DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fra and zig-11

DIOPT Version :9

Sequence 1:	NP_523716.2	Gene:	fra / 36377	FlyBaseID:	FBgn0011592	Length:	1526	Species:	Drosophila melanogaster
Sequence 2:	NP_503523.2	Gene:	zig-11 / 189580	WormBaseID:	WBGene00021305	Length:	304	Species:	Caenorhabditis elegans

Alignment Length:	266	Identity:	59/266 - (22%)
Similarity:	94/266 - (35%)	Gaps:	70/266 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 RTQLKNGSLYISSVEENRGLTGAYQCLLTAEGVGSILSRPALVAIVRQPDLNQDFLETYLLPGQT 160
            :|.:...||:.:.::|||..||...|.:..   |:|..:|.....||..|..|
Worm    37 QTVIHGESLFSTDIDENRKTTGVLWCQVRE---GTIHYKPTWARFVRIRDQKQ------------ 86

  Fly   161 AYFRCMLGEANWQEGVKHSVQWLKDDLPLPLDKLRMVVLPNGALEIDEVGPSDRGSYQCNVTSGS 225
              ||..:|              |.||              ...|...:......|.|:|.:....
Worm    87 --FRADIG--------------LDDD--------------KAYLHFGQSKADASGKYRCEIKVPD 121

  Fly   226 SSRLSSKTNLNIKKPSDPGAENSVA---------PSFLVGPSPKTVREGDTVTLDCVANGVPKPQ 281
            :|.:..    |:...|.|..:|:..         |..:|||:.....: ....:.|...|.|:||
Worm   122 NSIIIG----NMFAYSHPVVKNNETWELKKSESEPFTVVGPAVYAPLD-SAARIQCPIVGYPEPQ 181

  Fly   282 IKWLRNGMDLDFNDLDSRFSIVGTGSLQISSAEDIDSGNYQCRASNTVDSLDAQATVQVQEPPKF 346
            |.|.::...|   :::.|.... .|.|.|..|::.|:|.|:|.|:|       |..||:..|.:.
Worm   182 IVWYKDKFPL---EIEGRVKFT-AGVLSIEGAQEEDAGVYRCEATN-------QFPVQIDGPEQH 235

  Fly   347 IKAPKD 352
            .....|
Worm   236 FAVKLD 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fra	NP_523716.2	Ig	36..140	CDD:299845	12/43 (28%)
		Ig	<180..222	CDD:299845	7/41 (17%)
		IG_like	257..340	CDD:214653	22/82 (27%)
		IGc2	264..327	CDD:197706	18/62 (29%)
		I-set	344..430	CDD:254352	1/9 (11%)
		Ig	363..428	CDD:299845
		FN3	611..703	CDD:238020
		FN3	711..799	CDD:238020
		FN3	806..897	CDD:238020
		FN3	908..989	CDD:238020
		FN3	1011..1097	CDD:238020
		FN3	1109..1205	CDD:238020
		Neogenin_C	1273..1521	CDD:284094
zig-11	NP_503523.2	IGc2	165..223	CDD:197706	18/62 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910