DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fra and AgaP_AGAP008734

DIOPT Version :9

Sequence 1:	NP_523716.2	Gene:	fra / 36377	FlyBaseID:	FBgn0011592	Length:	1526	Species:	Drosophila melanogaster
Sequence 2:	XP_314848.4	Gene:	AgaP_AGAP008734 / 1275587	VectorBaseID:	AGAP008734	Length:	292	Species:	Anopheles gambiae

Alignment Length:	388	Identity:	80/388 - (20%)
Similarity:	127/388 - (32%)	Gaps:	124/388 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 SSVEENRGLTGAYQCLLTAEGVGSILSRPALVAIVRQPDLNQDFLETYLLPGQTAYFRCMLGEAN 171
            :.|...||.|....|.:.::.       .|||:.:|:    |||  ..|..|...|   ...|..
Mosquito     9 TKVTAQRGGTALLPCTVISQS-------SALVSWIRR----QDF--QLLTVGLATY---SSDERF 57

  Fly   172 WQEGVKHSVQWLKDDLPLPLDKLRMVVLPNGALEIDEVGPSDRGSYQCNVTSGSSSRLSSKTNLN 236
            ..|.::|...|                    ||.|..|...|.|.|:|              .|:
Mosquito    58 LVEHLRHLGHW--------------------ALRIKSVRTEDEGLYEC--------------QLS 88

  Fly   237 IKKPSDPGAENSV--APSFLVGPSPKTVREGDTVTLDC-VANGVPKPQ-IKWLRNGMDLDFNDLD 297
            :........|..|  |.:.:||.....:.||.|:.|:| :.:....|. :.|......::|:.|:
Mosquito    89 VHPVQSVFVELKVVEAVAEIVGAPDLHIDEGSTLRLECKLQSATENPTFVFWYHEQNMVNFDQLN 153

  Fly   298 SRFSIVGTGSLQISSAEDIDSGNYQCRASNTVDSLDAQATVQVQEPPKFIKAPKDTTAHEKDEPE 362
            . ||:                         |.....|.|:......|.....|.:...||.  ||
Mosquito   154 G-FSV-------------------------TPFQPPATASHPSHLHPYLFPHPLEDDQHEL--PE 190

  Fly   363 LKCDIWG-----KPKPVIRWLKNGD-----LITPNDYMQLVDGHNLKILGLLN---SDAGMFQCV 414
            |..:..|     ..:.:.|.||.|.     .:||:....|:    |.:|.:..   ..||.:.|.
Mosquito   191 LSSEEQGYNLLDDDRLLQRSLKLGQDSAEPFLTPSSSSSLL----LAVLTIKEVHLRHAGNYTCA 251

  Fly   415 GTN---AAGSVHAAARLRVVPQGVKIKKRKSQGHSTKSLQTFDNLTKRRKPFNSGEQLRTKSG 474
            .:|   |:.:||       |.||   :|..:..|:.:|            ..:.|.:..::||
Mosquito   252 PSNARPASITVH-------VLQG---EKPAAMQHANRS------------QLDDGSKPSSRSG 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fra	NP_523716.2	Ig	36..140	CDD:299845	8/32 (25%)
		Ig	<180..222	CDD:299845	9/41 (22%)
		IG_like	257..340	CDD:214653	14/84 (17%)
		IGc2	264..327	CDD:197706	11/64 (17%)
		I-set	344..430	CDD:254352	24/101 (24%)
		Ig	363..428	CDD:299845	18/80 (23%)
		FN3	611..703	CDD:238020
		FN3	711..799	CDD:238020
		FN3	806..897	CDD:238020
		FN3	908..989	CDD:238020
		FN3	1011..1097	CDD:238020
		FN3	1109..1205	CDD:238020
		Neogenin_C	1273..1521	CDD:284094
AgaP_AGAP008734	XP_314848.4	V-set	6..102	CDD:284989	29/142 (20%)
		IG_like	11..101	CDD:214653	29/139 (21%)
		IG_like	<233..264	CDD:214653	8/37 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910