.|  :..|..|.:....|.|.|.:|
Mouse   501 GNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKV 565

  Fly   210 GPSDRGSYQCNVTSGSSSRLSSKTNLNIKKPSDP------GAENSVAPSFLVG-PSPKTVREGDT 267
            ..||.|||.|.|.       ::.||..:..|..|      |......|...|. |...|..:|.|
Mouse   566 QTSDVGSYICLVK-------NAVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTT 623

  Fly   268 VTLDCVANGVPKPQIKWLR-NGMDLDFNDLDSRFSIVGTGSLQISSAEDIDSGNYQCRASNTVDS 331
            |.::|.|.|.|.|.|.|:: ||.....:.|....:::...:||:.     |:|.|:|.|.|:...
Mouse   624 VKMECFALGNPVPTITWMKVNGYIPSKSRLRKSQAVLEIPNLQLD-----DAGIYECTAENSRGK 683

  Fly   332 LDAQATVQVQEPPKFIKAPKDTTAHEKDEPELKCDIWGKPKPVIRWLKNGDLITPNDYMQLVDGH 396
            ...:..:|:...|.:::...||........:.:|...|||:|..||||||..:.|...:..|:| 
Mouse   684 NSFRGQLQIFTYPHWVQKLNDTQLDSGSPLQWECKATGKPRPTYRWLKNGAPLLPQSRVDTVNG- 747

  Fly   397 NLKILGLLNSDAGMFQCVGTNAAGSVHAAARLRVV----------------------------PQ 433
            .|.|..:..|||||:||:..|..|:::|:|.|:::                            ||
Mouse   748 ILAIQSVNQSDAGMYQCLAENKYGAIYASAELKILASPPSFELNQVKKSIIVTKDRGVLIECEPQ 812

  Fly   434 G-----VKIKKRKSQGHSTKSLQTFDNLTKRRKPFNSGEQLRTKSGGSFPFPDEDDDLDDNDSGT 493
            |     :..:|......:.||:..|..:.:|.:                              ||
Mouse   813 GSPKPAISWRKGDKAVRANKSVSFFSTVVQRTR------------------------------GT 847

  Fly   494 TRLRIPSGKLPKFEQPLNDRRFNILNAGSALPLDNQSKSYEDDDDDY-----------------D 541
              ..:.:|..||    |..||..||..|| |.:.|.||:   |:..|                 .
Mouse   848 --CVVMNGWGPK----LARRRIAILPDGS-LRILNASKA---DEGKYICQGVNIFGSAEIIASLS 902

  Fly   542 EDDPAK-------------EALLEAYKQGEDAHKILDSWQQSKSKKSQQQKQ---------SPAS 584
            ..:|.:             |:::...|...||...:..:...|.:....:|:         ..:|
Mouse   903 VKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEKEGGHFENIRAQASS 967

  Fly   585 PDSPEQDPSVPHPG------GKPLDS-GLQARL-----PSQPRDLVAQIVKSRFVTLSWVEPLQN 637
            .|...::..:.|.|      ....|| ..:|.|     |..|..::.:.:.....||||.....|
Mouse   968 ADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGVVIVEEITESTATLSWSPATDN 1032

  Fly   638 AGDVVYYTVYYKMNNSEREQKMVTK----SHDDQQVNIQSLLPGRTYQFRVEANTNFGSGASSAP 698
            ...:..|.:..:...|...|.:.|.    :.|.:......|.|...|:|||.|....|:|..|.|
Mouse  1033 HSPISSYNLQARSPFSLGWQTVKTVPEVITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSIP 1097

  Fly   699 LEVSTQPEVNIAGP---PRNFEGYARSHKEIYVKWE--EPTVTNGEILKYRVYYSEN-------- 750
               |.....|.|.|   |.|..|.:....|:.:.||  .....|||...|.|.:..|        
Mouse  1098 ---SRMIRTNEAVPKTAPSNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEK 1159

  Fly   751 -----DSGADLYHDSTALEAVLTELRPHTDYVISVVPFNRNGMGDSSAEIRVKTFSSTPSEPPNN 810
                 ::...:|.|.:        :.|.|.:.:.|..:|..|.|..|..:.:.:....|:..|.:
Mouse  1160 MVTSSEASKFIYRDES--------VPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPTAAPTD 1216

  Fly   811 VTLEVTSSSSITVHWEPPAEEDRNGQITGYKIRYRKF---KDAPQVKSTPANIRYFELSNLDRNA 872
            ||....|.|.|.|.|:...|.  .|:..|::|.|.|.   :|:.:...|..|..:..|:.|:.|.
Mouse  1217 VTATSVSVSEIFVVWKHVKES--LGRPQGFEISYWKDTEPEDSVETVRTRGNESFVMLTGLEGNT 1279

  Fly   873 EYQVKIAAMTVNGSGPFTEWNRANTLENDLDETQVPGKPIWISIHPGANNIALHWGP--PQHPEI 935
            .|.:.:.|....|.||.:  ..|:|........:.||...|   ....:.::|.|.|  |...|.
Mouse  1280 LYHLTVRAYNGAGYGPPS--REASTTTKRHPPREPPGNLRW---EQQGSQVSLGWEPVRPLANES 1339

  Fly   936 KIRNYVL-----GWGRGIPDENTIELKETERYHILKNLESNMDYVVSLRARNVKGDG 987
            ::..|.:     |...|       ::.||::...:..|.....|::.:||.:..|||
Mouse  1340 EVMGYKVFYRQEGHSEG-------QVIETQKPQAVVPLPEAGVYIIEVRAYSEGGDG 1389

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fraNP_523716.2 Ig 36..140 CDD:299845 36/105 (34%)
Ig <180..222 CDD:299845 14/47 (30%)
IG_like 257..340 CDD:214653 23/83 (28%)
IGc2 264..327 CDD:197706 20/63 (32%)
I-set 344..430 CDD:254352 31/85 (36%)
Ig 363..428 CDD:299845 27/64 (42%)
FN3 611..703 CDD:238020 23/95 (24%)
FN3 711..799 CDD:238020 22/105 (21%)
FN3 806..897 CDD:238020 26/93 (28%)
FN3 908..989 CDD:238020 20/87 (23%)
FN3 1011..1097 CDD:238020
FN3 1109..1205 CDD:238020
Neogenin_C 1273..1521 CDD:284094
Cntn5XP_036010831.1 Ig strand D 741..745 CDD:409353 0/3 (0%)
Ig strand E 747..752 CDD:409353 2/5 (40%)
Ig strand F 761..768 CDD:409353 3/6 (50%)
Ig strand G 772..781 CDD:409353 3/8 (38%)
Ig 786..903 CDD:416386 26/156 (17%)
Ig strand A 786..791 CDD:409353 0/4 (0%)
Ig strand A' 794..799 CDD:409353 0/4 (0%)
Ig strand B 803..810 CDD:409353 0/6 (0%)
Ig strand C 818..822 CDD:409353 0/3 (0%)
Ig strand D 865..868 CDD:409353 2/2 (100%)
Ig strand E 869..874 CDD:409353 3/5 (60%)
Ig strand F 882..890 CDD:409353 1/7 (14%)
Ig strand G 896..903 CDD:409353 0/6 (0%)
Ig 905..1006 CDD:416386 15/100 (15%)
Ig strand A 905..911 CDD:409353 1/5 (20%)
Ig strand A' 914..919 CDD:409353 0/4 (0%)
Ig strand B 922..930 CDD:409353 1/7 (14%)
Ig strand C 939..943 CDD:409353 0/3 (0%)
Ig strand D 964..967 CDD:409353 0/2 (0%)
Ig strand E 968..972 CDD:409353 1/3 (33%)
Ig strand F 981..988 CDD:409353 1/6 (17%)
Ig strand G 995..999 CDD:409353 0/3 (0%)
FN3 1006..1103 CDD:238020 24/99 (24%)
FN3 1111..1203 CDD:238020 21/99 (21%)
FN3 1213..1304 CDD:238020 27/94 (29%)
FN3 1311..1397 CDD:238020 20/89 (22%)
Integrase_Zn 26..62 CDD:396557
rve 78..172 CDD:395538
IN_DBD_C 243..288 CDD:395437
Ig 404..499 CDD:416386 37/127 (29%)
Ig strand A 406..410 CDD:409353 1/2 (50%)
Ig strand A' 413..418 CDD:409353 1/4 (25%)
Ig strand B 424..432 CDD:409353 3/12 (25%)
Ig strand C 437..443 CDD:409353 3/13 (23%)
Ig strand C' 445..448 CDD:409353 1/2 (50%)
Ig strand D 455..459 CDD:409353 1/3 (33%)
Ig strand E 461..467 CDD:409353 2/5 (40%)
Ig strand F 474..483 CDD:409353 6/9 (67%)
Ig strand G 486..499 CDD:409353 8/32 (25%)
Ig 508..593 CDD:416386 21/91 (23%)
Ig strand A 509..514 CDD:409353 0/4 (0%)
Ig strand B 518..524 CDD:409353 0/5 (0%)
Ig strand C 532..538 CDD:409353 1/5 (20%)
Ig strand C' 543..545 CDD:409353 0/1 (0%)
Ig strand D 550..555 CDD:409353 1/4 (25%)
Ig strand E 558..562 CDD:409353 2/3 (67%)
Ig strand F 572..580 CDD:409353 4/14 (29%)
Ig strand G 582..593 CDD:409353 3/10 (30%)
Ig 606..693 CDD:416386 26/91 (29%)
Ig strand A 606..611 CDD:409353 1/4 (25%)
Ig strand A' 614..619 CDD:409353 1/4 (25%)
Ig strand B 622..631 CDD:409353 3/8 (38%)
Ig strand C 637..641 CDD:409353 1/3 (33%)
Ig strand C' 644..646 CDD:409353 1/1 (100%)
Ig strand D 654..657 CDD:409353 0/2 (0%)
Ig strand E 658..663 CDD:409353 0/4 (0%)
Ig strand F 671..679 CDD:409353 4/7 (57%)
Ig strand G 682..693 CDD:409353 1/10 (10%)
Ig 698..781 CDD:416386 30/83 (36%)
Ig strand A' 704..708 CDD:409353 2/3 (67%)
Ig strand B 712..720 CDD:409353 1/7 (14%)
Ig strand C 726..731 CDD:409353 2/4 (50%)
Ig strand C' 733..736 CDD:409353 1/2 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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