DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fra and AgaP_AGAP005069

DIOPT Version :9

Sequence 1:	NP_523716.2	Gene:	fra / 36377	FlyBaseID:	FBgn0011592	Length:	1526	Species:	Drosophila melanogaster
Sequence 2:	XP_313943.4	Gene:	AgaP_AGAP005069 / 1274751	VectorBaseID:	AGAP005069	Length:	354	Species:	Anopheles gambiae

Alignment Length:	231	Identity:	59/231 - (25%)
Similarity:	82/231 - (35%)	Gaps:	56/231 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   257 PSPKTVREGDTVTLDCVANGVPKPQIKWLRNGMDLDFNDL---------DSRFSIV-GTGS---- 307
            |...||..|.|..|.|....:....:.|:|.   .|.:.|         |.||.:: ..||
Mosquito    49 PRNITVTVGQTGFLHCRVERLGDKDVAWIRK---RDIHILTTGASTYTSDQRFQVLHPEGSVNWT 110

  Fly   308 LQISSAEDIDSGNYQCRASNTVDSLDAQATVQVQEPPKFIKAPKDTTAHEKDEPELKCDIWGKPK 372
            |||...:..|:|.|:|:. ||...:....|:.|.|....|..|.|.......|..:.|.|...|.
Mosquito   111 LQIKYPQVRDTGVYECQI-NTEPKMSLSYTLNVIELRARILGPTDIFVKSDSEITMTCVIQQGPH 174

  Fly   373 PV--IRWLKNGDLITP------------------NDYMQLVDGHNLKILGLLNSDAGMFQCVGTN 417
            .:  |.|.|...||.|                  .|:..::.. .|||..::.||.|.:.||.|.
Mosquito   175 ELGTIFWYKGSTLIEPLAQENELLPSEKRRIIVETDWTDVLTS-RLKIKRVVQSDTGNYTCVPTM 238

  Fly   418 AAGSVHAAARLRVVPQGVKIKKRKSQGHSTKSLQTF 453
            |..   |:....|:              |.|.:|||
Mosquito   239 AKS---ASVCAHVI--------------SGKFVQTF 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fra	NP_523716.2	Ig	36..140	CDD:299845
		Ig	<180..222	CDD:299845
		IG_like	257..340	CDD:214653	26/96 (27%)
		IGc2	264..327	CDD:197706	20/76 (26%)
		I-set	344..430	CDD:254352	25/105 (24%)
		Ig	363..428	CDD:299845	21/84 (25%)
		FN3	611..703	CDD:238020
		FN3	711..799	CDD:238020
		FN3	806..897	CDD:238020
		FN3	908..989	CDD:238020
		FN3	1011..1097	CDD:238020
		FN3	1109..1205	CDD:238020
		Neogenin_C	1273..1521	CDD:284094
AgaP_AGAP005069	XP_313943.4	Ig	48..142	CDD:299845	26/96 (27%)
		IG_like	49..142	CDD:214653	26/96 (27%)
		I-set	152..249	CDD:254352	24/100 (24%)
		Ig	163..235	CDD:143165	16/72 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910